JP4467649B2 - 血液製剤の改良された貯蔵および保存法 - Google Patents
血液製剤の改良された貯蔵および保存法 Download PDFInfo
- Publication number
- JP4467649B2 JP4467649B2 JP54369498A JP54369498A JP4467649B2 JP 4467649 B2 JP4467649 B2 JP 4467649B2 JP 54369498 A JP54369498 A JP 54369498A JP 54369498 A JP54369498 A JP 54369498A JP 4467649 B2 JP4467649 B2 JP 4467649B2
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- Prior art keywords
- carnitine
- blood
- rbc
- red blood
- membrane
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Images
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- A61L2202/20—Targets to be treated
- A61L2202/22—Blood or products thereof
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- External Artificial Organs (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Packages (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/840,765 | 1997-04-16 | ||
| US08/840,765 US6482585B2 (en) | 1997-04-16 | 1997-04-16 | Storage and maintenance of blood products including red blood cells and platelets |
| PCT/IT1998/000086 WO1998046073A1 (en) | 1997-04-16 | 1998-04-15 | Improved storage and maintenance of blood products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001523225A JP2001523225A (ja) | 2001-11-20 |
| JP2001523225A5 JP2001523225A5 (enExample) | 2005-11-24 |
| JP4467649B2 true JP4467649B2 (ja) | 2010-05-26 |
Family
ID=25283169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54369498A Expired - Lifetime JP4467649B2 (ja) | 1997-04-16 | 1998-04-15 | 血液製剤の改良された貯蔵および保存法 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6482585B2 (enExample) |
| EP (1) | EP0975214B1 (enExample) |
| JP (1) | JP4467649B2 (enExample) |
| KR (1) | KR100508408B1 (enExample) |
| CN (2) | CN1698430A (enExample) |
| AT (1) | ATE257326T1 (enExample) |
| AU (1) | AU739842B2 (enExample) |
| BR (1) | BR9808911B1 (enExample) |
| CA (1) | CA2286721A1 (enExample) |
| CZ (1) | CZ298671B6 (enExample) |
| DE (1) | DE69821002T2 (enExample) |
| DK (1) | DK0975214T3 (enExample) |
| ES (1) | ES2212288T3 (enExample) |
| HU (1) | HUP0001936A3 (enExample) |
| IL (1) | IL132271A (enExample) |
| NZ (1) | NZ500534A (enExample) |
| PL (1) | PL192684B1 (enExample) |
| PT (1) | PT975214E (enExample) |
| SK (1) | SK284688B6 (enExample) |
| WO (1) | WO1998046073A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
| US6403124B1 (en) * | 1997-04-16 | 2002-06-11 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
| KR100642731B1 (ko) * | 1999-10-11 | 2006-11-03 | 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. | 의료용 용액에서 삼투제로서 ｌ-카르니틴 및 그의알카노일 유도체의 용도 |
| US8828226B2 (en) | 2003-03-01 | 2014-09-09 | The Trustees Of Boston University | System for assessing the efficacy of stored red blood cells using microvascular networks |
| RU2245145C1 (ru) * | 2003-10-01 | 2005-01-27 | Российский государственный медицинский университет | Средство нормализации агрегационных свойств тромбоцитов и эритроцитов и морфоденситометрических характеристик эритроцитов |
| DE602004031033D1 (de) * | 2003-10-09 | 2011-02-24 | Core Dynamics Ltd | Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel |
| WO2005072523A2 (en) * | 2004-02-02 | 2005-08-11 | I.M.T. Interface Multigrad Technology Ltd. | Biological material and methods and solutions for preservation thereof |
| US8196416B2 (en) * | 2004-02-02 | 2012-06-12 | Core Dynamics Limited | Device for directional cooling of biological matter |
| WO2005120591A1 (en) * | 2004-06-07 | 2005-12-22 | I.M.T. Interface Multigrad Technology Ltd. | Method for sterilization of biological preparations |
| EP1778007A1 (en) * | 2004-08-12 | 2007-05-02 | I.M.T. Interface Multigrad Technology Ltd. | Method and apparatus for freezing or thawing of a biological material |
| US20080160496A1 (en) * | 2005-02-22 | 2008-07-03 | Victor Rzepakovsky | Preserved Viable Cartilage, Method for Its Preservation, and System and Devices Used Therefor |
| FR2884717B1 (fr) * | 2005-04-25 | 2009-07-03 | Erytech Pharma Soc Par Actions | Erythrocytes renfermant de l'arginine deiminase |
| EP1909565A2 (en) * | 2005-08-03 | 2008-04-16 | Interface Multigrad Technology (IMT) Ltd. | Somatic cells for use in cell therapy |
| US7462485B2 (en) * | 2005-10-07 | 2008-12-09 | Glaser Lawrence F | Modified erythrocytes and uses thereof |
| US8835104B2 (en) | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| US20090202978A1 (en) * | 2008-02-13 | 2009-08-13 | Ginadi Shaham | Method and apparatus for freezing of a biological material |
| US8871434B2 (en) * | 2008-03-21 | 2014-10-28 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US8968992B2 (en) * | 2008-03-21 | 2015-03-03 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| JP6199557B2 (ja) | 2009-10-12 | 2017-09-20 | ニュー ヘルス サイエンシーズ、インク．Ｎｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． | 酸素及び二酸化炭素の減損能力をもつ血液保存袋システム及び減損装置 |
| US12089589B2 (en) | 2009-10-12 | 2024-09-17 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| CN102905522A (zh) | 2009-10-12 | 2013-01-30 | 新健康科学股份有限公司 | 用于从红细胞中除去氧的氧消耗装置和方法 |
| US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| WO2011049709A1 (en) | 2009-10-23 | 2011-04-28 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
| PT2608816T (pt) | 2010-08-25 | 2023-10-12 | Dartmouth College | Método para melhorar a qualidade e a sobrevivência dos glóbulos vermelhos durante o armazenamento |
| JP5859558B2 (ja) * | 2010-11-05 | 2016-02-10 | ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． | 赤血球の照射及び嫌気性保存 |
| EP2645854B1 (en) | 2010-11-29 | 2017-10-18 | New York Blood Center, Inc. | Method of blood pooling and storage |
| US9067004B2 (en) | 2011-03-28 | 2015-06-30 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
| WO2012139017A1 (en) | 2011-04-07 | 2012-10-11 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| CN103732056B (zh) * | 2011-07-05 | 2016-08-17 | 新健康科学股份有限公司 | 用于红细胞之延长贮藏的系统及使用方法 |
| EP4074395B1 (en) | 2011-08-10 | 2024-01-24 | Hemanext Inc. | Integrated leukocyte, oxygen and/or co2 depletion, and plasma separation filter device |
| EP3967143B1 (en) | 2013-02-28 | 2025-05-21 | Hemanext Inc. | Gas addition device for blood treatment and corresponding method |
| EP3268015B1 (en) | 2015-03-10 | 2021-10-13 | Hemanext Inc. | Oxygen reduction disposable kits, devices and methods of use thereof |
| KR102661405B1 (ko) | 2015-04-23 | 2024-04-25 | 헤마넥스트 인코포레이티드 | 혐기성 혈액 저장 용기 |
| CA2985799A1 (en) | 2015-05-18 | 2016-11-24 | New Health Sciences, Inc. | Methods for the storage of whole blood, and compositions thereof |
| AU2017271545C1 (en) | 2016-05-27 | 2023-06-15 | Hemanext Inc. | Anaerobic blood storage and pathogen inactivation method |
| DE102017218847A1 (de) | 2017-10-23 | 2019-04-25 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Verbesserung der Stabilität von Blut und Blutprodukten |
| EP4064837A4 (en) * | 2019-11-29 | 2023-01-04 | Rutgers, the State University of New Jersey | COMPOSITIONS, KITS AND METHODS FOR STORING BLOOD PRODUCTS AND METHODS OF USE THEREOF |
| CN116115753A (zh) * | 2021-11-15 | 2023-05-16 | 上海循曜生物科技有限公司 | 一种新的改善血小板质量的方法 |
| CN114600872A (zh) | 2022-04-13 | 2022-06-10 | 西安北光医学生物技术有限公司 | 一种细胞、组织或器官的抗损伤保存的方法及保存系统 |
| AU2024244509A1 (en) * | 2023-03-31 | 2025-10-02 | Hemerus Medical, Llc | Formulations and methods for collecting and storing blood and blood products |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3729947A (en) * | 1970-12-04 | 1973-05-01 | Alza Corp | Process for storing blood platelets |
| US3792947A (en) * | 1972-07-10 | 1974-02-19 | A Diehl | Molding apparatus |
| EP0083778B1 (de) * | 1982-01-07 | 1987-11-11 | Fresenius AG | Aufbewahrungsbeutel |
| US4613322A (en) * | 1982-12-08 | 1986-09-23 | Edelson Richard Leslie | Method and system for externally treating the blood |
| US5149682A (en) * | 1987-09-11 | 1992-09-22 | W. R. Grace & Co. -Conn. | Manufacturing method for superconducting ceramics and products thereof |
| US5232844A (en) * | 1990-05-15 | 1993-08-03 | New York Blood Center | Photodynamic inactivation of viruses in cell-containing compositions |
| US5120649A (en) * | 1990-05-15 | 1992-06-09 | New York Blood Center, Inc. | Photodynamic inactivation of viruses in blood cell-containing compositions |
| US5376524A (en) | 1991-04-01 | 1994-12-27 | Thomas Jefferson University | Platelet storage medium containing acetate and phosphate |
| IT1261695B (it) * | 1993-06-02 | 1996-05-29 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
| US5362442A (en) * | 1993-07-22 | 1994-11-08 | 2920913 Canada Inc. | Method for sterilizing products with gamma radiation |
| AU6267496A (en) * | 1995-06-07 | 1996-12-30 | Steritech, Inc. | Methods of inactivating leukocytes and inhibiting cytokine p roduction in blood products |
| WO1997016967A1 (en) * | 1995-11-09 | 1997-05-15 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for promoting blood component survival |
| IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
| US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
| US6010890A (en) * | 1997-04-29 | 2000-01-04 | New York Blood Center, Inc. | Method for viral inactivation and compositions for use in same |
-
1997
- 1997-04-16 US US08/840,765 patent/US6482585B2/en not_active Expired - Fee Related
-
1998
- 1998-04-15 BR BRPI9808911-0A patent/BR9808911B1/pt not_active IP Right Cessation
- 1998-04-15 HU HU0001936A patent/HUP0001936A3/hu unknown
- 1998-04-15 SK SK1427-99A patent/SK284688B6/sk not_active IP Right Cessation
- 1998-04-15 AU AU70781/98A patent/AU739842B2/en not_active Ceased
- 1998-04-15 PL PL336294A patent/PL192684B1/pl not_active IP Right Cessation
- 1998-04-15 NZ NZ500534A patent/NZ500534A/en not_active IP Right Cessation
- 1998-04-15 PT PT98917604T patent/PT975214E/pt unknown
- 1998-04-15 CN CNA2005100674289A patent/CN1698430A/zh active Pending
- 1998-04-15 CZ CZ0368199A patent/CZ298671B6/cs not_active IP Right Cessation
- 1998-04-15 KR KR10-1999-7009554A patent/KR100508408B1/ko not_active Expired - Fee Related
- 1998-04-15 CA CA002286721A patent/CA2286721A1/en not_active Abandoned
- 1998-04-15 AT AT98917604T patent/ATE257326T1/de active
- 1998-04-15 DK DK98917604T patent/DK0975214T3/da active
- 1998-04-15 EP EP98917604A patent/EP0975214B1/en not_active Expired - Lifetime
- 1998-04-15 IL IL13227198A patent/IL132271A/xx not_active IP Right Cessation
- 1998-04-15 CN CN98804212A patent/CN1252687A/zh active Pending
- 1998-04-15 JP JP54369498A patent/JP4467649B2/ja not_active Expired - Lifetime
- 1998-04-15 WO PCT/IT1998/000086 patent/WO1998046073A1/en not_active Ceased
- 1998-04-15 DE DE69821002T patent/DE69821002T2/de not_active Expired - Lifetime
- 1998-04-15 ES ES98917604T patent/ES2212288T3/es not_active Expired - Lifetime
-
2002
- 2002-08-01 US US10/208,834 patent/US6960428B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4467649B2 (ja) | 血液製剤の改良された貯蔵および保存法 | |
| US7851142B2 (en) | Method of reducing glycolysis in platelet concentrates using L-carnitine, alkanoyl carnitines and salts thereof | |
| HK1083720A (en) | Improved storage and maintenance of blood products | |
| HK1025477B (en) | Improved storage and maintenance of blood products |
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