ATE542123T1 - Verbessertes verfahren zum einfrieren lebensfähiger zellen - Google Patents

Verbessertes verfahren zum einfrieren lebensfähiger zellen

Info

Publication number
ATE542123T1
ATE542123T1 AT02772760T AT02772760T ATE542123T1 AT E542123 T1 ATE542123 T1 AT E542123T1 AT 02772760 T AT02772760 T AT 02772760T AT 02772760 T AT02772760 T AT 02772760T AT E542123 T1 ATE542123 T1 AT E542123T1
Authority
AT
Austria
Prior art keywords
freezing
improved method
viable cells
sample
biological
Prior art date
Application number
AT02772760T
Other languages
English (en)
Inventor
Yehudit Natan
Meir Uri
Yoram Amsalem
Original Assignee
Core Dynamics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Core Dynamics Ltd filed Critical Core Dynamics Ltd
Priority claimed from PCT/IL2002/000738 external-priority patent/WO2003020874A2/en
Application granted granted Critical
Publication of ATE542123T1 publication Critical patent/ATE542123T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
    • A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0278—Physical preservation processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1894—Cooling means; Cryo cooling
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/809—Incubators or racks or holders for culture plates or containers

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Combustion & Propulsion (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT02772760T 2002-06-27 2002-09-05 Verbessertes verfahren zum einfrieren lebensfähiger zellen ATE542123T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39157502P 2002-06-27 2002-06-27
PCT/IL2002/000738 WO2003020874A2 (en) 2001-09-06 2002-09-05 Improved method for freezing viable cells

Publications (1)

Publication Number Publication Date
ATE542123T1 true ATE542123T1 (de) 2012-02-15

Family

ID=45561220

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02772760T ATE542123T1 (de) 2002-06-27 2002-09-05 Verbessertes verfahren zum einfrieren lebensfähiger zellen

Country Status (2)

Country Link
US (1) US7659111B2 (de)
AT (1) ATE542123T1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE494777T1 (de) * 2003-10-09 2011-01-15 Core Dynamics Ltd Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel
EP1711053A2 (de) * 2004-02-02 2006-10-18 I.M.T. Interface Multigrad Technology Ltd. Biologisches material sowie verfahren und lösungen für seine konservierung
WO2005072790A1 (en) * 2004-02-02 2005-08-11 I.M.T. Interface Multigrad Technology Ltd. Device for directional cooling of biological matter
EP1753472B1 (de) * 2004-06-07 2010-03-17 Core Dynamics Ltd Verfahren zur sterilisation von biologischen präparaten
FI116946B (fi) * 2004-07-09 2006-04-13 Chip Man Technologies Oy Laitteisto solujen kuvaamiseksi
WO2006016372A1 (en) * 2004-08-12 2006-02-16 I.M.T. Interface Multigrad Technology Ltd. Method and apparatus for freezing or thawing of a biological material
US20080160496A1 (en) * 2005-02-22 2008-07-03 Victor Rzepakovsky Preserved Viable Cartilage, Method for Its Preservation, and System and Devices Used Therefor
EP1909565A2 (de) 2005-08-03 2008-04-16 Interface Multigrad Technology (IMT) Ltd. Somatische zellen für die zelltherapie
FR2891166B1 (fr) * 2005-09-28 2007-11-23 Cryo Bio System Sa Enveloppe de conditionnement d'un volume predetermine de substance biologique destinee a etre plongee dans un agent cryogenique liquide
FR2891165B1 (fr) * 2005-09-28 2008-01-11 Cryo Bio System Sa Ensemble de conditionnement d'un volume predetermine de substance a conserver par vitrification cryogenique.
WO2008024575A2 (en) * 2006-07-21 2008-02-28 The Curators Of The University Of Missouri A cryopreservation device and method
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
EP2521444A2 (de) 2010-01-07 2012-11-14 Core Dynamics Ltd Verfahren zum präsevieren von knochenspongiosaproben und präserviertes knochenspongiosagewebe
EP2686419B1 (de) 2011-03-18 2016-11-16 MicroVascular Tissues, Inc. Allogenes mikrovaskuläres gewebe für weichgewebebehandlungen
US10596202B2 (en) 2012-09-19 2020-03-24 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9872937B2 (en) 2012-09-19 2018-01-23 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9713629B2 (en) 2012-09-19 2017-07-25 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US11819522B2 (en) 2012-09-19 2023-11-21 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
WO2019178121A1 (en) * 2018-03-12 2019-09-19 The Penn State Research Foundation Method and apparatus for temperature gradient microfluidics
US12070044B2 (en) 2019-02-22 2024-08-27 Aquero Canada Ltd. Fortified milk compositions and their processes of preparation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3347745A (en) * 1963-12-06 1967-10-17 Union Carbide Corp Process for freezing erythrocytes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US5071598A (en) * 1987-12-03 1991-12-10 California Institute Of Technology Cryoprotective reagent
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
US5059518A (en) * 1988-10-20 1991-10-22 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
AU650045B2 (en) * 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
RU1806692C (ru) 1990-12-19 1993-04-07 Украинский Научно-Исследовательский Институт По Племенному Делу В Животноводстве Способ криоконсервации спермы сельскохоз йственных животных и установка дл его осуществлени
US5873254A (en) * 1996-09-06 1999-02-23 Interface Multigrad Technology Device and methods for multigradient directional cooling and warming of biological samples
US6073540A (en) * 1998-11-10 2000-06-13 Fmc Corporation Apparatus for heating or cooling product containers
JP2000189155A (ja) 1998-12-25 2000-07-11 Livestock Improvement Association Of Japan Inc 哺乳動物胚または卵子の保存方法並びに凍結胚または卵子の融解希釈方法

Also Published As

Publication number Publication date
US7659111B2 (en) 2010-02-09
US20040191754A1 (en) 2004-09-30

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