JP5848748B2 - 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物 - Google Patents

感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物 Download PDF

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JP5848748B2
JP5848748B2 JP2013501437A JP2013501437A JP5848748B2 JP 5848748 B2 JP5848748 B2 JP 5848748B2 JP 2013501437 A JP2013501437 A JP 2013501437A JP 2013501437 A JP2013501437 A JP 2013501437A JP 5848748 B2 JP5848748 B2 JP 5848748B2
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alkyl
thia
formula
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トム・ヤオ−シアン・ウ
ゾウ・イーフェン
ティモシー・ゼット・ホフマン
パン・ジャンフェン
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IRM LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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JP2013501437A 2010-03-23 2011-03-23 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物 Expired - Fee Related JP5848748B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31655110P 2010-03-23 2010-03-23
US61/316,551 2010-03-23
PCT/US2011/029661 WO2011119759A1 (en) 2010-03-23 2011-03-23 Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.

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JP2013527142A JP2013527142A (ja) 2013-06-27
JP2013527142A5 JP2013527142A5 (https=) 2014-05-01
JP5848748B2 true JP5848748B2 (ja) 2016-01-27

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JP2013501437A Expired - Fee Related JP5848748B2 (ja) 2010-03-23 2011-03-23 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物

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US (2) US8808703B2 (https=)
EP (1) EP2549990A1 (https=)
JP (1) JP5848748B2 (https=)
KR (1) KR101853513B1 (https=)
CN (1) CN102905703B (https=)
AU (1) AU2011232421B2 (https=)
CA (1) CA2792938C (https=)
EA (2) EA023725B1 (https=)
MX (1) MX341395B (https=)
WO (1) WO2011119759A1 (https=)

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