IN2014DN06796A - - Google Patents

Download PDF

Info

Publication number
IN2014DN06796A
IN2014DN06796A IN6796DEN2014A IN2014DN06796A IN 2014DN06796 A IN2014DN06796 A IN 2014DN06796A IN 6796DEN2014 A IN6796DEN2014 A IN 6796DEN2014A IN 2014DN06796 A IN2014DN06796 A IN 2014DN06796A
Authority
IN
India
Prior art keywords
absence
determining
group
relates
analyte
Prior art date
Application number
Other languages
English (en)
Inventor
Daniel John Turner
Daniel George Fordham
Roger Charles Gill
Clive Gavin Brown
Stuart Reid
James Anthony Clarke
James White
Original Assignee
Oxford Nanopore Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Nanopore Tech Ltd filed Critical Oxford Nanopore Tech Ltd
Publication of IN2014DN06796A publication Critical patent/IN2014DN06796A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/36—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Actinomyces; from Streptomyces (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/49—Platelet-derived growth factor [PDGF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
IN6796DEN2014 2012-02-15 2013-02-14 IN2014DN06796A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261599240P 2012-02-15 2012-02-15
PCT/GB2013/050348 WO2013121201A1 (en) 2012-02-15 2013-02-14 Aptamer method

Publications (1)

Publication Number Publication Date
IN2014DN06796A true IN2014DN06796A (enExample) 2015-05-22

Family

ID=47749885

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6796DEN2014 IN2014DN06796A (enExample) 2012-02-15 2013-02-14

Country Status (8)

Country Link
US (3) US10739341B2 (enExample)
EP (1) EP2815235B1 (enExample)
JP (1) JP6275052B2 (enExample)
CN (1) CN104220874B (enExample)
AU (1) AU2013220156B2 (enExample)
CA (1) CA2864035C (enExample)
IN (1) IN2014DN06796A (enExample)
WO (1) WO2013121201A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
EP3190193A1 (en) 2010-07-14 2017-07-12 The Curators Of The University Of Missouri Nanopore-facilitated single molecule detection of nucleic acids
EP2815235B1 (en) 2012-02-15 2020-04-15 Oxford Nanopore Technologies Limited Aptamer method
JP6271505B2 (ja) 2012-04-10 2018-01-31 オックスフォード ナノポール テクノロジーズ リミテッド 変異体ライセニンポア
WO2014041337A1 (en) 2012-09-14 2014-03-20 Oxford Nanopore Technologies Limited Sample preparation method
WO2014072703A1 (en) 2012-11-06 2014-05-15 Oxford Nanopore Technologies Limited Quadruplex method
GB201318465D0 (en) * 2013-10-18 2013-12-04 Oxford Nanopore Tech Ltd Method
US9732379B2 (en) 2013-03-15 2017-08-15 The Curators Of The University Of Missouri Encoded nanopore sensor for multiplex nucleic acids detection
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201316849D0 (en) * 2013-09-23 2013-11-06 Isis Innovation Method
GB201406151D0 (en) * 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
EP3137627B1 (en) 2014-05-02 2025-07-30 Oxford Nanopore Technologies plc Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
KR20170042794A (ko) 2014-09-01 2017-04-19 브이아이비 브이지더블유 돌연변이체 csgg 포어
JP6485855B2 (ja) * 2014-10-03 2019-03-20 国立研究開発法人理化学研究所 アプタマーを用いた被検物の電気化学検出法
CN107109489B (zh) 2014-10-17 2021-11-30 牛津纳米孔技术公司 纳米孔rna表征方法
WO2016166232A1 (en) 2015-04-14 2016-10-20 Katholieke Universiteit Leuven Nanopores with internal protein adaptors
AU2016369071B2 (en) 2015-12-08 2022-05-19 Katholieke Universiteit Leuven Ku Leuven Research & Development Modified nanopores, compositions comprising the same, and uses thereof
AU2017225374B2 (en) 2016-03-02 2020-03-05 Oxford Nanopore Technologies Limited Mutant pore
EP4122949B1 (en) 2016-04-06 2024-06-05 Oxford Nanopore Technologies plc Mutant pore
CN105974125A (zh) * 2016-05-22 2016-09-28 杜护侠 一种心脑血管疾病特异性检测试剂盒
US10191040B2 (en) 2016-09-30 2019-01-29 Chin-Yih Hong Method of multiplex immunoassays utilizing differential affinity and methods for synthesizing aptamer-based reagents for multiplex immunoassays
GB201617886D0 (en) 2016-10-21 2016-12-07 Oxford Nanopore Technologies Limited Method
WO2018093976A1 (en) * 2016-11-16 2018-05-24 Nanopore Diagnostics, Llc Analysis of nucleic acids using probe with non-linear tag
GB201705764D0 (en) 2017-04-10 2017-05-24 Imp Innovations Ltd Analyte detection method
GB201707122D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Pore
CN117106037B (zh) 2017-06-30 2025-07-25 弗拉芒区生物技术研究所 新颖蛋白孔
GB201714478D0 (en) 2017-09-08 2017-10-25 Univ Bristol Sensor
US20200399693A1 (en) * 2018-02-12 2020-12-24 Oxford Nanopore Technologies, Ltd. Nanopore assemblies and uses thereof
CN111919118B (zh) * 2018-04-13 2025-09-05 豪夫迈·罗氏有限公司 用于检测和分析分析物的方法和组合物
US20200326325A1 (en) 2019-04-12 2020-10-15 Lisa Diamond Nanosensor chip with compound nanopores
GB202107192D0 (en) 2021-05-19 2021-06-30 Oxford Nanopore Tech Ltd Method

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198543A (en) 1989-03-24 1993-03-30 Consejo Superior Investigaciones Cientificas PHI29 DNA polymerase
CA2128891A1 (en) 1992-01-29 1993-08-05 Cylia Keller Polynucleotide immobilized support
US6031098A (en) * 1997-08-11 2000-02-29 California Institute Of Technology Detection and treatment of duplex polynucleotide damage
US6267872B1 (en) 1998-11-06 2001-07-31 The Regents Of The University Of California Miniature support for thin films containing single channels or nanopores and methods for using same
US6426231B1 (en) * 1998-11-18 2002-07-30 The Texas A&M University System Analyte sensing mediated by adapter/carrier molecules
US6246231B1 (en) * 1999-07-29 2001-06-12 Ascension Technology Corporation Magnetic field permeable barrier for magnetic position measurement system
CA2384100C (en) 1999-09-07 2011-03-29 The Regents Of The University Of California Methods of determining the presence of double stranded nucleic acids in a sample
EP1097993A3 (en) 1999-11-05 2004-01-07 National Institute of Advanced Industrial Science and Technology Functional ribozyme chimeric molecules capable of sliding
US20030008295A1 (en) * 2000-03-06 2003-01-09 Nassim Usman Nucleic acid sensor molecules
US20020197618A1 (en) 2001-01-20 2002-12-26 Sampson Jeffrey R. Synthesis and amplification of unstructured nucleic acids for rapid sequencing
US6706203B2 (en) * 2001-10-30 2004-03-16 Agilent Technologies, Inc. Adjustable nanopore, nanotome, and nanotweezer
WO2004041843A2 (en) 2002-05-17 2004-05-21 Board Of Regents, The University Of Texas System Hop - a novel cardiac-restricted transcriptional factor potentially useful for cardiac regeneration and specification
DE60324810D1 (de) 2002-09-20 2009-01-02 New England Biolabs Inc HELICASE-ABHuNGIGE AMPLIFIKATION VON NUKLEINSUREN
US20050250094A1 (en) * 2003-05-30 2005-11-10 Nanosphere, Inc. Method for detecting analytes based on evanescent illumination and scatter-based detection of nanoparticle probe complexes
US7347921B2 (en) 2003-07-17 2008-03-25 Agilent Technologies, Inc. Apparatus and method for threading a biopolymer through a nanopore
WO2005084412A2 (en) * 2004-03-05 2005-09-15 Archemix Corp. Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics
WO2006028508A2 (en) 2004-03-23 2006-03-16 President And Fellows Of Harvard College Methods and apparatus for characterizing polynucleotides
WO2005124888A1 (en) 2004-06-08 2005-12-29 President And Fellows Of Harvard College Suspended carbon nanotube field effect transistor
GB0505971D0 (en) 2005-03-23 2005-04-27 Isis Innovation Delivery of molecules to a lipid bilayer
US9233846B2 (en) * 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
US20070190543A1 (en) * 2005-11-14 2007-08-16 Applera Corporation Coded Molecules for Detecting Target Analytes
GB0523282D0 (en) 2005-11-15 2005-12-21 Isis Innovation Methods using pores
EP1994179A2 (en) * 2006-02-18 2008-11-26 Michael Strathmann Massively multiplexed sequencing
SG170028A1 (en) * 2006-02-24 2011-04-29 Callida Genomics Inc High throughput genome sequencing on dna arrays
WO2007117832A2 (en) * 2006-03-12 2007-10-18 Applera Corporation Methods of detecting target nucleic acids
WO2008066621A2 (en) * 2006-10-19 2008-06-05 Duke University Reversible platelet inhibition
US20100196203A1 (en) 2007-02-20 2010-08-05 Gurdial Singh Sanghera Formation of Lipid Bilayers
WO2008124107A1 (en) 2007-04-04 2008-10-16 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
US8698481B2 (en) 2007-09-12 2014-04-15 President And Fellows Of Harvard College High-resolution molecular sensor
WO2009046149A1 (en) 2007-10-01 2009-04-09 Applied Biosystems Inc. Chase ligation sequencing
ES2448426T3 (es) * 2007-10-12 2014-03-13 Pronota Nv Uso de aptámeros en proteómica
WO2009053691A1 (en) * 2007-10-22 2009-04-30 Pronota Nv Method of selecting aptamers
GB0724736D0 (en) * 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
US20110263459A1 (en) * 2008-03-12 2011-10-27 Borer Philip N Direct selection of structurally defined aptamers
US8628940B2 (en) 2008-09-24 2014-01-14 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
EP2307540B1 (en) 2008-07-07 2017-04-19 Oxford Nanopore Technologies Limited Enzyme-pore constructs
WO2010004273A1 (en) 2008-07-07 2010-01-14 Oxford Nanopore Technologies Limited Base-detecting pore
US20100092960A1 (en) 2008-07-25 2010-04-15 Pacific Biosciences Of California, Inc. Helicase-assisted sequencing with molecular beacons
US8642260B2 (en) * 2008-10-21 2014-02-04 The Research Foundation Of The City University Of New York Single quantum-dot based aptameric nanosensors
US20110008311A2 (en) 2008-11-03 2011-01-13 The Board Of Trustees Of The University Of Illinois Animal Model and Use of 17Beta-Hydroxysteroid Dehydrogenase Type 7 in the Diagnosis of Anencephaly
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
US20120100530A1 (en) 2009-01-30 2012-04-26 Oxford Nanopore Technologies Limited Enzyme mutant
WO2010086622A1 (en) 2009-01-30 2010-08-05 Oxford Nanopore Technologies Limited Adaptors for nucleic acid constructs in transmembrane sequencing
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US8986928B2 (en) 2009-04-10 2015-03-24 Pacific Biosciences Of California, Inc. Nanopore sequencing devices and methods
WO2010122293A1 (en) 2009-04-20 2010-10-28 Oxford Nanopore Technologies Limited Lipid bilayer sensor array
EP2507387B1 (en) 2009-12-01 2017-01-25 Oxford Nanopore Technologies Limited Biochemical analysis instrument and method
US9315857B2 (en) 2009-12-15 2016-04-19 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse label-tags
EP2537026B1 (en) 2010-02-19 2018-06-27 The Trustees Of The University Of Pennsylvania High-resolution analysis devices and related methods
US8557529B2 (en) * 2010-04-09 2013-10-15 International Business Machines Corporation Nanopore capture system
EP3190193A1 (en) 2010-07-14 2017-07-12 The Curators Of The University Of Missouri Nanopore-facilitated single molecule detection of nucleic acids
US20140051068A1 (en) 2010-09-07 2014-02-20 The Regents Of The University Of California Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme
WO2012088339A2 (en) 2010-12-22 2012-06-28 Genia Technologies, Inc. Nanopore-based single dna molecule characterization using speed bumps
EP2673638B1 (en) 2011-02-11 2019-10-30 Oxford Nanopore Technologies Limited Mutant pores
EP2689028B1 (en) 2011-03-23 2017-08-30 Pacific Biosciences Of California, Inc. Isolation of polymerase-nucleic acid complexes and loading onto substrates
EP3633370B1 (en) 2011-05-27 2024-05-01 Oxford Nanopore Technologies plc Method and apparatus for determining the presence, absence or characteristics of an analyte
IN2014DN00221A (enExample) 2011-07-25 2015-06-05 Oxford Nanopore Tech Ltd
CN104011866B (zh) 2011-07-27 2017-06-09 伊利诺伊大学评议会 用于生物分子表征的纳米孔传感器
SG10201510189WA (en) 2011-10-19 2016-01-28 Nugen Technologies Inc Compositions And Methods For Directional Nucleic Acid Amplification And Sequencing
EP2987870B1 (en) 2011-10-21 2020-02-19 Oxford Nanopore Technologies Limited Method of characterizing a target polynucleotide using a transmembrane pore and molecular motor
CN102430153A (zh) 2011-12-24 2012-05-02 中国人民解放军第三军医大学第二附属医院 一种基于交联技术的仿生骨界面、构建方法及其应用
WO2013098562A2 (en) 2011-12-29 2013-07-04 Oxford Nanopore Technologies Limited Enzyme method
WO2013098561A1 (en) 2011-12-29 2013-07-04 Oxford Nanopore Technologies Limited Method for characterising a polynucelotide by using a xpd helicase
EP2815235B1 (en) * 2012-02-15 2020-04-15 Oxford Nanopore Technologies Limited Aptamer method
BR102012007246A2 (pt) 2012-03-30 2016-02-10 Fundação Antonio Prudente métodos para prognóstico e classificação de resultados de um evento
JP6271505B2 (ja) 2012-04-10 2018-01-31 オックスフォード ナノポール テクノロジーズ リミテッド 変異体ライセニンポア
US10808231B2 (en) 2012-07-19 2020-10-20 Oxford Nanopore Technologies Limited Modified helicases
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
JP6429773B2 (ja) 2012-07-19 2018-11-28 オックスフォード ナノポール テクノロジーズ リミテッド 酵素構築物
WO2014041337A1 (en) 2012-09-14 2014-03-20 Oxford Nanopore Technologies Limited Sample preparation method
WO2014072703A1 (en) 2012-11-06 2014-05-15 Oxford Nanopore Technologies Limited Quadruplex method
GB201318465D0 (en) 2013-10-18 2013-12-04 Oxford Nanopore Tech Ltd Method
BR112015021788B1 (pt) 2013-03-08 2023-02-28 Oxford Nanopore Technologies Plc Métodos para mover uma ou mais helicases imobilizadas, para controlar o movimento de um polinucleotídeo alvo, para caracterizar um polinucleotídeo alvo e para controlar o carregamento de uma ou mais helicases em um polinucleotídeo alvo, uso de um poro de transmembrana e de um potencial aplicado e de um ou mais espaçadores, complexo, e, kit
GB201406151D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
CN117947149A (zh) 2013-10-18 2024-04-30 牛津纳米孔科技公开有限公司 经修饰的酶
EP3126515B1 (en) 2014-04-04 2018-08-29 Oxford Nanopore Technologies Limited Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid
CN107109489B (zh) 2014-10-17 2021-11-30 牛津纳米孔技术公司 纳米孔rna表征方法
JP6967006B2 (ja) * 2016-01-15 2021-11-17 クアンタポール， インコーポレイテッド 低減されたバックグラウンドの光学に基づくナノポア分析

Also Published As

Publication number Publication date
US20150177237A1 (en) 2015-06-25
EP2815235B1 (en) 2020-04-15
US11685922B2 (en) 2023-06-27
AU2013220156A1 (en) 2014-09-18
CA2864035C (en) 2021-05-18
CN104220874A (zh) 2014-12-17
US10739341B2 (en) 2020-08-11
EP2815235A1 (en) 2014-12-24
US20230392157A1 (en) 2023-12-07
CA2864035A1 (en) 2013-08-22
JP2015508893A (ja) 2015-03-23
AU2013220156B2 (en) 2018-08-09
WO2013121201A1 (en) 2013-08-22
CN104220874B (zh) 2017-05-24
US20210018500A1 (en) 2021-01-21
JP6275052B2 (ja) 2018-02-07

Similar Documents

Publication Publication Date Title
CA2864035C (en) A method for determining the presence of an analyte using an aptamer
EP2668501A2 (en) Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
IL257714B (en) Systems and methods for the analysis of multiple analytes
AU2017367238A8 (en) Methods and systems for characterizing analytes using nanopores
MX2013008538A (es) Amplificador compensado de fijacion de membrana para la secuenciacion de polinucleotido por nanoporo y otras aplicaciones.
BR112015001592A8 (pt) análise de imagem e medidas de amostras biológicas
MA40390A (fr) Procédés d'analyse impliquant des nanoparticules dissociables
BR112014018831A2 (pt) método para otimizar sensibilidade e/ou seletividade de um sensor para um ou mais analitos, método para formar um sensor para um ou mais analitos, kit para a detecção de um ou mais analitos, método de identificação de um aptâmero, composição de matéria e aptâmeros.
EP3311140B8 (en) Determining extracellular analyte concentration with nanoplasmonic sensors
PH12014501605A1 (en) Anti-lrp5 antibodies and methods of use
CR20140212A (es) Anticuerpos anti-htra1 y métodos de uso
EP2673631A1 (en) Methods and systems for determining the presence or amount of testosterone in a sample
WO2013166338A3 (en) Cell capture system and use thereof
MX2014014376A (es) Anticuerpos de anti-biotina y metodos de uso.
MX2014015088A (es) Anticuerpos anti-tofacitinib y usos de los mismos para monitorear farmacos.
EP4563709A3 (en) Methods and materials for assessing allelic imbalance
GB201011459D0 (en) Optical element, assembly and method for determining analyte concentration
WO2013181576A3 (en) Methods of evaluating and making biologics
HUP1200239A2 (en) Quantitative biomarkers of the erythrocyte membrane
EP2929068A4 (en) ELECTROCHEMICAL DISTRIBUTION SYSTEMS AND METHOD
MY165647A (en) Psa assay and reagent therefor
EP2809230A4 (en) SYSTEM FOR MEASURING BREATH ANALYTES
EP2856110A4 (en) DETERMINATION OF THE QUALITY OF SERUM SAMPLES
EP2821795A4 (en) sample preprocessing
MX353951B (es) Anticuerpos de anti-teofilina y metodos de uso.