DE602007001463D1 - Pyrimidin-, chinazolin-, pteridin- und triazinderivate - Google Patents
Pyrimidin-, chinazolin-, pteridin- und triazinderivateInfo
- Publication number
- DE602007001463D1 DE602007001463D1 DE602007001463T DE602007001463T DE602007001463D1 DE 602007001463 D1 DE602007001463 D1 DE 602007001463D1 DE 602007001463 T DE602007001463 T DE 602007001463T DE 602007001463 T DE602007001463 T DE 602007001463T DE 602007001463 D1 DE602007001463 D1 DE 602007001463D1
- Authority
- DE
- Germany
- Prior art keywords
- chinazolin
- pteridine
- pyrimidine
- triazine derivatives
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06111751 | 2006-03-27 | ||
PCT/EP2007/052571 WO2007110340A2 (en) | 2006-03-27 | 2007-03-19 | Pyrimidine, quinazoline, pteridine and triazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007001463D1 true DE602007001463D1 (de) | 2009-08-13 |
Family
ID=36997595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007001463T Active DE602007001463D1 (de) | 2006-03-27 | 2007-03-19 | Pyrimidin-, chinazolin-, pteridin- und triazinderivate |
Country Status (14)
Country | Link |
---|---|
US (1) | US7855194B2 (de) |
EP (1) | EP2001867B1 (de) |
JP (1) | JP2009531372A (de) |
KR (1) | KR101084484B1 (de) |
CN (1) | CN101405284A (de) |
AT (1) | ATE435223T1 (de) |
AU (1) | AU2007229555A1 (de) |
BR (1) | BRPI0710121A2 (de) |
CA (1) | CA2648025A1 (de) |
DE (1) | DE602007001463D1 (de) |
ES (1) | ES2326930T3 (de) |
IL (1) | IL194057A (de) |
MX (1) | MX2008012134A (de) |
WO (1) | WO2007110340A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2009009786A (es) * | 2007-03-14 | 2009-09-24 | Exelixis Inc | Inhibidores de la via de hedgehog. |
US8389533B2 (en) * | 2008-04-07 | 2013-03-05 | Amgen Inc. | Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors |
US8742110B2 (en) | 2010-08-18 | 2014-06-03 | Merck Sharp & Dohme Corp. | Spiroxazolidinone compounds |
WO2018183382A1 (en) | 2017-03-27 | 2018-10-04 | The Regents Of The University Of Colorado, A Body Corporate | Small molecule inhibitors of bacterial efflux pumps and methods of using same |
JOP20190284A1 (ar) * | 2017-06-14 | 2019-12-11 | Bayer Pharma AG | مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس |
RU2020124138A (ru) | 2017-12-22 | 2022-01-24 | Хиберселл, Инк. | Производные аминопиридина в качестве ингибиторов фосфатидилинозитолфосфаткиназы |
KR102328682B1 (ko) * | 2018-08-27 | 2021-11-18 | 주식회사 대웅제약 | 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물 |
TW202112767A (zh) | 2019-06-17 | 2021-04-01 | 美商佩特拉製藥公司 | 作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物 |
TW202208355A (zh) | 2020-05-04 | 2022-03-01 | 美商安進公司 | 作為骨髓細胞觸發受體2促效劑之雜環化合物及使用方法 |
CU20220065A7 (es) | 2020-05-04 | 2023-06-13 | Amgen Inc | Compuestos heterocíclicos como agonistas del receptor de activación expresado en las células mieloides 2 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2121031A1 (en) | 1971-04-29 | 1972-11-02 | Dr. Karl Thomae Gmbh, 7950 Biberach | Base-substd quinazolines - thrombocyte aggregation inhibitors |
US3931181A (en) * | 1973-07-27 | 1976-01-06 | Hoffmann-La Roche Inc. | 2,4-Diamino-5-benzylpyrimidines |
CH598231A5 (de) | 1973-07-27 | 1978-04-28 | Hoffmann La Roche | |
US3956495A (en) * | 1973-10-30 | 1976-05-11 | Eli Lilly And Company | 2,4-Diaminoquinazolines as antithrombotic agents |
EP0009465A1 (de) * | 1978-09-20 | 1980-04-02 | Ciba-Geigy Ag | N-(1-(4-Amino-2-chinazolinyl)-3- oder -4-piperidyl-lactame, Verfahren zu ihrer Herstellung, sowie pharmazeutische Präparate enthaltend diese Verbindungen |
US4309541A (en) * | 1978-09-20 | 1982-01-05 | Ciba-Geigy Corporation | Piperidinyl-lactams |
FR2514765A1 (fr) * | 1981-10-21 | 1983-04-22 | Sanofi Sa | Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central |
KR100190299B1 (ko) | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
FR2669923B1 (fr) | 1990-11-29 | 1993-01-29 | Rhone Poulenc Chimie | Procede de preparation de composes aromatiques alkoxyles. |
TW504510B (en) * | 1996-05-10 | 2002-10-01 | Janssen Pharmaceutica Nv | 2,4-diaminopyrimidine derivatives |
EP0921116B1 (de) | 1997-12-04 | 2003-06-18 | F. Hoffmann-La Roche Ag | N-(4-carbamimido-phenyl)-glycinamidderivate |
TR200101744T2 (tr) | 1998-12-14 | 2001-12-21 | F. Hoffmann-La Roche Ag | Fenilglisin türevleri. |
WO2001032633A1 (de) | 1999-11-04 | 2001-05-10 | Basilea Pharmaceutica Ag | Substituierte 5-benzyl-2,4-diaminopyrimidine |
FR2802206B1 (fr) * | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
FR2807038B1 (fr) | 2000-04-03 | 2002-08-16 | Sanofi Synthelabo | Nouveaux derives d'indolin-2-one, leur preparation et les compositions pharmaceutiques les contenant |
JP4033676B2 (ja) | 2000-04-27 | 2008-01-16 | バジリア ファルマスーチカ アーゲー | 抗菌剤としてのクロメニルメチルピリミジンジアミン類 |
US6548694B2 (en) | 2000-05-23 | 2003-04-15 | Hoffman-La Roche Inc. | N-(4-carbamimidoyl-phenyl)-glycine derivatives |
DE10228132A1 (de) | 2002-06-24 | 2004-01-22 | Arzneimittelwerk Dresden Gmbh | Amide cyclischer Aminosäuren als PDE 4 Inhibitoren |
WO2004052862A1 (ja) * | 2002-12-10 | 2004-06-24 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびその医薬用途 |
AU2005232745A1 (en) | 2004-04-13 | 2005-10-27 | Astellas Pharma Inc. | Polycyclic pyrimidines as potassium ion channel modulators |
-
2007
- 2007-03-15 US US11/724,688 patent/US7855194B2/en not_active Expired - Fee Related
- 2007-03-19 CN CNA2007800103078A patent/CN101405284A/zh active Pending
- 2007-03-19 MX MX2008012134A patent/MX2008012134A/es active IP Right Grant
- 2007-03-19 AU AU2007229555A patent/AU2007229555A1/en not_active Abandoned
- 2007-03-19 CA CA002648025A patent/CA2648025A1/en not_active Abandoned
- 2007-03-19 AT AT07727049T patent/ATE435223T1/de active
- 2007-03-19 WO PCT/EP2007/052571 patent/WO2007110340A2/en active Application Filing
- 2007-03-19 DE DE602007001463T patent/DE602007001463D1/de active Active
- 2007-03-19 BR BRPI0710121-0A patent/BRPI0710121A2/pt not_active IP Right Cessation
- 2007-03-19 ES ES07727049T patent/ES2326930T3/es active Active
- 2007-03-19 KR KR1020087026236A patent/KR101084484B1/ko not_active IP Right Cessation
- 2007-03-19 EP EP07727049A patent/EP2001867B1/de not_active Not-in-force
- 2007-03-19 JP JP2009502017A patent/JP2009531372A/ja not_active Ceased
-
2008
- 2008-09-11 IL IL194057A patent/IL194057A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BRPI0710121A2 (pt) | 2012-07-17 |
IL194057A0 (en) | 2009-08-03 |
CA2648025A1 (en) | 2007-10-04 |
WO2007110340A2 (en) | 2007-10-04 |
CN101405284A (zh) | 2009-04-08 |
KR101084484B1 (ko) | 2011-11-21 |
EP2001867B1 (de) | 2009-07-01 |
ATE435223T1 (de) | 2009-07-15 |
ES2326930T3 (es) | 2009-10-21 |
US20070225271A1 (en) | 2007-09-27 |
WO2007110340A3 (en) | 2007-11-15 |
KR20080104074A (ko) | 2008-11-28 |
IL194057A (en) | 2012-07-31 |
EP2001867A2 (de) | 2008-12-17 |
AU2007229555A1 (en) | 2007-10-04 |
US7855194B2 (en) | 2010-12-21 |
MX2008012134A (es) | 2008-10-03 |
JP2009531372A (ja) | 2009-09-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |