JP5889912B2 - アラニニルメイタンシノール抗体コンジュゲート - Google Patents

アラニニルメイタンシノール抗体コンジュゲート Download PDF

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JP5889912B2
JP5889912B2 JP2013539981A JP2013539981A JP5889912B2 JP 5889912 B2 JP5889912 B2 JP 5889912B2 JP 2013539981 A JP2013539981 A JP 2013539981A JP 2013539981 A JP2013539981 A JP 2013539981A JP 5889912 B2 JP5889912 B2 JP 5889912B2
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antibody
receptor
drug conjugate
drug
international publication
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JP2013544253A5 (enExample
JP2013544253A (ja
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ジョン フライゲア，
ジョン フライゲア，
ジャガス レディ ジャヌトゥラ，
ジャガス レディ ジャヌトゥラ，
トーマス ピロー，
トーマス ピロー，
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2013539981A 2010-11-17 2011-11-16 アラニニルメイタンシノール抗体コンジュゲート Active JP5889912B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41453510P 2010-11-17 2010-11-17
US61/414,535 2010-11-17
PCT/US2011/061031 WO2012074757A1 (en) 2010-11-17 2011-11-16 Alaninyl maytansinol antibody conjugates

Publications (3)

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JP2013544253A JP2013544253A (ja) 2013-12-12
JP2013544253A5 JP2013544253A5 (enExample) 2014-12-25
JP5889912B2 true JP5889912B2 (ja) 2016-03-22

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US (1) US20120121615A1 (enExample)
EP (1) EP2640727B1 (enExample)
JP (1) JP5889912B2 (enExample)
CN (1) CN103313990B (enExample)
CA (1) CA2816426A1 (enExample)
ES (1) ES2544608T3 (enExample)
WO (1) WO2012074757A1 (enExample)

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CN103313990A (zh) 2013-09-18
EP2640727A1 (en) 2013-09-25
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