JP5808764B2 - 放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム - Google Patents
放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム Download PDFInfo
- Publication number
- JP5808764B2 JP5808764B2 JP2013021428A JP2013021428A JP5808764B2 JP 5808764 B2 JP5808764 B2 JP 5808764B2 JP 2013021428 A JP2013021428 A JP 2013021428A JP 2013021428 A JP2013021428 A JP 2013021428A JP 5808764 B2 JP5808764 B2 JP 5808764B2
- Authority
- JP
- Japan
- Prior art keywords
- radioisotope
- pipe
- piping
- valve
- cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000746 purification Methods 0.000 claims description 98
- 238000003825 pressing Methods 0.000 claims description 85
- 239000000758 substrate Substances 0.000 claims description 65
- 238000000605 extraction Methods 0.000 claims description 28
- 210000000078 claw Anatomy 0.000 claims description 12
- 239000000243 solution Substances 0.000 description 131
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 60
- 238000000034 method Methods 0.000 description 50
- 239000007788 liquid Substances 0.000 description 49
- 239000002699 waste material Substances 0.000 description 27
- 238000007670 refining Methods 0.000 description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 24
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 22
- 230000015572 biosynthetic process Effects 0.000 description 22
- 239000007789 gas Substances 0.000 description 22
- 239000012217 radiopharmaceutical Substances 0.000 description 22
- 229940121896 radiopharmaceutical Drugs 0.000 description 22
- 230000002799 radiopharmaceutical effect Effects 0.000 description 22
- 238000003786 synthesis reaction Methods 0.000 description 22
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 21
- 238000010586 diagram Methods 0.000 description 19
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 18
- 101001128925 Zea mays 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic Proteins 0.000 description 17
- 239000003456 ion exchange resin Substances 0.000 description 17
- 229920003303 ion-exchange polymer Polymers 0.000 description 17
- -1 polypropylene Polymers 0.000 description 17
- 238000011084 recovery Methods 0.000 description 16
- 150000002500 ions Chemical class 0.000 description 15
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 13
- 101710158575 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase Proteins 0.000 description 12
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 12
- 229960001231 choline Drugs 0.000 description 12
- 239000003814 drug Substances 0.000 description 12
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 12
- 239000002504 physiological saline solution Substances 0.000 description 12
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 11
- 101150026858 VP30 gene Proteins 0.000 description 11
- 101150036892 VP40 gene Proteins 0.000 description 11
- 229940079593 drug Drugs 0.000 description 11
- 239000003444 phase transfer catalyst Substances 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- 108010068250 Herpes Simplex Virus Protein Vmw65 Proteins 0.000 description 10
- 101150077651 VP35 gene Proteins 0.000 description 10
- 230000002194 synthesizing effect Effects 0.000 description 10
- 101000933041 His1 virus (isolate Australia/Victoria) Major capsid protein Proteins 0.000 description 9
- 101710192266 Tegument protein VP22 Proteins 0.000 description 9
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 9
- 238000006243 chemical reaction Methods 0.000 description 9
- 101500019086 Ustilago maydis P6 virus KP6 killer toxin subunit alpha Proteins 0.000 description 8
- 238000004090 dissolution Methods 0.000 description 8
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 8
- 239000013077 target material Substances 0.000 description 8
- 101100023962 Zea mays VP15 gene Proteins 0.000 description 7
- 150000001875 compounds Chemical class 0.000 description 7
- 239000002245 particle Substances 0.000 description 7
- 239000002994 raw material Substances 0.000 description 7
- 239000011347 resin Substances 0.000 description 7
- 229920005989 resin Polymers 0.000 description 7
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
- 101800000316 Movement protein Proteins 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 101150010086 VP24 gene Proteins 0.000 description 6
- 238000004140 cleaning Methods 0.000 description 6
- 238000010790 dilution Methods 0.000 description 6
- 239000012895 dilution Substances 0.000 description 6
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 6
- 229940071870 hydroiodic acid Drugs 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 239000000741 silica gel Substances 0.000 description 6
- 229910002027 silica gel Inorganic materials 0.000 description 6
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 description 5
- 239000007864 aqueous solution Substances 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 239000000284 extract Substances 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 230000002093 peripheral effect Effects 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000003957 anion exchange resin Substances 0.000 description 4
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical class FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 235000006408 oxalic acid Nutrition 0.000 description 4
- 229910000027 potassium carbonate Inorganic materials 0.000 description 4
- 230000005855 radiation Effects 0.000 description 4
- JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 description 4
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 4
- 101001124039 Banna virus (strain Indonesia/JKT-6423/1980) Non-structural protein 4 Proteins 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- FFEARJCKVFRZRR-JJZBXVGDSA-N methionine c-11 Chemical compound [11CH3]SCC[C@H](N)C(O)=O FFEARJCKVFRZRR-JJZBXVGDSA-N 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- WAOQONBSWFLFPE-TXWZUYSVSA-N 3,5-dichloro-n-[[(2s)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide Chemical compound CCN1CCC[C@H]1CNC(=O)C1=C(O)C(Cl)=CC(Cl)=C1O[11CH3] WAOQONBSWFLFPE-TXWZUYSVSA-N 0.000 description 2
- 101000996791 Banna virus (strain Indonesia/JKT-6423/1980) Non-structural protein 2 Proteins 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 101001069760 Eumenes pomiformis Venom peptide 6 Proteins 0.000 description 2
- XPDWGBQVDMORPB-UHFFFAOYSA-N Fluoroform Chemical compound FC(F)F XPDWGBQVDMORPB-UHFFFAOYSA-N 0.000 description 2
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical group [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
- 230000004308 accommodation Effects 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- FJBFPHVGVWTDIP-UHFFFAOYSA-N dibromomethane Chemical compound BrCBr FJBFPHVGVWTDIP-UHFFFAOYSA-N 0.000 description 2
- 239000003792 electrolyte Substances 0.000 description 2
- 239000008151 electrolyte solution Substances 0.000 description 2
- OFBIFZUFASYYRE-JVVVGQRLSA-N ethyl 8-fluoro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate Chemical compound C1N([11CH3])C(=O)C2=CC(F)=CC=C2N2C=NC(C(=O)OCC)=C21 OFBIFZUFASYYRE-JVVVGQRLSA-N 0.000 description 2
- KIWQWJKWBHZMDT-UHFFFAOYSA-N homocysteine thiolactone Chemical compound NC1CCSC1=O KIWQWJKWBHZMDT-UHFFFAOYSA-N 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 239000012280 lithium aluminium hydride Substances 0.000 description 2
- NXPHGHWWQRMDIA-UHFFFAOYSA-M magnesium;carbanide;bromide Chemical compound [CH3-].[Mg+2].[Br-] NXPHGHWWQRMDIA-UHFFFAOYSA-M 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000007069 methylation reaction Methods 0.000 description 2
- 229910017604 nitric acid Inorganic materials 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- WAOQONBSWFLFPE-VIFPVBQESA-N 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide Chemical compound CCN1CCC[C@H]1CNC(=O)C1=C(O)C(Cl)=CC(Cl)=C1OC WAOQONBSWFLFPE-VIFPVBQESA-N 0.000 description 1
- 229910018509 Al—N Inorganic materials 0.000 description 1
- 229910021591 Copper(I) chloride Inorganic materials 0.000 description 1
- 101100034706 Dictyostelium discoideum rpl11 gene Proteins 0.000 description 1
- 240000001973 Ficus microcarpa Species 0.000 description 1
- 239000007818 Grignard reagent Substances 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 229920006355 Tefzel Polymers 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000000010 aprotic solvent Substances 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- CZKMPDNXOGQMFW-UHFFFAOYSA-N chloro(triethyl)germane Chemical compound CC[Ge](Cl)(CC)CC CZKMPDNXOGQMFW-UHFFFAOYSA-N 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- OXBLHERUFWYNTN-UHFFFAOYSA-M copper(I) chloride Chemical compound [Cu]Cl OXBLHERUFWYNTN-UHFFFAOYSA-M 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- QHSJIZLJUFMIFP-UHFFFAOYSA-N ethene;1,1,2,2-tetrafluoroethene Chemical compound C=C.FC(F)=C(F)F QHSJIZLJUFMIFP-UHFFFAOYSA-N 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000003682 fluorination reaction Methods 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 150000004795 grignard reagents Chemical group 0.000 description 1
- QOSATHPSBFQAML-UHFFFAOYSA-N hydrogen peroxide;hydrate Chemical compound O.OO QOSATHPSBFQAML-UHFFFAOYSA-N 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 229910001453 nickel ion Inorganic materials 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229950001518 raclopride Drugs 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- QRUBYZBWAOOHSV-UHFFFAOYSA-M silver trifluoromethanesulfonate Chemical compound [Ag+].[O-]S(=O)(=O)C(F)(F)F QRUBYZBWAOOHSV-UHFFFAOYSA-M 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/0005—Isotope delivery systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
- G01T1/161—Applications in the field of nuclear medicine, e.g. in vivo counting
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- High Energy & Nuclear Physics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nuclear Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013021428A JP5808764B2 (ja) | 2012-03-13 | 2013-02-06 | 放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム |
| KR20130026046A KR101487345B1 (ko) | 2012-03-13 | 2013-03-12 | 방사성동위원소 취급장치용 카세트, 방사성동위원소 취급장치, 및 방사성동위원소 취급시스템 |
| TW102106200A TWI520728B (zh) | 2012-03-13 | 2013-03-12 | Radioisotope operating system |
| CN201310079229.4A CN103301484B (zh) | 2012-03-13 | 2013-03-12 | 放射性同位素操作装置用盒、操作装置及操作系统 |
| US13/800,225 US20130266488A1 (en) | 2012-03-13 | 2013-03-13 | Cassette for radioactive isotope handling apparatus, radioactive isotope handling apparatus, and radioactive isotope handling system |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012056070 | 2012-03-13 | ||
| JP2012056070 | 2012-03-13 | ||
| JP2013021428A JP5808764B2 (ja) | 2012-03-13 | 2013-02-06 | 放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013215551A JP2013215551A (ja) | 2013-10-24 |
| JP2013215551A5 JP2013215551A5 (enExample) | 2015-06-25 |
| JP5808764B2 true JP5808764B2 (ja) | 2015-11-10 |
Family
ID=49127488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013021428A Active JP5808764B2 (ja) | 2012-03-13 | 2013-02-06 | 放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20130266488A1 (enExample) |
| JP (1) | JP5808764B2 (enExample) |
| KR (1) | KR101487345B1 (enExample) |
| CN (1) | CN103301484B (enExample) |
| TW (1) | TWI520728B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3035262B1 (fr) * | 2015-04-16 | 2020-02-07 | P M B | Dispositif de synthese d'un radio-traceur, installation comportant un tel dispositif et procede d'obtention d'un radio-traceur au moyen d'un tel dispositif |
| EP3878423B1 (en) * | 2017-03-24 | 2023-05-03 | Carefusion 303 Inc. | Waste container for automatic drug compounder |
| JP7178769B2 (ja) * | 2017-05-30 | 2022-11-28 | 住友重機械工業株式会社 | 放射性同位元素成分分離装置 |
| WO2020114353A1 (zh) * | 2018-12-03 | 2020-06-11 | 米度（南京）生物技术有限公司 | 用于放射性同位素操作系统的可更换模块以及放射性同位素操作系统 |
| CN111261309A (zh) * | 2018-12-03 | 2020-06-09 | 米度（南京）生物技术有限公司 | 放射性同位素操作系统及其废气处理装置 |
| CN113490514A (zh) * | 2018-12-03 | 2021-10-08 | 米度（南京）生物技术有限公司 | 用于放射性同位素操作系统的可更换模块以及放射性同位素操作系统 |
| CN111257921A (zh) * | 2018-12-03 | 2020-06-09 | 米度（南京）生物技术有限公司 | 放射性同位素操作系统及其可更换模块 |
| JP7460623B2 (ja) * | 2018-12-03 | 2024-04-02 | サーテックス メディカル インコーポレイテッド | 放射線塞栓術用マイクロスフェアを送達するための装置 |
| KR102186485B1 (ko) | 2020-04-16 | 2020-12-03 | 케이비엔지니어링(주) | 방사성 물질 저감 장치 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312592A (en) * | 1990-06-13 | 1994-05-17 | Scanditronix Ab | Disposable kit for preparation |
| WO1993011871A1 (en) * | 1991-12-10 | 1993-06-24 | Johansson Soeren | An apparatus for manufacturing of radioisotope labelled chemicals and pharmaceuticals |
| JP3008329B2 (ja) * | 1995-01-26 | 2000-02-14 | 信彦 中澤 | ラジオアイソトープ標識試薬調整用プレフィルドキット |
| EP1216715A1 (fr) * | 2000-12-22 | 2002-06-26 | Ion Beam Applications S.A. | Dispositif de synthèse de produits radiopharmaceutiques |
| CN1151163C (zh) * | 2001-07-26 | 2004-05-26 | 张锦明 | 一种制备2－18F－2脱氧－β－D－葡萄糖的设备及工艺 |
| JP4663995B2 (ja) * | 2004-02-20 | 2011-04-06 | 住友重機械工業株式会社 | 放射性薬剤合成投与装置 |
| US20050232861A1 (en) * | 2004-04-20 | 2005-10-20 | Buchanan Charles R | Microfluidic apparatus and method for synthesis of molecular imaging probes including FDG |
| US20060171852A1 (en) | 2005-02-02 | 2006-08-03 | Sandia National Laboratories | Microfluidics prototyping platform and components |
| US8518346B1 (en) * | 2005-02-02 | 2013-08-27 | Sandia Corporation | Multidimensional bioseparation with modular microfluidics |
| JP4361537B2 (ja) * | 2006-02-08 | 2009-11-11 | 住友重機械工業株式会社 | 放射性薬液合成装置のメンテナンス方法及び洗浄機能付放射性薬液合成装置 |
| JP4732187B2 (ja) * | 2006-02-27 | 2011-07-27 | 株式会社カネカ | 自動培養装置 |
| JP4926546B2 (ja) * | 2006-05-30 | 2012-05-09 | 住友重機械工業株式会社 | 放射性薬液合成装置の使用方法、及び放射性薬液合成装置 |
| KR101257764B1 (ko) * | 2011-04-15 | 2013-04-24 | 씨에스캠 주식회사 | 방사성의약품 제조장치 |
-
2013
- 2013-02-06 JP JP2013021428A patent/JP5808764B2/ja active Active
- 2013-03-12 TW TW102106200A patent/TWI520728B/zh active
- 2013-03-12 CN CN201310079229.4A patent/CN103301484B/zh active Active
- 2013-03-12 KR KR20130026046A patent/KR101487345B1/ko active Active
- 2013-03-13 US US13/800,225 patent/US20130266488A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013215551A (ja) | 2013-10-24 |
| CN103301484B (zh) | 2015-02-25 |
| CN103301484A (zh) | 2013-09-18 |
| KR20130105440A (ko) | 2013-09-25 |
| US20130266488A1 (en) | 2013-10-10 |
| TWI520728B (zh) | 2016-02-11 |
| TW201341342A (zh) | 2013-10-16 |
| KR101487345B1 (ko) | 2015-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5808764B2 (ja) | 放射性同位元素取り扱い装置用カセット、放射性同位元素取り扱い装置、及び放射性同位元素取り扱いシステム | |
| EP3068747B1 (en) | Dual run cassette for the synthesis of 18f-labelled compounds | |
| KR100835591B1 (ko) | 방사성 약액 합성장치의 사용방법, 및 방사성 약액합성장치 | |
| ES2598284T3 (es) | Método de purificación | |
| Keng et al. | Emerging technologies for decentralized production of PET tracers | |
| EP2761625A1 (en) | Cassette for radiopharmaceutical synthesis | |
| EP3218333B1 (en) | Fluoride trapping arrangement | |
| JP6664856B2 (ja) | 放射性医薬品を調製する複数の合成プロセスを連続して行う方法、この方法を行うためのデバイスおよびカセット | |
| US20130060017A1 (en) | Methods for synthesizing labeled compounds | |
| KR102155932B1 (ko) | Pet 추적자 정제 시스템 | |
| CN102391318A (zh) | 一种18f-fdg试剂盒及其在合成pet显像剂fdg中的应用 | |
| JP3993181B2 (ja) | 放射性標識化合物の製造装置および製造方法 | |
| Wang et al. | Automated synthesis of hypoxia imaging agent [18 F] FMISO based upon a modified Explora FDG 4 module | |
| JP4361537B2 (ja) | 放射性薬液合成装置のメンテナンス方法及び洗浄機能付放射性薬液合成装置 | |
| RU2843653C1 (ru) | Устройство для производства радиофармпрепаратов на основе фтора-18 | |
| JP2006056792A (ja) | 放射性標識薬自動合成装置 | |
| WO2023229997A1 (en) | Cgmp-compliant automated [18f]fspg production for clinical examination | |
| JP2005111301A (ja) | 反応物生成装置 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131203 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150508 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150515 |
|
| A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20150518 |
|
| A975 | Report on accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A971005 Effective date: 20150611 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150623 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150803 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20150908 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20150909 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5808764 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |