JP5978291B2 - 一酸化炭素放出分子およびその使用 - Google Patents
一酸化炭素放出分子およびその使用 Download PDFInfo
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- JP5978291B2 JP5978291B2 JP2014506550A JP2014506550A JP5978291B2 JP 5978291 B2 JP5978291 B2 JP 5978291B2 JP 2014506550 A JP2014506550 A JP 2014506550A JP 2014506550 A JP2014506550 A JP 2014506550A JP 5978291 B2 JP5978291 B2 JP 5978291B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| US201161477036P | 2011-04-19 | 2011-04-19 | |
| US61/477,036 | 2011-04-19 | ||
| PCT/US2012/034264 WO2012145520A2 (en) | 2011-04-19 | 2012-04-19 | Carbon monoxide releasing molecules and uses thereof |
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| JP2014512389A JP2014512389A (ja) | 2014-05-22 |
| JP2014512389A5 JP2014512389A5 (enExample) | 2015-06-25 |
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| EP (1) | EP2699242B1 (enExample) |
| JP (1) | JP5978291B2 (enExample) |
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| PT (1) | PT2699242T (enExample) |
| WO (1) | WO2012145520A2 (enExample) |
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| CN103717224A (zh) * | 2011-06-07 | 2014-04-09 | 独立行政法人科学技术振兴机构 | 一氧化碳(co)对脂肪酸和胆固醇摄取的抑制 |
| ES2628634T3 (es) | 2011-07-21 | 2017-08-03 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas |
| EP3319613B1 (en) | 2015-07-07 | 2023-02-22 | The Research Foundation for The State University of New York | Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species |
| CN110914240B (zh) * | 2015-11-30 | 2024-02-20 | 奥塔哥创新有限公司 | 释放一氧化碳的降冰片烯酮化合物 |
| DE102017006393B4 (de) | 2017-07-06 | 2023-05-17 | Julius-Maximilians-Universität Würzburg | Verfahren zur oxidativen Freisetzung aus suspendierten CO-freisetzenden Molekülen (CORM) sowie Gasfreisetzungssystem und deren Verwendung |
| GB202004514D0 (en) | 2020-03-27 | 2020-05-13 | Inst De Medicina Molecular Joaeo Lobo Antunes | Treatment of Immunosuppressive Cancer |
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| US2870180A (en) | 1955-10-13 | 1959-01-20 | Ethyl Corp | Process for the preparation of hydrocarbon manganese carbonyl compounds |
| US3065250A (en) | 1960-05-13 | 1962-11-20 | Hercules Powder Co Ltd | Nitrile-metal carbonyl complexes |
| US3278570A (en) | 1961-04-11 | 1966-10-11 | Ethyl Corp | Molybdenum pentacarbonyl compounds and process for preparing same |
| US3452079A (en) | 1964-06-15 | 1969-06-24 | Merck & Co Inc | Acetic acid type compounds |
| CH536294A (de) | 1968-09-13 | 1973-04-30 | Schering Ag | Verfahren zur Herstellung von racemischen und optisch aktiven 4,6-Dichlor-4,6-östradienen |
| US3829504A (en) | 1970-06-04 | 1974-08-13 | Int Flavors & Fragrances Inc | Novel di-lower alkyl and lower alkylene acetals of 2-and 3-phenyl-pentenals |
| US3694232A (en) | 1970-06-04 | 1972-09-26 | Int Flavors & Fragrances Inc | Flavoring methods and compositions containing 3-phenyl pentenals |
| US3980583A (en) | 1974-02-19 | 1976-09-14 | Mobil Oil Corporation | Complexed metals bonded to inorganic oxides |
| NL7802482A (nl) | 1977-03-17 | 1978-09-19 | Klosa Josef | Preparaat voor de profylaxis en therapie van acne vulgaris en werkwijze voor de profylaxis en therapie van acne vulgaris met behulp van pyridinaldehyden. |
| US4312989A (en) | 1979-08-21 | 1982-01-26 | The United States Of America As Represented By The Secretary Of The Army | Pharmacologically active amine boranes |
| EP0034238B1 (en) | 1979-12-21 | 1985-04-17 | Duke University | Pharmacologically active amine-carboxyboranes |
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| US4613621A (en) | 1981-09-18 | 1986-09-23 | Hoerrmann Wilhelm | Fatty aldehydes and acids in the treatment of neurological and inflammatory diseases |
| DE3139358C2 (de) | 1981-10-02 | 1984-06-07 | Dragoco Gerberding & Co Gmbh, 3450 Holzminden | Verwendung von 1,1-Di(C↓1↓-C↓6↓-alkyl)-2-phenyl-ethan-Derivaten als Riechstoffe |
| US4535167A (en) | 1981-12-14 | 1985-08-13 | Merck & Co. Inc. | Chiral, N-protected, N-substituted α-amino acids |
| US4649151A (en) | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
| GB8407557D0 (en) | 1984-03-23 | 1984-05-02 | Hayward J A | Polymeric lipsomes |
| US4647555A (en) | 1984-10-25 | 1987-03-03 | The United States Of America As Represented By The Secretary Of The Army | Esters of boron analogues of amino acids |
| US4657902A (en) | 1985-03-25 | 1987-04-14 | The Rockefeller University | Therapeutic use of tin mesoporphyrin |
| US4709083A (en) | 1986-05-19 | 1987-11-24 | The United States Of America As Represented By The Secretary Of The Army | Method of making boron analogues |
| US4668670A (en) | 1986-06-20 | 1987-05-26 | The Rockefeller University | Tin diiododeuteroporphyrin and therapeutic use thereof |
| US4699903A (en) | 1986-06-20 | 1987-10-13 | The Rockefeller University | Therapeutic use of tin diiododeuteroporphyrin |
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| JPH0670025B2 (ja) | 1987-08-07 | 1994-09-07 | 鐘紡株式会社 | ベンゾチアゾ−ル誘導体および該化合物を有効成分とする抗リウマチ剤 |
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| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
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| HU211084B (en) | 1990-04-20 | 1995-10-30 | Brezo | Process for producing oral pharmaceutical composition of bone strengthening activity |
| DE4014762A1 (de) | 1990-05-05 | 1991-11-07 | Martin Prof Dr Wenzel | Verbindungen zur strahlentherapie oder diagnostik durch absorption von moessbauer-strahlung |
| WO1992003402A1 (fr) | 1990-08-24 | 1992-03-05 | Firmenich Sa | Compose cetonique polycyclique et son utilisation a titre d'ingredient parfumant |
| US5102670A (en) | 1990-09-14 | 1992-04-07 | Abraham Nader G | Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels |
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| IT1256450B (it) | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
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- 2012-04-19 US US14/112,786 patent/US9163044B2/en not_active Expired - Fee Related
- 2012-04-19 JP JP2014506550A patent/JP5978291B2/ja not_active Expired - Fee Related
- 2012-04-19 EP EP12774004.1A patent/EP2699242B1/en not_active Not-in-force
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| US20160137679A1 (en) | 2016-05-19 |
| ES2656237T3 (es) | 2018-02-26 |
| PT2699242T (pt) | 2018-01-22 |
| US20140142176A1 (en) | 2014-05-22 |
| EP2699242A4 (en) | 2015-03-11 |
| EP2699242A2 (en) | 2014-02-26 |
| WO2012145520A3 (en) | 2012-12-27 |
| JP2014512389A (ja) | 2014-05-22 |
| EP2699242B1 (en) | 2017-11-01 |
| US9163044B2 (en) | 2015-10-20 |
| WO2012145520A2 (en) | 2012-10-26 |
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