JP5607025B2 - 化合物、組成物およびそれらを作製する方法 - Google Patents

化合物、組成物およびそれらを作製する方法 Download PDF

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Publication number
JP5607025B2
JP5607025B2 JP2011505265A JP2011505265A JP5607025B2 JP 5607025 B2 JP5607025 B2 JP 5607025B2 JP 2011505265 A JP2011505265 A JP 2011505265A JP 2011505265 A JP2011505265 A JP 2011505265A JP 5607025 B2 JP5607025 B2 JP 5607025B2
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compound
pp2a
compounds
activity
formula
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JP2011505265A
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Japanese (ja)
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JP2011518196A (ja
JP2011518196A5 (enExample
Inventor
マイケル ボロンコフ，
スコット バファイ，
マックスウェル ストック，
ジェフリー ビー． ストック，
チュー リー，
ソン−ユブ リー，
ハオミン グー，
ゴーパル サーンガダラン，
Original Assignee
シグナム バイオサイエンシーズ， インコーポレイテッド
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Publication of JP2011518196A5 publication Critical patent/JP2011518196A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2011505265A 2008-04-21 2009-04-21 化合物、組成物およびそれらを作製する方法 Expired - Fee Related JP5607025B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12494908P 2008-04-21 2008-04-21
US61/124,949 2008-04-21
US12520508P 2008-04-23 2008-04-23
US61/125,205 2008-04-23
US12790008P 2008-05-16 2008-05-16
US61/127,900 2008-05-16
PCT/US2009/041321 WO2009132051A1 (en) 2008-04-21 2009-04-21 Compounds, compositions and methods for making the same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2012082834A Division JP2012126753A (ja) 2008-04-21 2012-03-30 化合物、組成物およびそれらを作製する方法
JP2014161026A Division JP2014208706A (ja) 2008-04-21 2014-08-07 化合物、組成物およびそれらを作製する方法

Publications (3)

Publication Number Publication Date
JP2011518196A JP2011518196A (ja) 2011-06-23
JP2011518196A5 JP2011518196A5 (enExample) 2013-05-16
JP5607025B2 true JP5607025B2 (ja) 2014-10-15

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Family Applications (5)

Application Number Title Priority Date Filing Date
JP2011505265A Expired - Fee Related JP5607025B2 (ja) 2008-04-21 2009-04-21 化合物、組成物およびそれらを作製する方法
JP2012082834A Withdrawn JP2012126753A (ja) 2008-04-21 2012-03-30 化合物、組成物およびそれらを作製する方法
JP2014161026A Pending JP2014208706A (ja) 2008-04-21 2014-08-07 化合物、組成物およびそれらを作製する方法
JP2016086766A Expired - Fee Related JP6383377B2 (ja) 2008-04-21 2016-04-25 化合物、組成物およびそれらを作製する方法
JP2016086767A Pending JP2016135809A (ja) 2008-04-21 2016-04-25 化合物、組成物およびそれらを作製する方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2012082834A Withdrawn JP2012126753A (ja) 2008-04-21 2012-03-30 化合物、組成物およびそれらを作製する方法
JP2014161026A Pending JP2014208706A (ja) 2008-04-21 2014-08-07 化合物、組成物およびそれらを作製する方法
JP2016086766A Expired - Fee Related JP6383377B2 (ja) 2008-04-21 2016-04-25 化合物、組成物およびそれらを作製する方法
JP2016086767A Pending JP2016135809A (ja) 2008-04-21 2016-04-25 化合物、組成物およびそれらを作製する方法

Country Status (7)

Country Link
US (2) US9486441B2 (enExample)
EP (1) EP2282735B1 (enExample)
JP (5) JP5607025B2 (enExample)
CN (1) CN102014897B (enExample)
AU (3) AU2009239430B2 (enExample)
CA (1) CA2758424C (enExample)
WO (1) WO2009132051A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014208706A (ja) * 2008-04-21 2014-11-06 シグナム バイオサイエンシーズ， インコーポレイテッド 化合物、組成物およびそれらを作製する方法

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US20090175973A1 (en) * 2007-09-05 2009-07-09 Nina Vikhrieva Coffee cherry compositions and methods for their use in the treatment of diabetes and diabetes related disorders
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US9073851B2 (en) 2011-10-28 2015-07-07 Board Of Regents, The University Of Texas System Compositions and methods for treating cancer
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