JP5797376B2 - 定量吸入器を用いたトレプロスチニル投与 - Google Patents

定量吸入器を用いたトレプロスチニル投与 Download PDF

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Publication number
JP5797376B2
JP5797376B2 JP2009511194A JP2009511194A JP5797376B2 JP 5797376 B2 JP5797376 B2 JP 5797376B2 JP 2009511194 A JP2009511194 A JP 2009511194A JP 2009511194 A JP2009511194 A JP 2009511194A JP 5797376 B2 JP5797376 B2 JP 5797376B2
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Prior art keywords
treprostinil
tre
inhalation
pulmonary
acceptable salt
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JP2009537246A5 (cg-RX-API-DMAC7.html
JP2009537246A (ja
Inventor
オルシェウスキー，ホルスト
ロシーニョ，ロバート
ルビン，ルイス，ジェイ．
シュメール，トーマス
シーガー，ワーナー
ステリット，カール
ヴォスウインケル，ロバート
Original Assignee
ユナイテッド セラピューティクス コーポレーション
ユナイテッド セラピューティクス コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009511194A 2006-05-15 2007-05-14 定量吸入器を用いたトレプロスチニル投与 Active JP5797376B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80001606P 2006-05-15 2006-05-15
US60/800,016 2006-05-15
PCT/US2007/068884 WO2007134292A2 (en) 2006-05-15 2007-05-14 Treprostinil administration using a metered dose inhaler

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2013185229A Division JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Division JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与

Publications (3)

Publication Number Publication Date
JP2009537246A JP2009537246A (ja) 2009-10-29
JP2009537246A5 JP2009537246A5 (cg-RX-API-DMAC7.html) 2010-06-17
JP5797376B2 true JP5797376B2 (ja) 2015-10-21

Family

ID=38544006

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2009511194A Active JP5797376B2 (ja) 2006-05-15 2007-05-14 定量吸入器を用いたトレプロスチニル投与
JP2013185229A Withdrawn JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Withdrawn JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与
JP2019038370A Pending JP2019112434A (ja) 2006-05-15 2019-03-04 定量吸入器を用いたトレプロスチニル投与

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013185229A Withdrawn JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Withdrawn JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与
JP2019038370A Pending JP2019112434A (ja) 2006-05-15 2019-03-04 定量吸入器を用いたトレプロスチニル投与

Country Status (8)

Country Link
US (10) US20080200449A1 (cg-RX-API-DMAC7.html)
EP (1) EP2026816B1 (cg-RX-API-DMAC7.html)
JP (4) JP5797376B2 (cg-RX-API-DMAC7.html)
KR (1) KR101390579B1 (cg-RX-API-DMAC7.html)
CN (1) CN101495122B (cg-RX-API-DMAC7.html)
CA (1) CA2654492C (cg-RX-API-DMAC7.html)
ES (1) ES2707548T3 (cg-RX-API-DMAC7.html)
WO (1) WO2007134292A2 (cg-RX-API-DMAC7.html)

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US20230062605A1 (en) 2023-03-02
US20120216801A1 (en) 2012-08-30
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