FR2833271B1 - Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles - Google Patents
Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modelesInfo
- Publication number
- FR2833271B1 FR2833271B1 FR0115942A FR0115942A FR2833271B1 FR 2833271 B1 FR2833271 B1 FR 2833271B1 FR 0115942 A FR0115942 A FR 0115942A FR 0115942 A FR0115942 A FR 0115942A FR 2833271 B1 FR2833271 B1 FR 2833271B1
- Authority
- FR
- France
- Prior art keywords
- production
- models
- monolayers
- monocytes
- cellular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 title 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 230000001413 cellular effect Effects 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 210000001616 monocyte Anatomy 0.000 title 1
- 239000000725 suspension Substances 0.000 title 1
- 238000013334 tissue model Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
- C12N5/064—Immunosuppressive dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/25—Tumour necrosing factors [TNF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/04—Screening or testing on artificial tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/04—Screening or testing on artificial tissues
- C12N2503/06—Screening or testing on artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0115942A FR2833271B1 (fr) | 2001-12-10 | 2001-12-10 | Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles |
JP2003551293A JP2005518787A (ja) | 2001-12-10 | 2002-12-10 | invitroにおけるCD14陽性単球からの樹状細胞の産出 |
GB0412968A GB2399347B (en) | 2001-12-10 | 2002-12-10 | In Vitro production of Dendritic cells from CD14+Monocytes |
PCT/EP2002/014874 WO2003050271A2 (fr) | 2001-12-10 | 2002-12-10 | Production in vitro de cellules dendritiques a partir de monocytes cd14+ en particulier pour la preparation de modeles tissulaires et/ou cellulaires monocouches et tridimensionnels, ainsi que l'utilisation de ces modeles |
KR1020047008890A KR100870521B1 (ko) | 2001-12-10 | 2002-12-10 | Cd14+ 단핵세포로부터 수상돌기세포의 생체외 생성 |
DE10297513.2T DE10297513C5 (de) | 2001-12-10 | 2002-12-10 | In vitro Herstellung von dendritischen Zellen aus CD14+ Monocyten |
CA2469792A CA2469792C (fr) | 2001-12-10 | 2002-12-10 | Production in vitro de cellules dendritiques a partir de monocytes cd14+en particulier pour la preparation de modeles tissulaires ou cellulairesen suspension, monocouches et tridimensionnels, ainsi que l'utilisation de ces modeles |
US10/496,879 US20050008623A1 (en) | 2001-12-10 | 2002-12-10 | In vitro production of dendritic cells from CD14+ monocytes |
AU2002366532A AU2002366532A1 (en) | 2001-12-10 | 2002-12-10 | In vitro production of dendritic cells from cd14+ monocytes |
JP2009098970A JP5101559B2 (ja) | 2001-12-10 | 2009-04-15 | invitroにおけるCD14陽性単球からの樹状細胞の産出 |
JP2009098971A JP5209566B2 (ja) | 2001-12-10 | 2009-04-15 | invitroにおけるCD14陽性単球からの樹状細胞の産出 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0115942A FR2833271B1 (fr) | 2001-12-10 | 2001-12-10 | Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2833271A1 FR2833271A1 (fr) | 2003-06-13 |
FR2833271B1 true FR2833271B1 (fr) | 2004-09-17 |
Family
ID=8870300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0115942A Expired - Lifetime FR2833271B1 (fr) | 2001-12-10 | 2001-12-10 | Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles |
Country Status (9)
Country | Link |
---|---|
US (1) | US20050008623A1 (fr) |
JP (3) | JP2005518787A (fr) |
KR (1) | KR100870521B1 (fr) |
AU (1) | AU2002366532A1 (fr) |
CA (1) | CA2469792C (fr) |
DE (1) | DE10297513C5 (fr) |
FR (1) | FR2833271B1 (fr) |
GB (1) | GB2399347B (fr) |
WO (1) | WO2003050271A2 (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2005007839A1 (ja) * | 2003-07-22 | 2006-08-31 | 麒麟麦酒株式会社 | ノッチリガンドDelta−1、GM−CSF、TGF−βを用いたヒト末梢血単核球であるCD14陽性細胞からのランゲルハンス細胞の調製方法 |
US20070077237A1 (en) * | 2003-10-09 | 2007-04-05 | Udi Damari | Method for freezing, thawing and transplantation of viable cartilage |
EP1711214A1 (fr) * | 2004-02-02 | 2006-10-18 | Interface Multigrad Technology (IMT) Ltd. | Dispositif de refroidissement directionnel de matiere biologique |
US7935478B2 (en) * | 2004-02-02 | 2011-05-03 | Core Dynamics Limited | Biological material and methods and solutions for preservation thereof |
US7709256B2 (en) | 2004-04-28 | 2010-05-04 | Vaxdesign Corp. | Disease model incorporation into an artificial immune system (AIS) |
US8030070B2 (en) | 2004-04-28 | 2011-10-04 | Sanofi Pasteur Vaxdesign Corp. | Artificial lymphoid tissue equivalent |
US8298824B2 (en) | 2004-04-28 | 2012-10-30 | Sanofi Pasteur Vaxdesign Corporation | Methods of evaluating a test agent in a diseased cell model |
US7771999B2 (en) | 2004-04-28 | 2010-08-10 | Vaxdesign Corp. | Disease model incorporation into an artificial immune system (AIS) |
US7785806B2 (en) | 2004-04-28 | 2010-08-31 | Vaxdesign Corporation | Method for determining the immunogenicity of an antigen |
US7855074B2 (en) | 2004-04-28 | 2010-12-21 | Vaxdesign Corp. | Artificial immune system: methods for making and use |
US8071373B2 (en) | 2004-04-28 | 2011-12-06 | Sanofi Pasteur Vaxdesign Corp. | Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS) |
US7785883B2 (en) | 2004-04-28 | 2010-08-31 | Vax Design Corp. | Automatable artificial immune system (AIS) |
ATE460947T1 (de) * | 2004-06-07 | 2010-04-15 | Core Dynamics Ltd | Verfahren zur sterilisation von biologischen präparaten |
US8037696B2 (en) * | 2004-08-12 | 2011-10-18 | Core Dynamics Limited | Method and apparatus for freezing or thawing of a biological material |
EP1850661A2 (fr) * | 2005-02-22 | 2007-11-07 | Interface Multigrad Technology (IMT) Ltd. | Cartilage viable conserve, son procede de conservation, et systeme et dispositifs de mise en oeuvre |
ES2650569T3 (es) | 2005-04-08 | 2018-01-19 | Argos Therapeutics, Inc. | Composiciones de células dendríticas y métodos |
JP4792566B2 (ja) * | 2005-06-01 | 2011-10-12 | 財団法人ヒューマンサイエンス振興財団 | 樹状細胞を含む三次元培養ヒト皮膚モデル |
US8198085B2 (en) * | 2005-08-03 | 2012-06-12 | Core Dynamics Limited | Somatic cells for use in cell therapy |
US8003387B2 (en) | 2005-12-21 | 2011-08-23 | Sanofi Pasteur Vaxdesign Corp. | In vitro germinal centers |
AU2006330951B2 (en) * | 2005-12-21 | 2012-04-05 | Sanofi Pasteur Vaxdesign Corporation | A porous membrane device that promotes the differentiation of monocytes into dendritic cells |
CA2655344C (fr) | 2006-06-27 | 2016-09-13 | Vaxdesign Corporation | Modeles pour une evaluation de vaccin |
FR2905380B1 (fr) * | 2006-09-04 | 2008-12-05 | Engelhard Lyon Sa | Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ |
DE102007006736B4 (de) * | 2007-02-07 | 2012-01-12 | Dagmar Briechle | In-vitro Testkit zur tierversuchsfreien Bestimmung des sensibilisierenden Potentials einer Substanz |
US8647837B2 (en) | 2007-07-16 | 2014-02-11 | Sanofi Pasteur Vaxdesign Corp. | Artificial tissue constructs comprising alveolar cells and methods for using the same |
US20090202978A1 (en) * | 2008-02-13 | 2009-08-13 | Ginadi Shaham | Method and apparatus for freezing of a biological material |
FR2962443B1 (fr) | 2010-07-06 | 2017-11-17 | Basf Beauty Care Solutions France Sas | Modele de tissu adipeux et procede de preparation |
GB201700138D0 (en) | 2017-01-05 | 2017-02-22 | Senzagen Ab | Analytical methods and arrays for use in the same |
FR3132146A1 (fr) * | 2022-01-27 | 2023-07-28 | Genoskin | Modèle humain ex vivo destiné à l’évaluation du potentiel vaccinal d’une composition |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2743817B1 (fr) * | 1996-01-23 | 1998-03-13 | Oreal | Equivalent de peau comprenant des cellules de langerhans |
FR2759381B1 (fr) * | 1997-02-11 | 1999-04-16 | Oreal | Procede d'evaluation du potentiel sensibilisant et/ou irritant et/ou allergene d'un produit |
DE19839113A1 (de) * | 1998-08-27 | 2000-03-02 | Univ Ludwigs Albert | Verfahren zur Herstellung von dendritischen Zellen mit niedermolekularen Fragmenten der Hyaluronsäure |
-
2001
- 2001-12-10 FR FR0115942A patent/FR2833271B1/fr not_active Expired - Lifetime
-
2002
- 2002-12-10 WO PCT/EP2002/014874 patent/WO2003050271A2/fr active Application Filing
- 2002-12-10 GB GB0412968A patent/GB2399347B/en not_active Expired - Fee Related
- 2002-12-10 JP JP2003551293A patent/JP2005518787A/ja active Pending
- 2002-12-10 DE DE10297513.2T patent/DE10297513C5/de not_active Expired - Fee Related
- 2002-12-10 KR KR1020047008890A patent/KR100870521B1/ko not_active IP Right Cessation
- 2002-12-10 CA CA2469792A patent/CA2469792C/fr not_active Expired - Fee Related
- 2002-12-10 US US10/496,879 patent/US20050008623A1/en not_active Abandoned
- 2002-12-10 AU AU2002366532A patent/AU2002366532A1/en not_active Abandoned
-
2009
- 2009-04-15 JP JP2009098971A patent/JP5209566B2/ja not_active Expired - Fee Related
- 2009-04-15 JP JP2009098970A patent/JP5101559B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP5209566B2 (ja) | 2013-06-12 |
WO2003050271A3 (fr) | 2004-01-15 |
DE10297513T5 (de) | 2005-02-10 |
JP2009159987A (ja) | 2009-07-23 |
GB2399347A (en) | 2004-09-15 |
CA2469792A1 (fr) | 2003-06-19 |
DE10297513B4 (de) | 2007-06-14 |
GB0412968D0 (en) | 2004-07-14 |
AU2002366532A8 (en) | 2003-06-23 |
CA2469792C (fr) | 2014-09-30 |
JP5101559B2 (ja) | 2012-12-19 |
AU2002366532A1 (en) | 2003-06-23 |
FR2833271A1 (fr) | 2003-06-13 |
KR100870521B1 (ko) | 2008-11-26 |
JP2009167206A (ja) | 2009-07-30 |
DE10297513C5 (de) | 2014-09-04 |
WO2003050271A2 (fr) | 2003-06-19 |
JP2005518787A (ja) | 2005-06-30 |
GB2399347B (en) | 2006-05-31 |
US20050008623A1 (en) | 2005-01-13 |
KR20040065241A (ko) | 2004-07-21 |
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