DE602004031033D1 - Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel - Google Patents
Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpelInfo
- Publication number
- DE602004031033D1 DE602004031033D1 DE602004031033T DE602004031033T DE602004031033D1 DE 602004031033 D1 DE602004031033 D1 DE 602004031033D1 DE 602004031033 T DE602004031033 T DE 602004031033T DE 602004031033 T DE602004031033 T DE 602004031033T DE 602004031033 D1 DE602004031033 D1 DE 602004031033D1
- Authority
- DE
- Germany
- Prior art keywords
- cartilage
- defrosting
- transplanting
- viable
- vital body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Meat, Egg Or Seafood Products (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50954603P | 2003-10-09 | 2003-10-09 | |
US53650804P | 2004-01-15 | 2004-01-15 | |
PCT/IL2004/000929 WO2005032251A1 (en) | 2003-10-09 | 2004-10-10 | Method for freezing, thawing and transplantation of viable cartilage |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004031033D1 true DE602004031033D1 (de) | 2011-02-24 |
Family
ID=34426097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004031033T Active DE602004031033D1 (de) | 2003-10-09 | 2004-10-10 | Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070077237A1 (de) |
EP (1) | EP1677594B1 (de) |
AT (1) | ATE494777T1 (de) |
DE (1) | DE602004031033D1 (de) |
WO (1) | WO2005032251A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005072523A2 (en) * | 2004-02-02 | 2005-08-11 | I.M.T. Interface Multigrad Technology Ltd. | Biological material and methods and solutions for preservation thereof |
WO2005072790A1 (en) * | 2004-02-02 | 2005-08-11 | I.M.T. Interface Multigrad Technology Ltd. | Device for directional cooling of biological matter |
WO2005120591A1 (en) * | 2004-06-07 | 2005-12-22 | I.M.T. Interface Multigrad Technology Ltd. | Method for sterilization of biological preparations |
EP1778007A1 (de) | 2004-08-12 | 2007-05-02 | I.M.T. Interface Multigrad Technology Ltd. | Verfahren und gerät zum einfrieren bzw. auftauen von biologischem material |
EP1850661A2 (de) * | 2005-02-22 | 2007-11-07 | Interface Multigrad Technology (IMT) Ltd. | Konservierter lebensfähiger knorpel, verfahren zu seiner konservierung, sowie hierfür verwendete(s) system und geräte |
WO2007015252A2 (en) * | 2005-08-03 | 2007-02-08 | I.M.T. Interface Multigrad Technology Ltd. | Somatic cells for use in cell therapy |
US20090202978A1 (en) * | 2008-02-13 | 2009-08-13 | Ginadi Shaham | Method and apparatus for freezing of a biological material |
MX2015000460A (es) | 2012-07-11 | 2015-07-06 | Osiris Therapeutics Inc | Productos de cartilago alterados. |
WO2014130883A2 (en) | 2013-02-22 | 2014-08-28 | Allosource | Cartilage mosaic compositions and methods |
KR102312720B1 (ko) | 2013-03-15 | 2021-10-13 | 알로소스 | 연조직 회복 및 재생을 위한 세포 재배치된 콜라겐 매트릭스 |
WO2014151939A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Perforated osteochondral allograft compositions |
US20150344847A1 (en) * | 2014-05-29 | 2015-12-03 | Vivex Biomedical Inc. | Method For Production Of Large Numbers Of Cartilage Cells With Phenotype Retention |
WO2018104935A1 (en) * | 2016-12-06 | 2018-06-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Cryopreservation method of biological specimen |
EP4181675A4 (de) | 2020-07-18 | 2024-04-24 | Ossium Health Inc | Permeation ganzer wirbelkörper mit einem kryoschutzmittel mittels vakuumgestützter diffusion |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3074247A (en) * | 1960-04-25 | 1963-01-22 | Texstar Corp | Methods and apparatus for use in freezing packaged products |
US3347745A (en) * | 1963-12-06 | 1967-10-17 | Union Carbide Corp | Process for freezing erythrocytes |
US4018911A (en) * | 1975-11-10 | 1977-04-19 | The United States Of America As Represented By The Secretary Of The Navy | Method for large volume freezing and thawing of packed erythrocytes |
US4117881A (en) * | 1977-06-14 | 1978-10-03 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | System for and method of freezing biological tissue |
JPS6056B2 (ja) * | 1983-01-14 | 1985-01-05 | 株式会社 ほくさん | 受精卵、精子等の凍結装置 |
US4620908A (en) * | 1983-10-03 | 1986-11-04 | Biocell Laboratories, Inc. | Method for destroying microbial contamination in protein materials |
US4857319A (en) * | 1985-01-11 | 1989-08-15 | The Regents Of The University Of California | Method for preserving liposomes |
US5071598A (en) * | 1987-12-03 | 1991-12-10 | California Institute Of Technology | Cryoprotective reagent |
US6007978A (en) * | 1988-05-18 | 1999-12-28 | Cobe Laboratories, Inc. | Method of freezing cells and cell-like materials |
US4874690A (en) * | 1988-08-26 | 1989-10-17 | Cryopharm Corporation | Lyophilization of red blood cells |
US5059518A (en) * | 1988-10-20 | 1991-10-22 | Coulter Corporation | Stabilized lyophilized mammalian cells and method of making same |
US5131850A (en) * | 1989-11-03 | 1992-07-21 | Cryolife, Inc. | Method for cryopreserving musculoskeletal tissues |
US5418130A (en) * | 1990-04-16 | 1995-05-23 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
US5587490A (en) * | 1990-04-16 | 1996-12-24 | Credit Managers Association Of California | Method of inactivation of viral and bacterial blood contaminants |
CA2051092C (en) * | 1990-09-12 | 2002-07-23 | Stephen A. Livesey | Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions |
US20040067157A1 (en) * | 1993-07-22 | 2004-04-08 | Clearant, Inc. | Methods for sterilizing biological materials |
US6319914B1 (en) * | 1993-11-05 | 2001-11-20 | Apollo Biopharmaceuticals, Inc. | Cytoprotective effect of polycyclic phenolic compounds |
US6146890A (en) * | 1994-07-03 | 2000-11-14 | Danon; David | Method and system for cultivating macrophages |
US5709992A (en) * | 1994-08-17 | 1998-01-20 | Rubinstein; Alan I. | Method for disinfecting red blood cells |
US5869092A (en) * | 1995-01-05 | 1999-02-09 | The Regents Of The University Of California | Prevention of leakage and phase separation during thermotropic phase transition in liposomes and biological cells |
CA2146098A1 (en) * | 1995-01-12 | 1996-07-13 | Ray V. Rajotte | Bulk cryopreservation of biological materials and uses for cryopreserved and encapsulated biological materials |
US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US5629145A (en) * | 1995-03-24 | 1997-05-13 | Organ, Inc. | Cryopreservation of cell suspensions |
US5897987A (en) * | 1996-03-25 | 1999-04-27 | Advanced Reproduction Technologies, Inc. | Use of arabinogalactan in cell cryopreservation media |
US6743575B2 (en) * | 1996-06-14 | 2004-06-01 | Biostore New Zealand Ltd. | Compositions and methods for the preservation of living tissues |
US5873254A (en) * | 1996-09-06 | 1999-02-23 | Interface Multigrad Technology | Device and methods for multigradient directional cooling and warming of biological samples |
US5827741A (en) * | 1996-11-19 | 1998-10-27 | The Regents Of The University Of California | Cryopreservation of human adult and fetal pancreatic cells and human platelets |
US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
US5955257A (en) * | 1997-10-21 | 1999-09-21 | Regents Of The University Of Minnesota | Infusible grade short-term cell storage medium for mononuclear cells |
US6337205B1 (en) * | 1998-01-06 | 2002-01-08 | Integrated Biosystems, Inc | Cryopreservation vial apparatus and methods |
US6962698B1 (en) * | 1998-02-17 | 2005-11-08 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
US6073540A (en) * | 1998-11-10 | 2000-06-13 | Fmc Corporation | Apparatus for heating or cooling product containers |
US6194137B1 (en) * | 1999-04-13 | 2001-02-27 | Organ Recovery Systems, Inc. | Method of cryopreservation of blood vessels by vitrification |
US20050020524A1 (en) * | 1999-04-15 | 2005-01-27 | Monash University | Hematopoietic stem cell gene therapy |
WO2001058266A1 (en) * | 2000-02-10 | 2001-08-16 | The Regents Of The University Of California | Therapeutic platelets and methods |
US6488033B1 (en) * | 2000-05-15 | 2002-12-03 | Cryolife, Inc. | Osteochondral transplant techniques |
AU1179202A (en) * | 2000-10-19 | 2002-04-29 | Organ Recovery Systems | Method of cryopreservation of tissues or organs other than a blood vessel by vitrification |
US7560280B2 (en) * | 2000-11-03 | 2009-07-14 | Kourion Therapeutics Gmbh | Human cord blood derived unrestricted somatic stem cells (USSC) |
JP5013152B2 (ja) * | 2001-02-28 | 2012-08-29 | 株式会社ビーエムジー | 蛋白質複合体形成剤 |
US6945056B2 (en) * | 2001-11-01 | 2005-09-20 | Integrated Biosystems, Inc. | Systems and methods for freezing, mixing and thawing biopharmaceutical material |
US6453683B1 (en) * | 2001-05-22 | 2002-09-24 | Integrated Biosystems, Inc. | Tapered slot cryopreservation system with controlled dendritic freezing front velocity |
US6698213B2 (en) * | 2001-05-22 | 2004-03-02 | Integrated Biosystems, Inc. | Systems and methods for freezing and storing biopharmaceutical material |
US6916602B2 (en) * | 2001-05-29 | 2005-07-12 | Interface Multigrad Technology Ltd. | Methods of preserving functionality of an ovary, preserving fertility of a patient undergoing a treatment expected to cause sterility and assuring a supply of viable gametes for future use |
US20030068416A1 (en) * | 2001-09-24 | 2003-04-10 | Wilson Burgess | Method of lyophylization to reduce solvent content and enhance product recovery |
US20030059338A1 (en) * | 2001-09-24 | 2003-03-27 | Mann David M. | Methods for sterilizing biological materials using flavonoid/flavonol stabilizers |
US20050095228A1 (en) * | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
FR2833271B1 (fr) * | 2001-12-10 | 2004-09-17 | Coletica | Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles |
JP2003189875A (ja) * | 2001-12-28 | 2003-07-08 | Japan Science & Technology Corp | 膵β細胞関連転写因子の遺伝子導入によるインスリン産生細胞の形成誘導 |
EP1476013B1 (de) * | 2002-01-08 | 2011-05-11 | Core Dynamics Limited | Verfahren und gerät für das einfrieren und auftauen von biologischen proben |
AU2003207980A1 (en) * | 2002-06-27 | 2004-01-19 | I.M.T. Interface Multigrad Technology Ltd. | Changing the temperature of a liquid sample and a receptacle useful therefor |
ATE542123T1 (de) * | 2002-06-27 | 2012-02-15 | Core Dynamics Ltd | Verbessertes verfahren zum einfrieren lebensfähiger zellen |
US20040197310A1 (en) * | 2003-02-12 | 2004-10-07 | Sanberg Paul R. | Compositions and methods for using umbilical cord progenitor cells in the treatment of myocardial infarction |
ZA200404101B (en) * | 2003-05-26 | 2005-03-07 | Reliance Life Sciences Pvt Ltd | In vitro culture of Mesenchymal Stem Cells (MSC) and a process for the preparation thereof for therapeutic use. |
ES2428769T3 (es) * | 2003-09-16 | 2013-11-11 | Bredent Dentalgeräte Und Materialien Fach- Und Organisationsberatung Peter Brehm | Tornillo de posicionado para la preparación de dientes artificiales en maxilares sin dientes o parcialmente con dientes |
TWI338714B (en) * | 2003-12-02 | 2011-03-11 | Cathay General Hospital | Method of isolation and enrichment of mesenchymal stem cells from amniotic fluid |
EP1778007A1 (de) * | 2004-08-12 | 2007-05-02 | I.M.T. Interface Multigrad Technology Ltd. | Verfahren und gerät zum einfrieren bzw. auftauen von biologischem material |
US20060035383A1 (en) * | 2004-08-12 | 2006-02-16 | David Ho | Dry platelet preparations for use in diagnostics |
-
2004
- 2004-10-10 DE DE602004031033T patent/DE602004031033D1/de active Active
- 2004-10-10 AT AT04770599T patent/ATE494777T1/de not_active IP Right Cessation
- 2004-10-10 EP EP04770599A patent/EP1677594B1/de not_active Not-in-force
- 2004-10-10 US US10/575,558 patent/US20070077237A1/en not_active Abandoned
- 2004-10-10 WO PCT/IL2004/000929 patent/WO2005032251A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2005032251A1 (en) | 2005-04-14 |
ATE494777T1 (de) | 2011-01-15 |
US20070077237A1 (en) | 2007-04-05 |
EP1677594B1 (de) | 2011-01-12 |
EP1677594A1 (de) | 2006-07-12 |
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