JP5000525B2 - 安定化したリン酸カルシウム複合体 - Google Patents

安定化したリン酸カルシウム複合体 Download PDF

Info

Publication number
JP5000525B2
JP5000525B2 JP2007541584A JP2007541584A JP5000525B2 JP 5000525 B2 JP5000525 B2 JP 5000525B2 JP 2007541584 A JP2007541584 A JP 2007541584A JP 2007541584 A JP2007541584 A JP 2007541584A JP 5000525 B2 JP5000525 B2 JP 5000525B2
Authority
JP
Japan
Prior art keywords
phosphopeptide
complex
ions
solution
acp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2007541584A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008521754A (ja
JP2008521754A5 (enExample
Inventor
エリック チャールズ レイノルズ,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
Original Assignee
University of Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004906762A external-priority patent/AU2004906762A0/en
Application filed by University of Melbourne filed Critical University of Melbourne
Publication of JP2008521754A publication Critical patent/JP2008521754A/ja
Publication of JP2008521754A5 publication Critical patent/JP2008521754A5/ja
Application granted granted Critical
Publication of JP5000525B2 publication Critical patent/JP5000525B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007541584A 2004-11-25 2005-11-24 安定化したリン酸カルシウム複合体 Expired - Fee Related JP5000525B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004906762A AU2004906762A0 (en) 2004-11-25 Stabilized calcium phosphate complexes
AU2004906762 2004-11-25
PCT/AU2005/001781 WO2006056013A1 (en) 2004-11-25 2005-11-24 Stabilized calcium phosphate complexes

Publications (3)

Publication Number Publication Date
JP2008521754A JP2008521754A (ja) 2008-06-26
JP2008521754A5 JP2008521754A5 (enExample) 2008-10-23
JP5000525B2 true JP5000525B2 (ja) 2012-08-15

Family

ID=36497671

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007541584A Expired - Fee Related JP5000525B2 (ja) 2004-11-25 2005-11-24 安定化したリン酸カルシウム複合体

Country Status (12)

Country Link
US (3) US8609071B2 (enExample)
EP (2) EP3192489A1 (enExample)
JP (1) JP5000525B2 (enExample)
CN (1) CN101098675B (enExample)
AU (1) AU2005309327B2 (enExample)
BR (1) BRPI0517883B8 (enExample)
CA (1) CA2589270C (enExample)
MX (1) MX2007006254A (enExample)
NZ (1) NZ555335A (enExample)
PL (1) PL1827366T3 (enExample)
RU (1) RU2404738C2 (enExample)
WO (1) WO2006056013A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007214265B2 (en) 2006-02-09 2012-06-14 The University Of Melbourne Fluoride composition and methods for dental mineralization
JP2009532065A (ja) 2006-04-05 2009-09-10 キャドバリー アダムス ユーエスエー エルエルシー 酸含有チューインガム中のリン酸カルシウム錯体
CA2648460C (en) 2006-04-05 2014-09-23 Cadbury Adams Usa Llc Calcium phosphate complex and salts in oral delivery systems
US20070237729A1 (en) 2006-04-05 2007-10-11 Cadbury Adams Usa, Llc. Impact of calcium phosphate complex on dental caries
WO2009021209A2 (en) 2007-08-09 2009-02-12 The Board Of Regents Of The University Of Texas System Bi-layered bone-like scaffolds
AU2009268528B2 (en) * 2008-07-09 2015-11-05 Board Of Regents Of The University Of Nebraska Functional micelles for hard tissue targeted delivery of chemicals
JP2010047494A (ja) * 2008-08-20 2010-03-04 Gc Corp 歯牙塗布用組成物
US9265857B2 (en) * 2010-05-11 2016-02-23 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods
WO2012145619A1 (en) * 2011-04-20 2012-10-26 University Of Rochester Nanoparticle dental composition and method of making
JP2013163656A (ja) * 2012-02-10 2013-08-22 Gc Corp 歯磨剤
US10314771B2 (en) 2013-02-28 2019-06-11 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
US9744108B2 (en) 2013-02-28 2017-08-29 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
PL3024428T3 (pl) 2013-07-23 2021-07-05 The University Of Melbourne Kompozycje i sposoby mineralizacji zębów
WO2015023773A2 (en) 2013-08-14 2015-02-19 University Of Tennessee Research Foundation Tooth remineralization compositions and methods
EP2853256A1 (en) 2013-09-25 2015-04-01 Credentis AG Dental care product for tooth whitening
ES2669548T3 (es) 2013-09-25 2018-05-28 Credentis Ag Producto de cuidado dental para el blanqueamiento de los dientes
US9168114B2 (en) 2013-10-17 2015-10-27 B & D Dental Corp. Method of making a dental prosthesis
RU2716134C2 (ru) 2013-12-24 2020-03-06 Де Юниверсити Оф Мельбурн Стабилизированные композиции на основе олова (II)
JP6751027B2 (ja) * 2014-07-11 2020-09-02 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 非晶質リン酸カルシウムを供給する口腔ケア処方システム
CA2956048C (en) 2014-07-31 2023-01-24 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
JP2016102069A (ja) * 2014-11-27 2016-06-02 株式会社ジーシー 歯面清掃方法、歯面清掃用組成物、及びその使用方法
RU2720242C2 (ru) * 2014-12-24 2020-04-28 Юниверсити Оф Мельбурн Минерализующие фторсодержащие композиции
US10219986B2 (en) 2015-03-04 2019-03-05 Modern Ideas LLC Stabilized calcium phosphate and methods of forming same
RU2745996C2 (ru) * 2015-10-26 2021-04-05 Басф Се Продукты и способы для ухода за полостью рта, содержащие гидроксиапатит-связывающие белки
US9956314B2 (en) 2016-01-26 2018-05-01 Modern Ideas LLC Adhesive for use with bone and bone-like structures
US11696879B2 (en) 2016-05-26 2023-07-11 3M Innovative Properties Company Therapeutic dental pastes and related methods and kits
US12109284B2 (en) 2016-11-08 2024-10-08 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
EA201991935A1 (ru) 2017-03-14 2020-02-14 Де Юниверсити Оф Мельбурн Комплексы для лечения чувствительности
KR102862249B1 (ko) 2017-03-14 2025-09-19 더 유니버시티 오브 멜버른 치은염을 위한 치료
CA3133097A1 (en) 2019-03-13 2020-09-17 The University Of Melbourne Compositions and methods for promoting mineralization
CN114080209A (zh) * 2019-07-04 2022-02-22 福尔顿控股公司 用于牙齿再矿化的组合物
CN110483622B (zh) * 2019-08-26 2021-06-11 无限极(中国)有限公司 酪蛋白磷酸肽及其制备方法、应用
US11154470B1 (en) 2020-07-31 2021-10-26 vVardis AG Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
EP3984517A1 (en) 2020-10-19 2022-04-20 Credentis AG Accelerating tooth remineralisation and bone regeneration with self-assembling peptides and amorphous calcium phosphate
CN112499607B (zh) * 2020-10-29 2022-07-26 南京师范大学 用于多磷酸肽富集及磷酸化位点鉴定的纳米磷酸钙的制备方法及其产品和应用
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
CN114343060B (zh) * 2021-12-30 2023-07-25 河南金丹乳酸科技股份有限公司 一种乳酸生产中提高菌体渣中蛋白含量的工艺
US20260165919A1 (en) 2022-10-28 2026-06-18 Queen Mary University Of London Toothpaste composition

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522805A (en) * 1983-06-08 1985-06-11 Norman Gordon Tooth and gum dentifrice
US5015628A (en) 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
CA1315480C (en) * 1986-06-12 1993-03-30 Eric Charles Reynolds Phosphopeptides
US6056930A (en) * 1989-05-24 2000-05-02 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US5227154A (en) 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
DK0651652T3 (da) 1992-06-29 2000-07-24 Univ Melbourne Behandling af sensitive tænder
JP3340265B2 (ja) 1994-11-21 2002-11-05 一枝 山岸 歯の漂白剤
JP4040705B2 (ja) 1996-01-24 2008-01-30 株式会社サンギ 口腔組成物
JP2975337B2 (ja) * 1997-02-20 1999-11-10 雪印乳業株式会社 カルシウム複合体
AUPO566297A0 (en) * 1997-03-13 1997-04-10 University Of Melbourne, The Calcium phosphopeptide complexes
JP3742523B2 (ja) 1998-02-27 2006-02-08 雪印乳業株式会社 高分子型カルシウム・ホスホペプチド複合体
CA2359647C (en) * 1999-03-25 2003-12-30 Warner-Lambert Company Oral care chewing gums and confections
FR2791573B1 (fr) 1999-03-30 2003-04-11 Pf Medicament Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate
US6521215B2 (en) * 1999-05-28 2003-02-18 Devin Okay Compositions and methods for tooth treatment
US6685920B2 (en) 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
GB9929919D0 (en) * 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
RU2179420C2 (ru) * 2000-05-26 2002-02-20 Иркутский государственный медицинский университет Способ профилактики кариеса зубов
JP2002338447A (ja) 2001-05-15 2002-11-27 Kuraray Co Ltd 歯科用組成物
AUPR517701A0 (en) * 2001-05-21 2001-06-14 University Of Melbourne, The Dental restorative materials
MXPA04006542A (es) * 2002-01-03 2004-10-04 Procter & Gamble Composiciones bucales estables que contienen complejos de fosfopeptido de caseina y fluooruro.
EP1461005A2 (en) * 2002-01-03 2004-09-29 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
NZ522071A (en) 2002-10-18 2005-07-29 Patrick Joseph Silcock Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
JP4340069B2 (ja) 2003-01-10 2009-10-07 雪印乳業株式会社 カルシウム複合体の製造法
US20050089481A1 (en) 2003-10-23 2005-04-28 Gc Corporation Composition for caries prevention
US20060183081A1 (en) 2004-09-27 2006-08-17 Al Bevilacqua Tooth bleaching system and method
CA2611077C (en) 2005-06-07 2014-07-15 The University Of Melbourne Dental mineralization
PL1901702T3 (pl) 2005-06-24 2015-07-31 Univ Melbourne Kompleksy jonowe

Also Published As

Publication number Publication date
CN101098675A (zh) 2008-01-02
US9814662B2 (en) 2017-11-14
RU2007123603A (ru) 2008-12-27
RU2404738C2 (ru) 2010-11-27
JP2008521754A (ja) 2008-06-26
BRPI0517883A (pt) 2008-10-21
AU2005309327B2 (en) 2010-11-25
US9295628B2 (en) 2016-03-29
EP1827366A1 (en) 2007-09-05
MX2007006254A (es) 2007-09-07
BRPI0517883B8 (pt) 2020-03-24
NZ555335A (en) 2010-10-29
EP1827366A4 (en) 2010-05-26
BRPI0517883B1 (pt) 2015-06-23
EP1827366B1 (en) 2017-03-15
US20080075675A1 (en) 2008-03-27
US8609071B2 (en) 2013-12-17
AU2005309327A1 (en) 2006-06-01
CA2589270C (en) 2014-07-15
CN101098675B (zh) 2013-04-10
WO2006056013A1 (en) 2006-06-01
US20160175226A1 (en) 2016-06-23
CA2589270A1 (en) 2006-06-01
PL1827366T3 (pl) 2017-10-31
EP3192489A1 (en) 2017-07-19
US20140079650A1 (en) 2014-03-20

Similar Documents

Publication Publication Date Title
CN101098675B (zh) 稳定的磷酸钙复合物
JP5709818B2 (ja) イオン性複合体
US12551417B2 (en) Stabilized stannous compositions
JP2019218365A (ja) 歯の石灰化のための組成物および方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080903

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080903

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20110412

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110520

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110819

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20110819

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120507

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120516

R150 Certificate of patent or registration of utility model

Ref document number: 5000525

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150525

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees