JP5658274B2 - Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン - Google Patents

Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン Download PDF

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JP5658274B2
JP5658274B2 JP2012546092A JP2012546092A JP5658274B2 JP 5658274 B2 JP5658274 B2 JP 5658274B2 JP 2012546092 A JP2012546092 A JP 2012546092A JP 2012546092 A JP2012546092 A JP 2012546092A JP 5658274 B2 JP5658274 B2 JP 5658274B2
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pyrrolo
fluoro
pyridin
methyl
ylamino
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JP2013515729A (ja
JP2013515729A5 (enExample
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泰由 有川
泰由 有川
ジョーンズ、ベンジャミン
ラム、ベティー
ニエ、ジャ
スミス、クリストファー
昌志 高橋
昌志 高橋
ドン、キン
フェーフル、ヴィクトリア
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
  • Immunology (AREA)
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  • Neurology (AREA)
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  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
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  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
JP2012546092A 2009-12-23 2010-12-17 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン Active JP5658274B2 (ja)

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US28996909P 2009-12-23 2009-12-23
US61/289,969 2009-12-23
US38696410P 2010-09-27 2010-09-27
US61/386,964 2010-09-27
PCT/US2010/061146 WO2011079051A1 (en) 2009-12-23 2010-12-17 Fused heteroaromatic pyrrolidinones as syk inhibitors

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JP2014239677A Division JP5968983B2 (ja) 2009-12-23 2014-11-27 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン

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JP2013515729A JP2013515729A (ja) 2013-05-09
JP2013515729A5 JP2013515729A5 (enExample) 2014-02-06
JP5658274B2 true JP5658274B2 (ja) 2015-01-21

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JP2012546092A Active JP5658274B2 (ja) 2009-12-23 2010-12-17 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2014239677A Expired - Fee Related JP5968983B2 (ja) 2009-12-23 2014-11-27 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2016133849A Active JP6196710B2 (ja) 2009-12-23 2016-07-06 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2017158005A Pending JP2018009017A (ja) 2009-12-23 2017-08-18 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2018235779A Pending JP2019056000A (ja) 2009-12-23 2018-12-17 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2020107416A Pending JP2020164537A (ja) 2009-12-23 2020-06-23 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2022083170A Pending JP2022110135A (ja) 2009-12-23 2022-05-20 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン

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JP2018009017A (ja) * 2009-12-23 2018-01-18 武田薬品工業株式会社 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2019056000A (ja) * 2009-12-23 2019-04-11 武田薬品工業株式会社 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2020164537A (ja) * 2009-12-23 2020-10-08 武田薬品工業株式会社 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン
JP2022110135A (ja) * 2009-12-23 2022-07-28 武田薬品工業株式会社 Ｓｙｋ阻害剤としての縮合複素芳香族ピロリジノン

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