ITMI20020960A1 - Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumorale - Google Patents
Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumoraleInfo
- Publication number
- ITMI20020960A1 ITMI20020960A1 IT2002MI000960A ITMI20020960A ITMI20020960A1 IT MI20020960 A1 ITMI20020960 A1 IT MI20020960A1 IT 2002MI000960 A IT2002MI000960 A IT 2002MI000960A IT MI20020960 A ITMI20020960 A IT MI20020960A IT MI20020960 A1 ITMI20020960 A1 IT MI20020960A1
- Authority
- IT
- Italy
- Prior art keywords
- derivatives
- polyunsature
- radical
- linear aldehydes
- tumoral activities
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/21—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/24—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000960A ITMI20020960A1 (it) | 2002-05-07 | 2002-05-07 | Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumorale |
SI200331667T SI1501774T1 (sl) | 2002-05-07 | 2003-05-06 | Polinenasiäśeni ravnoveriĺ˝ni aldehidi in njihovi derivati s protiradikalno aktivnostjo |
PT03749867T PT1501774E (pt) | 2002-05-07 | 2003-05-06 | Aldeídos lineares polinsaturados e seus derivados com actividade anti-radicalar |
DK03749867T DK1501774T3 (da) | 2002-05-07 | 2003-05-06 | Flerumættede lineære aldehyder og deres derivater med anti-radikalvirkning |
AU2003232722A AU2003232722A1 (en) | 2002-05-07 | 2003-05-06 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity |
EP03749867A EP1501774B9 (en) | 2002-05-07 | 2003-05-06 | Polyunsaturated linear aldehydes and their derivatives with anti-radical activity |
PCT/EP2003/004720 WO2003095403A1 (en) | 2002-05-07 | 2003-05-06 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity |
AT03749867T ATE439338T1 (de) | 2002-05-07 | 2003-05-06 | Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkung |
ES03749867T ES2329890T3 (es) | 2002-05-07 | 2003-05-06 | Aldehidos poliinsaturados lineales y sus derivados con actividad antirradical. |
US10/513,450 US20050175555A1 (en) | 2002-05-07 | 2003-05-06 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity |
DE60328769T DE60328769D1 (de) | 2002-05-07 | 2003-05-06 | Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkung |
CY20091101096T CY1109512T1 (el) | 2002-05-07 | 2009-10-21 | Πολυακορεστες γραμμικες αλδευδες και τα παραγωγα τους με δραση εναντιον των ελευθερων ριζων |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000960A ITMI20020960A1 (it) | 2002-05-07 | 2002-05-07 | Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumorale |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20020960A0 ITMI20020960A0 (it) | 2002-05-07 |
ITMI20020960A1 true ITMI20020960A1 (it) | 2003-11-07 |
Family
ID=11449841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2002MI000960A ITMI20020960A1 (it) | 2002-05-07 | 2002-05-07 | Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumorale |
Country Status (12)
Country | Link |
---|---|
US (1) | US20050175555A1 (it) |
EP (1) | EP1501774B9 (it) |
AT (1) | ATE439338T1 (it) |
AU (1) | AU2003232722A1 (it) |
CY (1) | CY1109512T1 (it) |
DE (1) | DE60328769D1 (it) |
DK (1) | DK1501774T3 (it) |
ES (1) | ES2329890T3 (it) |
IT (1) | ITMI20020960A1 (it) |
PT (1) | PT1501774E (it) |
SI (1) | SI1501774T1 (it) |
WO (1) | WO2003095403A1 (it) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
US7968605B2 (en) * | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
EP2319518A1 (en) * | 2002-02-04 | 2011-05-11 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of CO-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
US20070207217A1 (en) * | 2003-02-03 | 2007-09-06 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Method for treating a mammal by administration of a compound having the ability to release CO |
GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
GB0605900D0 (en) * | 2006-03-23 | 2006-05-03 | Lipigen As | Modulators of nuclear receptors |
US9078852B2 (en) * | 2008-02-29 | 2015-07-14 | The Brigham And Women's Hospital, Inc. | Retinaldehyde in the treatment of obesity, diabetes and other conditions |
IT1391663B1 (it) * | 2008-11-10 | 2012-01-17 | Giuliani Spa | Uso di composti atti ad inibire l' attivita' dell'enzima 5alfa-reduttasi e composizioni farmaceutiche e cosmetiche che li contengono |
IT1394921B1 (it) * | 2008-11-10 | 2012-07-27 | Giuliani Spa | Uso di composti come principi attivi per migliorare l'azione di riparazione cellulare dell'epidermide umana, e composizioni farmaceutiche e cosmetiche che li contengono |
EP2241543A1 (en) * | 2009-04-17 | 2010-10-20 | Giuliani S.p.A. | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol |
IT1401289B1 (it) | 2010-04-22 | 2013-07-18 | Giuliani Spa | Composti dotati di attivita' antiossidante nei confronti dei radicali liberi, e composizioni farmaceutiche e cosmetiche che li contengono |
EP2407163A1 (en) * | 2010-07-16 | 2012-01-18 | Giuliani S.p.A. | Compounds with a skin pigmenting activity and pharmaceutical or cosmetic compositions containing them |
WO2012145520A2 (en) | 2011-04-19 | 2012-10-26 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
ES2628634T3 (es) | 2011-07-21 | 2017-08-03 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas |
CN117229132B (zh) * | 2023-11-10 | 2024-02-20 | 济南悟通生物科技有限公司 | 一种反式-2,4-壬二烯醛的合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3679792A (en) * | 1969-09-05 | 1972-07-25 | Wrigley W M Jun Co | Dialdehyde-containing anti-caries chewing gum compositions |
DE10200130A1 (de) * | 2002-01-04 | 2003-07-10 | Basf Ag | Verfahren zur Herstellung von Polyendialdehydmonoacetalen |
-
2002
- 2002-05-07 IT IT2002MI000960A patent/ITMI20020960A1/it unknown
-
2003
- 2003-05-06 DK DK03749867T patent/DK1501774T3/da active
- 2003-05-06 WO PCT/EP2003/004720 patent/WO2003095403A1/en not_active Application Discontinuation
- 2003-05-06 SI SI200331667T patent/SI1501774T1/sl unknown
- 2003-05-06 ES ES03749867T patent/ES2329890T3/es not_active Expired - Lifetime
- 2003-05-06 US US10/513,450 patent/US20050175555A1/en not_active Abandoned
- 2003-05-06 DE DE60328769T patent/DE60328769D1/de not_active Expired - Lifetime
- 2003-05-06 AT AT03749867T patent/ATE439338T1/de active
- 2003-05-06 AU AU2003232722A patent/AU2003232722A1/en not_active Abandoned
- 2003-05-06 PT PT03749867T patent/PT1501774E/pt unknown
- 2003-05-06 EP EP03749867A patent/EP1501774B9/en not_active Expired - Lifetime
-
2009
- 2009-10-21 CY CY20091101096T patent/CY1109512T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1501774A1 (en) | 2005-02-02 |
ATE439338T1 (de) | 2009-08-15 |
SI1501774T1 (sl) | 2009-12-31 |
EP1501774B1 (en) | 2009-08-12 |
WO2003095403A1 (en) | 2003-11-20 |
EP1501774B9 (en) | 2010-02-24 |
DK1501774T3 (da) | 2009-12-14 |
AU2003232722A1 (en) | 2003-11-11 |
ITMI20020960A0 (it) | 2002-05-07 |
US20050175555A1 (en) | 2005-08-11 |
CY1109512T1 (el) | 2014-08-13 |
ES2329890T3 (es) | 2009-12-02 |
DE60328769D1 (de) | 2009-09-24 |
PT1501774E (pt) | 2009-10-15 |
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