JP5715622B2 - 血小板レベルを増大させるためのペプチド療法 - Google Patents

血小板レベルを増大させるためのペプチド療法 Download PDF

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JP5715622B2
JP5715622B2 JP2012515626A JP2012515626A JP5715622B2 JP 5715622 B2 JP5715622 B2 JP 5715622B2 JP 2012515626 A JP2012515626 A JP 2012515626A JP 2012515626 A JP2012515626 A JP 2012515626A JP 5715622 B2 JP5715622 B2 JP 5715622B2
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thrombocytopenia
peptide
platelet
residue
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JP2012530130A (ja
JP2012530130A5 (enExample
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ミカル アブラハム,
ミカル アブラハム,
アムノン ペレド,
アムノン ペレド,
オルリー アイゼンバーグ,
オルリー アイゼンバーグ,
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バイオカイン セラピューティックス リミテッド
バイオカイン セラピューティックス リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/196Thrombopoietin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2012515626A 2009-06-14 2010-06-13 血小板レベルを増大させるためのペプチド療法 Active JP5715622B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18685709P 2009-06-14 2009-06-14
US61/186,857 2009-06-14
PCT/IL2010/000466 WO2010146578A2 (en) 2009-06-14 2010-06-13 Peptide therapy for increasing platelet levels

Publications (3)

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JP2012530130A JP2012530130A (ja) 2012-11-29
JP2012530130A5 JP2012530130A5 (enExample) 2013-08-01
JP5715622B2 true JP5715622B2 (ja) 2015-05-07

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JP2012515626A Active JP5715622B2 (ja) 2009-06-14 2010-06-13 血小板レベルを増大させるためのペプチド療法

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US (1) US9427456B2 (enExample)
EP (1) EP2442822B1 (enExample)
JP (1) JP5715622B2 (enExample)
KR (1) KR101719339B1 (enExample)
CN (1) CN102481332A (enExample)
BR (1) BRPI1009663A2 (enExample)
CA (1) CA2765345C (enExample)
ES (1) ES2462517T3 (enExample)
IL (1) IL216912A (enExample)
MX (1) MX2011013459A (enExample)
WO (1) WO2010146578A2 (enExample)

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US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
EP2426139B1 (en) 2002-08-27 2014-10-01 Biokine Therapeutics Ltd. CXCR4 antagonist and use thereof
CA2673719C (en) * 2006-12-21 2018-07-24 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery
BRPI1009663A2 (pt) 2009-06-14 2016-10-11 Biokine Therapeutics Ltd "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica"
EP2663320A1 (en) 2011-01-10 2013-11-20 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
JP2015154715A (ja) * 2012-05-22 2015-08-27 国立大学法人旭川医科大学 ヒト単核球由来の新規血管再生細胞群及びその分化誘導法
WO2014089478A1 (en) * 2012-12-07 2014-06-12 University Of Tennessee Research Foundation Methods of numerical analysis for platelet disorders and computer-readable media and systems for performing the same
CA3037762C (en) * 2014-05-15 2022-03-22 Enzychem Lifesciences Corporation Methods for treating leukopenia and thrombocytopenia
JP6547274B2 (ja) 2014-10-20 2019-07-24 株式会社デンソー 粒子状物質検出センサ
CN111375066B (zh) 2015-07-16 2023-04-25 百欧肯治疗有限公司 治疗癌症的组合物及方法
MX2018010125A (es) 2016-02-23 2019-03-28 Biolinerx Ltd Procedimientos de tratamiento de leucemia mieloide aguda.
CN113905754B (zh) * 2019-01-25 2025-03-11 詹森药业有限公司 减轻起疱剂和腐蚀性气体毒性作用的方法
CN115996741A (zh) * 2020-03-11 2023-04-21 百欧林纳克斯有限公司 用于治疗急性呼吸窘迫综合征及病毒感染的cxcr4抑制剂
CN116801896A (zh) 2020-12-30 2023-09-22 百欧林纳克斯有限公司 Bl-8040的组合物
WO2022144886A1 (en) 2020-12-30 2022-07-07 Biolinerx Ltd. Process for manufacturing peptide
CN118027155B (zh) * 2024-04-15 2024-07-16 中国人民解放军军事科学院军事医学研究院 一种tpor结合肽及其应用

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US20120094907A1 (en) 2012-04-19
CA2765345C (en) 2016-06-21
WO2010146578A3 (en) 2011-02-10
CN102481332A (zh) 2012-05-30
JP2012530130A (ja) 2012-11-29
EP2442822B1 (en) 2014-03-05
WO2010146578A2 (en) 2010-12-23
IL216912A (en) 2015-09-24
KR20120037463A (ko) 2012-04-19
EP2442822A2 (en) 2012-04-25
US9427456B2 (en) 2016-08-30
ES2462517T3 (es) 2014-05-23
KR101719339B1 (ko) 2017-03-23
IL216912A0 (en) 2012-02-29
MX2011013459A (es) 2012-05-08
BRPI1009663A2 (pt) 2016-10-11
CA2765345A1 (en) 2010-12-23
EP2442822A4 (en) 2013-01-23

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