FR2905380B1 - Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ - Google Patents
Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+Info
- Publication number
- FR2905380B1 FR2905380B1 FR0653567A FR0653567A FR2905380B1 FR 2905380 B1 FR2905380 B1 FR 2905380B1 FR 0653567 A FR0653567 A FR 0653567A FR 0653567 A FR0653567 A FR 0653567A FR 2905380 B1 FR2905380 B1 FR 2905380B1
- Authority
- FR
- France
- Prior art keywords
- cells
- dermic
- monocytes
- interstitial
- dentritic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 title 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 210000001821 langerhans cell Anatomy 0.000 title 1
- 210000001616 monocyte Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/097—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells oral mucosa cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1121—Dendritic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1157—Monocytes, macrophages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/24—Genital tract cells, non-germinal cells from gonads
- C12N2502/243—Cells of the female genital tract, non-germinal ovarian cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0653567A FR2905380B1 (fr) | 2006-09-04 | 2006-09-04 | Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ |
JP2009526123A JP2010502175A (ja) | 2006-09-04 | 2007-09-03 | Cd14+単球からランゲルハンス細胞及び/又は真皮/間質性樹状細胞を製造する方法 |
KR1020097006847A KR20090049620A (ko) | 2006-09-04 | 2007-09-03 | Cd14+ 단구로부터 랑게르한스 세포 및/또는 진피/간질성 수지상 세포를 생성시키는 방법 |
PCT/EP2007/059165 WO2008028882A1 (fr) | 2006-09-04 | 2007-09-03 | Procédé de production de cellules de langerhans et/ou des cellules dendritiques dermiques/interstitielles à partir de monocytes cd14+ |
BRPI0716107-7A2A BRPI0716107A2 (pt) | 2006-09-04 | 2007-09-03 | mÉtodos para preparar cÉlulas de langerhans ou cÉlulas dendrÍticas e para diferenciar monàcitos, modelo de cÉlulas, monàcitos cd14+ congelados, uso de pelo menos um modelo de cÉlula e/ou de pelo menos um modelo de tecido, e, mÉtodos para produzir um modelo de tecido, e uma pele reconstruÍda ou uma mucosa reconstruÍda |
EP07803152A EP2064318A1 (fr) | 2006-09-04 | 2007-09-03 | Procédé de production de cellules de langerhans et/ou des cellules dendritiques dermiques/interstitielles à partir de monocytes cd14+ |
CA002662231A CA2662231A1 (fr) | 2006-09-04 | 2007-09-03 | Procede de production de cellules de langerhans et/ou des cellules dendritiques dermiques/interstitielles a partir de monocytes cd14+ |
US12/851,592 US20100297765A1 (en) | 2006-09-04 | 2010-08-06 | Method for producing langerhans cells or interstitial dendritic cells or both from cd14+ monocytes |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0653567A FR2905380B1 (fr) | 2006-09-04 | 2006-09-04 | Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2905380A1 FR2905380A1 (fr) | 2008-03-07 |
FR2905380B1 true FR2905380B1 (fr) | 2008-12-05 |
Family
ID=37781699
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0653567A Expired - Fee Related FR2905380B1 (fr) | 2006-09-04 | 2006-09-04 | Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2064318A1 (fr) |
JP (1) | JP2010502175A (fr) |
KR (1) | KR20090049620A (fr) |
BR (1) | BRPI0716107A2 (fr) |
CA (1) | CA2662231A1 (fr) |
FR (1) | FR2905380B1 (fr) |
WO (1) | WO2008028882A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120171194A1 (en) * | 2009-03-17 | 2012-07-05 | Colin Tso | Method of Cell Differentiation and Uses Therefor in Screening, Diagnosis and Therapy |
GB201700138D0 (en) | 2017-01-05 | 2017-02-22 | Senzagen Ab | Analytical methods and arrays for use in the same |
JP7522042B2 (ja) * | 2018-11-30 | 2024-07-24 | 株式会社 資生堂 | 色素沈着皮膚モデルおよびその製造方法、ならびに皮膚の色素沈着を治療または予防するための因子の評価方法 |
CN114258428A (zh) * | 2019-09-17 | 2022-03-29 | 凸版印刷株式会社 | 细胞结构体及其制造方法 |
FR3132146A1 (fr) * | 2022-01-27 | 2023-07-28 | Genoskin | Modèle humain ex vivo destiné à l’évaluation du potentiel vaccinal d’une composition |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2743817B1 (fr) * | 1996-01-23 | 1998-03-13 | Oreal | Equivalent de peau comprenant des cellules de langerhans |
US7566568B2 (en) * | 2001-04-27 | 2009-07-28 | Istituto Superiore Di Sanita | Method for generating highly active human dendritic cells from peripheral blood mononuclear cells |
FR2833271B1 (fr) * | 2001-12-10 | 2004-09-17 | Coletica | Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles |
EP1688483A4 (fr) * | 2003-07-22 | 2007-09-12 | Kirin Brewery | Procede de preparation de cellules de langerhans a partir de cellules positives cd14 qui sont des cellules mononucleaires du sang humain a l'aide d'un ligand notch delta-1, gm-csf et tgf-beta |
-
2006
- 2006-09-04 FR FR0653567A patent/FR2905380B1/fr not_active Expired - Fee Related
-
2007
- 2007-09-03 BR BRPI0716107-7A2A patent/BRPI0716107A2/pt not_active IP Right Cessation
- 2007-09-03 KR KR1020097006847A patent/KR20090049620A/ko not_active Application Discontinuation
- 2007-09-03 JP JP2009526123A patent/JP2010502175A/ja active Pending
- 2007-09-03 EP EP07803152A patent/EP2064318A1/fr not_active Withdrawn
- 2007-09-03 WO PCT/EP2007/059165 patent/WO2008028882A1/fr active Application Filing
- 2007-09-03 CA CA002662231A patent/CA2662231A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI0716107A2 (pt) | 2013-09-24 |
KR20090049620A (ko) | 2009-05-18 |
FR2905380A1 (fr) | 2008-03-07 |
EP2064318A1 (fr) | 2009-06-03 |
JP2010502175A (ja) | 2010-01-28 |
WO2008028882A1 (fr) | 2008-03-13 |
CA2662231A1 (fr) | 2008-03-13 |
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FR2905380B1 (fr) | Procede de production de cellules de langerhans et/ou de cellules de dentritiques interstitielles/dermiques a partir de monocytes cd14+ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 11 |
|
ST | Notification of lapse |
Effective date: 20180531 |