JP4851943B2 - Cxc−ケモカインレセプターリガンドおよびcc−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド - Google Patents
Cxc−ケモカインレセプターリガンドおよびcc−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド Download PDFInfo
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- JP4851943B2 JP4851943B2 JP2006547206A JP2006547206A JP4851943B2 JP 4851943 B2 JP4851943 B2 JP 4851943B2 JP 2006547206 A JP2006547206 A JP 2006547206A JP 2006547206 A JP2006547206 A JP 2006547206A JP 4851943 B2 JP4851943 B2 JP 4851943B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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| US60/531,693 | 2003-12-22 | ||
| PCT/US2004/042720 WO2005068460A1 (en) | 2003-12-22 | 2004-12-20 | Isothiazole dioxides as cxc- and cc- chemokine receptor ligands |
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| JP2007515489A JP2007515489A (ja) | 2007-06-14 |
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| JP4851943B2 true JP4851943B2 (ja) | 2012-01-11 |
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| JP2011030287A Withdrawn JP2011098984A (ja) | 2003-12-22 | 2011-02-15 | Cxc−ケモカインレセプターリガンドおよびcc−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド |
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| MY139601A (en) * | 2002-10-09 | 2009-10-30 | Schering Corp | Thiadiazoledioxides and thiadiazoleoxides as cxc-and cc-chemokine receptor ligands |
| MXPA06007076A (es) | 2003-12-19 | 2006-08-31 | Pharmacopeia Drug Discovery | Tiadiazoles como ligandos del receptor cxc y cc-quimiocina. |
| WO2005113534A2 (en) * | 2004-05-12 | 2005-12-01 | Schering Corporation | Cxcr1 and cxcr2 chemokine antagonists |
| US8071624B2 (en) | 2004-06-24 | 2011-12-06 | Incyte Corporation | N-substituted piperidines and their use as pharmaceuticals |
| GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| MX2008000366A (es) * | 2005-06-29 | 2008-03-07 | Schering Corp | Oxadiazoles di-sustituidos como ligandos del receptor cxc-quimiocina. |
| JP2009500328A (ja) * | 2005-06-29 | 2009-01-08 | シェーリング コーポレイション | Cxc−ケモカインレセプターリガンドとしての5,6−ジ−置換オキサジアゾロピラジンおよびチアジアゾロピラジン |
| RU2458051C2 (ru) * | 2005-11-24 | 2012-08-10 | ДОМПЕ ФА.Р.МА С.п.А. | (r)-арилалкиламинопроизводные и содержащие их фармацевтические композиции |
| EP1981845A2 (en) * | 2006-02-08 | 2008-10-22 | Wyeth | Sulfonamide derivatives to treat infection with hepatitis c virus |
| WO2009005801A1 (en) * | 2007-07-03 | 2009-01-08 | Schering Corporation | Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds |
| CA2695504C (en) * | 2007-08-03 | 2017-05-30 | Nucitec S.A. De C.V. | Compositions and methods for treatment and prevention of osteoarthritis |
| GB2455539B (en) * | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| JP5535931B2 (ja) | 2008-10-27 | 2014-07-02 | 武田薬品工業株式会社 | 二環性化合物 |
| EP2388252B1 (en) | 2009-01-16 | 2013-07-24 | Daiso Co., Ltd. | Process for producing 2-hydroxymethylmorpholine salt |
| EP2509596B1 (en) | 2009-12-08 | 2019-08-28 | Case Western Reserve University | Gamma aminoacids for treating ocular disorders |
| KR20130089232A (ko) | 2010-06-15 | 2013-08-09 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 안트라닐산 디아미드 유도체 |
| CN102060811A (zh) * | 2011-01-19 | 2011-05-18 | 山西大学 | 单磺酰哌嗪的合成方法 |
| US8865723B2 (en) | 2012-10-25 | 2014-10-21 | Tetra Discovery Partners Llc | Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury |
| US9763992B2 (en) | 2014-02-13 | 2017-09-19 | Father Flanagan's Boys' Home | Treatment of noise induced hearing loss |
| EP3117835A1 (en) | 2015-07-14 | 2017-01-18 | Dompé farmaceutici s.p.a. | Il-8 inhibitors for use in the treatment of certain urological disorders |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CN119264082A (zh) * | 2024-09-29 | 2025-01-07 | 中国科学技术大学 | 一种含氟呋喃基化合物、其制备方法及其应用 |
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- 2004-12-20 CA CA002550540A patent/CA2550540A1/en not_active Abandoned
- 2004-12-20 TW TW093139590A patent/TW200530231A/zh unknown
- 2004-12-20 CN CN2004800417940A patent/CN1918156B/zh not_active Expired - Fee Related
- 2004-12-20 EP EP04814856.3A patent/EP1697354B1/en not_active Expired - Lifetime
- 2004-12-20 US US11/017,505 patent/US7671212B2/en not_active Expired - Fee Related
- 2004-12-20 MX MXPA06007205A patent/MXPA06007205A/es unknown
- 2004-12-20 WO PCT/US2004/042720 patent/WO2005068460A1/en not_active Ceased
- 2004-12-20 JP JP2006547206A patent/JP4851943B2/ja not_active Expired - Fee Related
- 2004-12-21 AR ARP040104828A patent/AR046977A1/es not_active Application Discontinuation
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2007515489A (ja) | 2007-06-14 |
| JP2011098984A (ja) | 2011-05-19 |
| TW200530231A (en) | 2005-09-16 |
| US20060025453A1 (en) | 2006-02-02 |
| AR046977A1 (es) | 2006-01-04 |
| EP1697354A1 (en) | 2006-09-06 |
| CN1918156A (zh) | 2007-02-21 |
| US7671212B2 (en) | 2010-03-02 |
| WO2005068460A1 (en) | 2005-07-28 |
| MXPA06007205A (es) | 2006-08-31 |
| CA2550540A1 (en) | 2005-07-28 |
| CN1918156B (zh) | 2010-10-27 |
| EP1697354B1 (en) | 2013-08-07 |
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