JP4688678B2 - 抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用 - Google Patents

抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用 Download PDF

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Publication number
JP4688678B2
JP4688678B2 JP2005510086A JP2005510086A JP4688678B2 JP 4688678 B2 JP4688678 B2 JP 4688678B2 JP 2005510086 A JP2005510086 A JP 2005510086A JP 2005510086 A JP2005510086 A JP 2005510086A JP 4688678 B2 JP4688678 B2 JP 4688678B2
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seq
cancer
protein
sequence
amino acid
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Japanese (ja)
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JP2007536891A5 (enExample
JP2007536891A (ja
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冰 朱
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北京沙東生物技術有限公司
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2005510086A 2003-11-03 2003-11-03 抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用 Expired - Lifetime JP4688678B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2003/000928 WO2005042744A1 (en) 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use

Publications (3)

Publication Number Publication Date
JP2007536891A JP2007536891A (ja) 2007-12-20
JP2007536891A5 JP2007536891A5 (enExample) 2010-02-12
JP4688678B2 true JP4688678B2 (ja) 2011-05-25

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ID=34529378

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JP2005510086A Expired - Lifetime JP4688678B2 (ja) 2003-11-03 2003-11-03 抗癌作用を有する組換えタンパク質、それをコードする遺伝子、及びそれらの使用

Country Status (11)

Country Link
US (1) US7666989B2 (enExample)
EP (1) EP1688498B1 (enExample)
JP (1) JP4688678B2 (enExample)
CN (1) CN100549175C (enExample)
AT (1) ATE501256T1 (enExample)
AU (1) AU2003280921B2 (enExample)
BR (1) BRPI0318594B8 (enExample)
CA (1) CA2544473C (enExample)
DE (1) DE60336353D1 (enExample)
NZ (1) NZ547274A (enExample)
WO (1) WO2005042744A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761680A (zh) 2002-12-26 2006-04-19 武田药品工业株式会社 肿瘤迁移抑制素衍生物及其用途
PE20060371A1 (es) 2004-06-25 2006-06-15 Takeda Pharmaceutical Derivados de metastina en el tratamiento del cancer
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
HUE027068T2 (en) 2010-12-03 2016-08-29 Adamed Sp Zoo Anticancer fusion protein
PL219845B1 (pl) 2011-01-05 2015-07-31 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne
PL394618A1 (pl) 2011-04-19 2012-10-22 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe bialko fuzyjne
US9289468B2 (en) 2011-09-16 2016-03-22 Beijing Sunbio Biotech Co. Ltd. Fusion protein comprising circularly permuted form of trail/Apo2L, coding gene and use thereof
PL397167A1 (pl) 2011-11-28 2013-06-10 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe bialko fuzyjne
PL223487B1 (pl) 2011-12-28 2016-10-31 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100510234B1 (ko) * 1995-06-29 2005-11-25 임뮤넥스 코포레이션 세포소멸을 유도하는 시토킨
US6284236B1 (en) * 1995-06-29 2001-09-04 Immunex Corporation Cytokine that induces apoptosis
KR20010019100A (ko) 1999-08-25 2001-03-15 황규언 인간 유래 세포소멸인자 ｔｒａｉｌ의 결정화에 의한 3차원 구조
US6900185B1 (en) 2000-04-12 2005-05-31 University Of Iowa Research Foundation Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer
KR100436089B1 (ko) 2000-07-06 2004-06-14 설대우 분비성 재조합 트라이머형의 트레일 단백질 생산을 위한 디엔에이 카세트, 테트라사이클린/독시사이클린-유도성아데노-관련 바이러스 벡터, 이 둘의 조합, 및 이들을이용한 유전자 치료
CN1205335C (zh) * 2001-11-30 2005-06-08 中国人民解放军第二军医大学 肿瘤凋亡诱导配体基因、基因表达蛋白及其制备方法

Also Published As

Publication number Publication date
CA2544473A1 (en) 2005-05-12
ATE501256T1 (de) 2011-03-15
EP1688498A4 (en) 2007-06-20
WO2005042744A1 (en) 2005-05-12
BRPI0318594B1 (pt) 2017-12-26
DE60336353D1 (de) 2011-04-21
AU2003280921B2 (en) 2007-09-13
EP1688498B1 (en) 2011-03-09
EP1688498A1 (en) 2006-08-09
AU2003280921A1 (en) 2005-05-19
CA2544473C (en) 2013-08-13
HK1089788A1 (zh) 2006-12-08
CN1860229A (zh) 2006-11-08
US20080280821A1 (en) 2008-11-13
NZ547274A (en) 2009-02-28
US7666989B2 (en) 2010-02-23
CN100549175C (zh) 2009-10-14
BR0318594A (pt) 2006-10-17
BRPI0318594B8 (pt) 2021-05-25
JP2007536891A (ja) 2007-12-20

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