JP5393654B2 - 改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤/調節剤のn−オキシド誘導体及び/又はジ−n−オキシド誘導体 - Google Patents

改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤/調節剤のn−オキシド誘導体及び/又はジ−n−オキシド誘導体 Download PDF

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JP5393654B2
JP5393654B2 JP2010502976A JP2010502976A JP5393654B2 JP 5393654 B2 JP5393654 B2 JP 5393654B2 JP 2010502976 A JP2010502976 A JP 2010502976A JP 2010502976 A JP2010502976 A JP 2010502976A JP 5393654 B2 JP5393654 B2 JP 5393654B2
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ヴィクストレム、ホーカン、ヴィ.
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イヴァックス インテルナツィオナール ゲゼルシャフト ミット ベシュレンクテル ハフツンク
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    • C07ORGANIC CHEMISTRY
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    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94Oxygen atom, e.g. piperidine N-oxide
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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JP2010502976A 2007-04-12 2008-04-11 改善された心血管副作用プロフィールを呈する、ドーパミン受容体安定剤/調節剤のn−オキシド誘導体及び/又はジ−n−オキシド誘導体 Expired - Fee Related JP5393654B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0700893 2007-04-12
SE0700893-1 2007-04-12
PCT/SE2008/050414 WO2008127188A1 (en) 2007-04-12 2008-04-11 N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles

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JP2010523651A JP2010523651A (ja) 2010-07-15
JP2010523651A5 JP2010523651A5 (https=) 2011-05-26
JP5393654B2 true JP5393654B2 (ja) 2014-01-22

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US (1) US9139525B2 (https=)
EP (1) EP2146961B1 (https=)
JP (1) JP5393654B2 (https=)
CN (1) CN101711236B (https=)
AU (1) AU2008239841B2 (https=)
BR (1) BRPI0810161A2 (https=)
CA (1) CA2683719C (https=)
CY (1) CY1115337T1 (https=)
DK (1) DK2146961T3 (https=)
ES (1) ES2458592T3 (https=)
HR (1) HRP20140380T1 (https=)
IL (1) IL201401A (https=)
MX (1) MX2009011020A (https=)
NZ (1) NZ580856A (https=)
PL (1) PL2146961T3 (https=)
PT (1) PT2146961E (https=)
RU (1) RU2470013C2 (https=)
SI (1) SI2146961T1 (https=)
WO (1) WO2008127188A1 (https=)

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US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
CA3050700C (en) 2017-01-20 2023-10-03 Prilenia Neurotherapeutics Ltd. Use of pridopidine for the treatment of fragile x syndrome
SI4154882T1 (sl) 2017-08-14 2026-01-30 Prilenia Neurotherapeutics Ltd. Zdravljenje amiotrofične lateralne skleroze s pridopidinom
CA3073568A1 (en) 2017-08-30 2019-03-07 Prilenia Neurotherapeutics Ltd. High concentration dosage forms of pridopidine
JP2020533296A (ja) 2017-09-08 2020-11-19 プリレニア ニューロセラピューティクス リミテッド 薬物誘発性ジスキネジアを治療するためのプリドピジン
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
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CN116472043A (zh) * 2020-10-20 2023-07-21 普瑞尼亚神经治疗有限公司 普利多匹定和类似物用于治疗焦虑和抑郁的用途

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TWI579272B (zh) * 2011-12-08 2017-04-21 梯瓦製藥國際有限責任公司 普多比啶(pridopidine)之氫溴酸鹽
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CA2683719C (en) 2015-07-14
EP2146961B1 (en) 2014-01-29
CN101711236A (zh) 2010-05-19
ES2458592T3 (es) 2014-05-06
HRP20140380T1 (hr) 2014-08-15
AU2008239841B2 (en) 2013-07-18
CA2683719A1 (en) 2008-10-23
CY1115337T1 (el) 2017-01-04
SI2146961T1 (sl) 2014-08-29
CN101711236B (zh) 2012-10-31
DK2146961T3 (da) 2014-04-28
EP2146961A1 (en) 2010-01-27
EP2146961A4 (en) 2011-08-03
IL201401A0 (en) 2010-05-31
PL2146961T3 (pl) 2014-09-30
PT2146961E (pt) 2014-04-30
IL201401A (en) 2015-10-29
RU2470013C2 (ru) 2012-12-20
JP2010523651A (ja) 2010-07-15
NZ580856A (en) 2011-11-25
WO2008127188A1 (en) 2008-10-23
US20100105736A1 (en) 2010-04-29
AU2008239841A1 (en) 2008-10-23
BRPI0810161A2 (pt) 2014-12-30
RU2009141300A (ru) 2011-05-20
MX2009011020A (es) 2009-10-30
US9139525B2 (en) 2015-09-22

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