MA33909B1 - Pyrrolidinones accoles en tant d'inhibiteurs de syk - Google Patents

Pyrrolidinones accoles en tant d'inhibiteurs de syk

Info

Publication number
MA33909B1
MA33909B1 MA35044A MA35044A MA33909B1 MA 33909 B1 MA33909 B1 MA 33909B1 MA 35044 A MA35044 A MA 35044A MA 35044 A MA35044 A MA 35044A MA 33909 B1 MA33909 B1 MA 33909B1
Authority
MA
Morocco
Prior art keywords
pyrolidine
adherent
disorders
diseases
compounds
Prior art date
Application number
MA35044A
Other languages
Arabic (ar)
English (en)
Inventor
Yasuyoshi Arikawa
Benjamin Jones
Betty Lam
Zhe Nie
Christopher Smith
Masashi Takahashi
Qing Dong
Victoria Feher
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43618073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33909(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of MA33909B1 publication Critical patent/MA33909B1/fr

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Public Health (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Neurosurgery (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
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  • Ophthalmology & Optometry (AREA)
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Abstract

LA PRÉSENTE INVENTION CONCERNE DES COMPOSÉS DE FORMULE 1, ET DES SELS PHARMACEUTIQUEMENT ACCEPTABLES DE CEUX-CI, DANS LAQUELLE G, L1, L2, R1, R2, R3, ET R4 SONT TELS QUE DÉFINIS DANS LA DESCRIPTION. LA PRÉSENTE INVENTION CONCERNE ÉGALEMENT DES MATÉRIAUX ET DES PROCÉDÉS POUR LA PRÉPARATION DES COMPOSÉS DE FORMULE 1, DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, ET LEUR UTILISATION POUR LE TRAITEMENT DE TROUBLES, MALADIES, ET CONDITIONS IMPLIQUANT LE SYSTÈME IMMUNITAIRE ET L'INFLAMMATION, COMPRENANT LA POLYARTHRITE RHUMATOÏDE, LES MALIGNITÉS HÉMATOLOGIQUES, LES CANCERS ÉPITHÉLIAUX (OU CARCINOMES), ET D'AUTRES TROUBLES, MALADIES, ET CONDITIONS POUR LESQUELS L'INHIBITION DE SYK EST INDIQUÉE.
MA35044A 2009-12-23 2010-12-17 Pyrrolidinones accoles en tant d'inhibiteurs de syk MA33909B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28996909P 2009-12-23 2009-12-23
US38696410P 2010-09-27 2010-09-27
PCT/US2010/061146 WO2011079051A1 (fr) 2009-12-23 2010-12-17 Pyrrolidinones accolés en tant d'inhibiteurs de syk

Publications (1)

Publication Number Publication Date
MA33909B1 true MA33909B1 (fr) 2013-01-02

Family

ID=43618073

Family Applications (1)

Application Number Title Priority Date Filing Date
MA35044A MA33909B1 (fr) 2009-12-23 2010-12-17 Pyrrolidinones accoles en tant d'inhibiteurs de syk

Country Status (42)

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US (7) US9181255B2 (fr)
EP (4) EP3825316A1 (fr)
JP (7) JP5658274B2 (fr)
KR (1) KR101790255B1 (fr)
CN (1) CN102753548B (fr)
AR (1) AR081797A1 (fr)
AU (1) AU2010333804B2 (fr)
BR (1) BR112012015651B1 (fr)
CA (1) CA2786950C (fr)
CL (1) CL2012001745A1 (fr)
CO (1) CO6592058A2 (fr)
CR (1) CR20120392A (fr)
CY (1) CY1116736T1 (fr)
DK (1) DK2516434T3 (fr)
DO (1) DOP2012000180A (fr)
EA (1) EA021568B1 (fr)
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ES (1) ES2545616T3 (fr)
GE (1) GEP20156243B (fr)
HR (1) HRP20150878T1 (fr)
HU (1) HUE025177T2 (fr)
IL (1) IL220509A (fr)
JO (1) JO3108B1 (fr)
MA (1) MA33909B1 (fr)
ME (1) ME02186B (fr)
MX (1) MX2012007402A (fr)
MY (1) MY159257A (fr)
NZ (1) NZ601267A (fr)
PE (1) PE20130188A1 (fr)
PH (1) PH12012501311A1 (fr)
PL (1) PL2516434T3 (fr)
PT (1) PT2516434E (fr)
RS (1) RS54180B1 (fr)
SG (1) SG181857A1 (fr)
SI (1) SI2516434T1 (fr)
SM (1) SMT201500199B (fr)
TN (1) TN2012000316A1 (fr)
TW (1) TWI457339B (fr)
UA (1) UA107100C2 (fr)
UY (1) UY33151A (fr)
WO (1) WO2011079051A1 (fr)
ZA (1) ZA201205428B (fr)

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