|
US3342824A
(en)
*
|
1964-12-07 |
1967-09-19 |
Lilly Co Eli |
Normorphines
|
|
GB1123768A
(en)
*
|
1966-07-29 |
1968-08-14 |
Smith Kline French Lab |
New thebaine and oripavine derivatives and processes for preparing the same
|
|
US3466277A
(en)
*
|
1966-12-13 |
1969-09-09 |
Boehringer Sohn Ingelheim |
N-allylic cyclohexyl lower alkyl normorphines
|
|
US3905981A
(en)
*
|
1973-10-12 |
1975-09-16 |
Research Corp |
N-dealkylation of tertiary amines
|
|
NO802139L
(no)
*
|
1979-08-09 |
1981-02-10 |
Mallinckrodt Inc |
Utgangsforbindelser for fremstilling av morfinderivater, samt fremgangsmaate til fremstilling av utgangsforbindelsene
|
|
US4613668A
(en)
*
|
1983-12-22 |
1986-09-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl
|
|
US4722928A
(en)
*
|
1985-12-02 |
1988-02-02 |
E. I. Du Pont De Nemours And Company |
N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes
|
|
US4990617A
(en)
*
|
1985-12-02 |
1991-02-05 |
E. I. Du Pont De Nemours And Company |
N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans and derivatives
|
|
US5668285A
(en)
*
|
1986-10-31 |
1997-09-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
|
|
CA2067200C
(en)
*
|
1989-10-16 |
1998-06-30 |
Kenner C. Rice |
Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
|
|
US5028612A
(en)
*
|
1990-03-22 |
1991-07-02 |
Hillel Glover |
Method for treating emotional numbness
|
|
EP1782834A3
(en)
*
|
2003-03-13 |
2007-08-01 |
Controlled Chemicals, Inc. |
Oxycodone conjugates with lower abuse potential and extended duration of action
|
|
JP2006520392A
(ja)
*
|
2003-03-13 |
2006-09-07 |
コントロールド・ケミカルズ・インコーポレーテッド |
薬物の乱用可能性を低下させ且つ作用持続時間を延長する化合物および方法
|
|
ES2357216T3
(es)
*
|
2005-06-16 |
2011-04-20 |
Mallinckrodt, Inc. |
Una ruta de síntesis de 14-hidroxil-opiáceos a través de 1-halo-tebaína o análogos.
|
|
EP2101774A2
(en)
*
|
2006-11-22 |
2009-09-23 |
Progenics Pharmaceuticals, Inc. |
7,8-saturated-4,5-epoxy-morphinanium analogs
|
|
ES2438997T5
(es)
*
|
2007-03-23 |
2024-09-03 |
SpecGx LLC |
Preparación mejorada de oximorfona a partir de oripavina
|
|
CN101711236B
(zh)
|
2007-04-12 |
2012-10-31 |
Nsab神经研究瑞典公司分公司 |
表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物
|
|
CA2684458A1
(en)
*
|
2007-04-16 |
2008-10-30 |
Mallinckrodt Inc. |
Novel opiate reduction utilizing catalytic hydrogen transfer reaction
|
|
US8252808B2
(en)
*
|
2007-12-17 |
2012-08-28 |
Mallinckrodt Llc |
Process and compounds for the production of (+)opiates
|
|
CA2709882A1
(en)
*
|
2007-12-17 |
2009-06-25 |
Peter X. Wang |
N-demethylation of n-methyl morphinans
|
|
CA2738246C
(en)
*
|
2008-09-30 |
2017-09-05 |
Mallinckrodt Inc. |
Processes for the alkylation of secondary amine groups of morphinan derivatives
|
|
US8623888B2
(en)
*
|
2009-07-15 |
2014-01-07 |
Mallinckrodt Llc |
3-oxy-hydromorphone derivatives
|