CN101098675B - 稳定的磷酸钙复合物 - Google Patents

稳定的磷酸钙复合物 Download PDF

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Publication number
CN101098675B
CN101098675B CN2005800465370A CN200580046537A CN101098675B CN 101098675 B CN101098675 B CN 101098675B CN 2005800465370 A CN2005800465370 A CN 2005800465370A CN 200580046537 A CN200580046537 A CN 200580046537A CN 101098675 B CN101098675 B CN 101098675B
Authority
CN
China
Prior art keywords
complex
solution
calcium
phosphopeptide caseinate
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2005800465370A
Other languages
English (en)
Chinese (zh)
Other versions
CN101098675A (zh
Inventor
埃里克·查尔斯·雷诺兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
Original Assignee
University of Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004906762A external-priority patent/AU2004906762A0/en
Application filed by University of Melbourne filed Critical University of Melbourne
Publication of CN101098675A publication Critical patent/CN101098675A/zh
Application granted granted Critical
Publication of CN101098675B publication Critical patent/CN101098675B/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2005800465370A 2004-11-25 2005-11-24 稳定的磷酸钙复合物 Expired - Lifetime CN101098675B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004906762A AU2004906762A0 (en) 2004-11-25 Stabilized calcium phosphate complexes
AU2004906762 2004-11-25
PCT/AU2005/001781 WO2006056013A1 (en) 2004-11-25 2005-11-24 Stabilized calcium phosphate complexes

Publications (2)

Publication Number Publication Date
CN101098675A CN101098675A (zh) 2008-01-02
CN101098675B true CN101098675B (zh) 2013-04-10

Family

ID=36497671

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800465370A Expired - Lifetime CN101098675B (zh) 2004-11-25 2005-11-24 稳定的磷酸钙复合物

Country Status (12)

Country Link
US (3) US8609071B2 (enExample)
EP (2) EP3192489A1 (enExample)
JP (1) JP5000525B2 (enExample)
CN (1) CN101098675B (enExample)
AU (1) AU2005309327B2 (enExample)
BR (1) BRPI0517883B8 (enExample)
CA (1) CA2589270C (enExample)
MX (1) MX2007006254A (enExample)
NZ (1) NZ555335A (enExample)
PL (1) PL1827366T3 (enExample)
RU (1) RU2404738C2 (enExample)
WO (1) WO2006056013A1 (enExample)

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AU2007214265B2 (en) 2006-02-09 2012-06-14 The University Of Melbourne Fluoride composition and methods for dental mineralization
JP2009532065A (ja) 2006-04-05 2009-09-10 キャドバリー アダムス ユーエスエー エルエルシー 酸含有チューインガム中のリン酸カルシウム錯体
CA2648460C (en) 2006-04-05 2014-09-23 Cadbury Adams Usa Llc Calcium phosphate complex and salts in oral delivery systems
US20070237729A1 (en) 2006-04-05 2007-10-11 Cadbury Adams Usa, Llc. Impact of calcium phosphate complex on dental caries
WO2009021209A2 (en) 2007-08-09 2009-02-12 The Board Of Regents Of The University Of Texas System Bi-layered bone-like scaffolds
AU2009268528B2 (en) * 2008-07-09 2015-11-05 Board Of Regents Of The University Of Nebraska Functional micelles for hard tissue targeted delivery of chemicals
JP2010047494A (ja) * 2008-08-20 2010-03-04 Gc Corp 歯牙塗布用組成物
US9265857B2 (en) * 2010-05-11 2016-02-23 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods
WO2012145619A1 (en) * 2011-04-20 2012-10-26 University Of Rochester Nanoparticle dental composition and method of making
JP2013163656A (ja) * 2012-02-10 2013-08-22 Gc Corp 歯磨剤
US10314771B2 (en) 2013-02-28 2019-06-11 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
US9744108B2 (en) 2013-02-28 2017-08-29 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
PL3024428T3 (pl) 2013-07-23 2021-07-05 The University Of Melbourne Kompozycje i sposoby mineralizacji zębów
WO2015023773A2 (en) 2013-08-14 2015-02-19 University Of Tennessee Research Foundation Tooth remineralization compositions and methods
EP2853256A1 (en) 2013-09-25 2015-04-01 Credentis AG Dental care product for tooth whitening
ES2669548T3 (es) 2013-09-25 2018-05-28 Credentis Ag Producto de cuidado dental para el blanqueamiento de los dientes
US9168114B2 (en) 2013-10-17 2015-10-27 B & D Dental Corp. Method of making a dental prosthesis
RU2716134C2 (ru) 2013-12-24 2020-03-06 Де Юниверсити Оф Мельбурн Стабилизированные композиции на основе олова (II)
JP6751027B2 (ja) * 2014-07-11 2020-09-02 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 非晶質リン酸カルシウムを供給する口腔ケア処方システム
CA2956048C (en) 2014-07-31 2023-01-24 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
JP2016102069A (ja) * 2014-11-27 2016-06-02 株式会社ジーシー 歯面清掃方法、歯面清掃用組成物、及びその使用方法
RU2720242C2 (ru) * 2014-12-24 2020-04-28 Юниверсити Оф Мельбурн Минерализующие фторсодержащие композиции
US10219986B2 (en) 2015-03-04 2019-03-05 Modern Ideas LLC Stabilized calcium phosphate and methods of forming same
RU2745996C2 (ru) * 2015-10-26 2021-04-05 Басф Се Продукты и способы для ухода за полостью рта, содержащие гидроксиапатит-связывающие белки
US9956314B2 (en) 2016-01-26 2018-05-01 Modern Ideas LLC Adhesive for use with bone and bone-like structures
US11696879B2 (en) 2016-05-26 2023-07-11 3M Innovative Properties Company Therapeutic dental pastes and related methods and kits
US12109284B2 (en) 2016-11-08 2024-10-08 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
EA201991935A1 (ru) 2017-03-14 2020-02-14 Де Юниверсити Оф Мельбурн Комплексы для лечения чувствительности
KR102862249B1 (ko) 2017-03-14 2025-09-19 더 유니버시티 오브 멜버른 치은염을 위한 치료
CA3133097A1 (en) 2019-03-13 2020-09-17 The University Of Melbourne Compositions and methods for promoting mineralization
CN114080209A (zh) * 2019-07-04 2022-02-22 福尔顿控股公司 用于牙齿再矿化的组合物
CN110483622B (zh) * 2019-08-26 2021-06-11 无限极（中国）有限公司 酪蛋白磷酸肽及其制备方法、应用
US11154470B1 (en) 2020-07-31 2021-10-26 vVardis AG Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
EP3984517A1 (en) 2020-10-19 2022-04-20 Credentis AG Accelerating tooth remineralisation and bone regeneration with self-assembling peptides and amorphous calcium phosphate
CN112499607B (zh) * 2020-10-29 2022-07-26 南京师范大学 用于多磷酸肽富集及磷酸化位点鉴定的纳米磷酸钙的制备方法及其产品和应用
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
CN114343060B (zh) * 2021-12-30 2023-07-25 河南金丹乳酸科技股份有限公司 一种乳酸生产中提高菌体渣中蛋白含量的工艺
US20260165919A1 (en) 2022-10-28 2026-06-18 Queen Mary University Of London Toothpaste composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
WO2002094204A1 (en) * 2001-05-21 2002-11-28 The University Of Melbourne Dental restorative materials
WO2003059303A2 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride
CN1450888A (zh) * 1999-03-25 2003-10-22 沃尼尔·朗伯公司 口腔保健用的口香糖和糖果

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US5227154A (en) 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
DK0651652T3 (da) 1992-06-29 2000-07-24 Univ Melbourne Behandling af sensitive tænder
JP3340265B2 (ja) 1994-11-21 2002-11-05 一枝 山岸 歯の漂白剤
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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
CN1450888A (zh) * 1999-03-25 2003-10-22 沃尼尔·朗伯公司 口腔保健用的口香糖和糖果
WO2002094204A1 (en) * 2001-05-21 2002-11-28 The University Of Melbourne Dental restorative materials
WO2003059303A2 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride

Also Published As

Publication number Publication date
CN101098675A (zh) 2008-01-02
US9814662B2 (en) 2017-11-14
RU2007123603A (ru) 2008-12-27
RU2404738C2 (ru) 2010-11-27
JP2008521754A (ja) 2008-06-26
BRPI0517883A (pt) 2008-10-21
AU2005309327B2 (en) 2010-11-25
US9295628B2 (en) 2016-03-29
EP1827366A1 (en) 2007-09-05
MX2007006254A (es) 2007-09-07
BRPI0517883B8 (pt) 2020-03-24
NZ555335A (en) 2010-10-29
EP1827366A4 (en) 2010-05-26
BRPI0517883B1 (pt) 2015-06-23
EP1827366B1 (en) 2017-03-15
JP5000525B2 (ja) 2012-08-15
US20080075675A1 (en) 2008-03-27
US8609071B2 (en) 2013-12-17
AU2005309327A1 (en) 2006-06-01
CA2589270C (en) 2014-07-15
WO2006056013A1 (en) 2006-06-01
US20160175226A1 (en) 2016-06-23
CA2589270A1 (en) 2006-06-01
PL1827366T3 (pl) 2017-10-31
EP3192489A1 (en) 2017-07-19
US20140079650A1 (en) 2014-03-20

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Granted publication date: 20130410