NZ547274A - A recombinant protein with cancer suppression action, its encoding gene and use - Google Patents

A recombinant protein with cancer suppression action, its encoding gene and use

Info

Publication number
NZ547274A
NZ547274A NZ547274A NZ54727403A NZ547274A NZ 547274 A NZ547274 A NZ 547274A NZ 547274 A NZ547274 A NZ 547274A NZ 54727403 A NZ54727403 A NZ 54727403A NZ 547274 A NZ547274 A NZ 547274A
Authority
NZ
New Zealand
Prior art keywords
seq
cancer
ser
protein
leu
Prior art date
Application number
NZ547274A
Other languages
English (en)
Inventor
Bing Zhu
Original Assignee
Sunbio Biotech Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunbio Biotech Pharmaceuticals filed Critical Sunbio Biotech Pharmaceuticals
Priority to NZ547274A priority Critical patent/NZ547274A/en
Publication of NZ547274A publication Critical patent/NZ547274A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NZ547274A 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use NZ547274A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ547274A NZ547274A (en) 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ547274A NZ547274A (en) 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use
PCT/CN2003/000928 WO2005042744A1 (en) 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use

Publications (1)

Publication Number Publication Date
NZ547274A true NZ547274A (en) 2009-02-28

Family

ID=34529378

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ547274A NZ547274A (en) 2003-11-03 2003-11-03 A recombinant protein with cancer suppression action, its encoding gene and use

Country Status (11)

Country Link
US (1) US7666989B2 (enExample)
EP (1) EP1688498B1 (enExample)
JP (1) JP4688678B2 (enExample)
CN (1) CN100549175C (enExample)
AT (1) ATE501256T1 (enExample)
AU (1) AU2003280921B2 (enExample)
BR (1) BRPI0318594B8 (enExample)
CA (1) CA2544473C (enExample)
DE (1) DE60336353D1 (enExample)
NZ (1) NZ547274A (enExample)
WO (1) WO2005042744A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761680A (zh) 2002-12-26 2006-04-19 武田药品工业株式会社 肿瘤迁移抑制素衍生物及其用途
PE20060371A1 (es) 2004-06-25 2006-06-15 Takeda Pharmaceutical Derivados de metastina en el tratamiento del cancer
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
HUE027068T2 (en) 2010-12-03 2016-08-29 Adamed Sp Zoo Anticancer fusion protein
PL219845B1 (pl) 2011-01-05 2015-07-31 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne
PL394618A1 (pl) 2011-04-19 2012-10-22 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe bialko fuzyjne
US9289468B2 (en) 2011-09-16 2016-03-22 Beijing Sunbio Biotech Co. Ltd. Fusion protein comprising circularly permuted form of trail/Apo2L, coding gene and use thereof
PL397167A1 (pl) 2011-11-28 2013-06-10 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe bialko fuzyjne
PL223487B1 (pl) 2011-12-28 2016-10-31 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100510234B1 (ko) * 1995-06-29 2005-11-25 임뮤넥스 코포레이션 세포소멸을 유도하는 시토킨
US6284236B1 (en) * 1995-06-29 2001-09-04 Immunex Corporation Cytokine that induces apoptosis
KR20010019100A (ko) 1999-08-25 2001-03-15 황규언 인간 유래 세포소멸인자 trail의 결정화에 의한 3차원 구조
US6900185B1 (en) 2000-04-12 2005-05-31 University Of Iowa Research Foundation Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer
KR100436089B1 (ko) 2000-07-06 2004-06-14 설대우 분비성 재조합 트라이머형의 트레일 단백질 생산을 위한 디엔에이 카세트, 테트라사이클린/독시사이클린-유도성아데노-관련 바이러스 벡터, 이 둘의 조합, 및 이들을이용한 유전자 치료
CN1205335C (zh) * 2001-11-30 2005-06-08 中国人民解放军第二军医大学 肿瘤凋亡诱导配体基因、基因表达蛋白及其制备方法

Also Published As

Publication number Publication date
CA2544473A1 (en) 2005-05-12
ATE501256T1 (de) 2011-03-15
EP1688498A4 (en) 2007-06-20
WO2005042744A1 (en) 2005-05-12
BRPI0318594B1 (pt) 2017-12-26
DE60336353D1 (de) 2011-04-21
AU2003280921B2 (en) 2007-09-13
EP1688498B1 (en) 2011-03-09
EP1688498A1 (en) 2006-08-09
AU2003280921A1 (en) 2005-05-19
CA2544473C (en) 2013-08-13
HK1089788A1 (zh) 2006-12-08
CN1860229A (zh) 2006-11-08
US20080280821A1 (en) 2008-11-13
US7666989B2 (en) 2010-02-23
CN100549175C (zh) 2009-10-14
JP4688678B2 (ja) 2011-05-25
BR0318594A (pt) 2006-10-17
BRPI0318594B8 (pt) 2021-05-25
JP2007536891A (ja) 2007-12-20

Similar Documents

Publication Publication Date Title
CN108137671B (zh) 可溶性pdl-1分子
AU2003280921B2 (en) A recombinant protein with cancer suppression action, its encoding gene and use
CN114380919B (zh) 经修饰的il-2分子及其用途
JP2015533838A (ja) rTRAIL突然変異体およびそのモノメチルアウリスタチンEコンジュゲート
WO2021037160A1 (zh) 肿瘤酶响应型重组焦亡蛋白递药系统及其抗肿瘤用途
RU2333221C2 (ru) Рекомбинантный белок, обладающий противораковым действием, кодирующий его ген и его применение
KR101185310B1 (ko) 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
JP4955654B2 (ja) 癌の治療のためのp21タンパク質を含んで成るコンジュゲート
JPWO1999014325A1 (ja) 新規Fasリガンド誘導体
CN109400711B (zh) 一种PDGFRβ靶向性肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
KR101273893B1 (ko) 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
KR100863060B1 (ko) 암 억제 활동을 하는 재조합 단백질, 그 암호화 유전자 및 재조합 단백질을 활성성분으로 포함하는 암치료용 약학적 조성물
KR20110043485A (ko) 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
MXPA06004932A (en) A recombinant protein with cancer suppression action, its encoding gene and use
ZA200604478B (en) A recombinant protein with cancer suppression action, its encoding gene and uses thereof
Sun et al. TRAIL mutant membrane penetrating peptide alike-MuR6-TR enhances the antitumor effects of TRAIL in pancreatic carcinoma both in vitro and in vivo
JP6105623B2 (ja) 核内因子κB活性化受容体(RANK)をターゲティングするペプチドおよびそれらの適用
CN104640557A (zh) 骨保护素衍生的组合物及其用途
HK1089788B (en) A recombinant protein with cancer suppression action, its encoding gene and use

Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: SUNBIO BIOTECH PHARMACEUTICALS (TIANJIN) CO., CN

Free format text: OLD OWNER(S): BEIJING SUNBIO BIOTECH CO., LTD

PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: BEIJING SUNBIO BIOTECH CO., CN

Free format text: OLD OWNER(S): SUNBIO BIOTECH PHARMACEUTICALS (TIANJIN) CO., LTD

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 03 NOV 2016 BY CPA GLOBAL

Effective date: 20130919

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2017 BY CPA GLOBAL

Effective date: 20160923

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2018 BY CPA GLOBAL

Effective date: 20170929

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2019 BY CPA GLOBAL

Effective date: 20180920

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2020 BY CPA GLOBAL

Effective date: 20190919

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2021 BY CPA GLOBAL

Effective date: 20200917

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2022 BY CPA GLOBAL

Effective date: 20210916

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 NOV 2023 BY CPA GLOBAL

Effective date: 20220923

EXPY Patent expired