JP3569916B2 - 腫瘍の治療のための製薬学的製品とそれの製造方法 - Google Patents

腫瘍の治療のための製薬学的製品とそれの製造方法

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Publication number
JP3569916B2
JP3569916B2 JP50829793A JP50829793A JP3569916B2 JP 3569916 B2 JP3569916 B2 JP 3569916B2 JP 50829793 A JP50829793 A JP 50829793A JP 50829793 A JP50829793 A JP 50829793A JP 3569916 B2 JP3569916 B2 JP 3569916B2
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Japan
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ppm
water
deuterium
deuterium content
product
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP50829793A
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English (en)
Japanese (ja)
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JPH08501275A (ja
Inventor
ソミャイ，ガーボル
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Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP50829793A 1991-10-31 1992-09-28 腫瘍の治療のための製薬学的製品とそれの製造方法 Expired - Lifetime JP3569916B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU913437A HU208084B (en) 1991-10-31 1991-10-31 Process for producing compositions suitable for curing tumorous diseases
HU3437/91 1991-10-31
PCT/HU1992/000036 WO1993008794A1 (en) 1991-10-31 1992-09-28 Pharmaceutical products for curing tumorous diseases and process for preparing same

Publications (2)

Publication Number Publication Date
JPH08501275A JPH08501275A (ja) 1996-02-13
JP3569916B2 true JP3569916B2 (ja) 2004-09-29

Family

ID=10964023

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50829793A Expired - Lifetime JP3569916B2 (ja) 1991-10-31 1992-09-28 腫瘍の治療のための製薬学的製品とそれの製造方法

Country Status (22)

Country Link
US (1) US5855921A (OSRAM)
JP (1) JP3569916B2 (OSRAM)
KR (1) KR100253874B1 (OSRAM)
CN (1) CN1045162C (OSRAM)
AT (1) AT402692B (OSRAM)
BE (1) BE1006186A3 (OSRAM)
CA (1) CA2122612C (OSRAM)
CH (1) CH685282A5 (OSRAM)
CZ (1) CZ282379B6 (OSRAM)
DE (1) DE4232465B4 (OSRAM)
DK (1) DK170832B1 (OSRAM)
ES (1) ES2077530B1 (OSRAM)
FI (1) FI114010B (OSRAM)
FR (1) FR2683148B1 (OSRAM)
GB (1) GB2276086B (OSRAM)
HU (1) HU208084B (OSRAM)
IT (1) IT1255390B (OSRAM)
LU (1) LU88175A1 (OSRAM)
NL (1) NL194664C (OSRAM)
NO (1) NO307031B1 (OSRAM)
SE (1) SE513624C2 (OSRAM)
WO (1) WO1993008794A1 (OSRAM)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT738114E (pt) * 1994-01-06 2002-02-28 Hyd Kutato Fejleszto Ktf Produtos alimentares para a prevencao do desenvolvimento de doencas e processos para a sua preparacao
HU214593B (hu) * 1994-03-23 1998-06-29 HYD Kutató-Fejlesztő Kft. Kozmetikai, higiéniai, valamint szépség- és testápoló készítmények és eljárás azok előállítására
DE4427690A1 (de) * 1994-08-04 1996-02-08 Bogdahn Ulrich Prof Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum
HU217418B (hu) * 1995-04-20 2000-01-28 László Kótai Kémiai eljárás alacsony deutériumtartalmú víz előállítására
RU2083210C1 (ru) * 1995-09-13 1997-07-10 Николаева Ирина Сергеевна Средство для профилактической, поддерживающей и восстановительной терапии развивающихся при старении и/или под воздействием патогенных факторов патологий, связанных с дистрофическим и дегенеративными изменениями органов и тканей
US6444238B1 (en) 2000-03-10 2002-09-03 General Cosmetics Corporation Pain relief composition and method of relieving pain
HU226984B1 (en) * 2001-12-12 2010-04-28 Hyd Kutato Fejlesztoe Kft Medical and food products for treating diabetes mellitus and process for producing thereof
EP1483399B1 (en) * 2002-02-12 2008-10-29 The Regents of the University of California Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products
AU2003256819B2 (en) 2002-07-30 2009-11-12 The Regents Of The University Of California Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry
WO2004022098A1 (en) * 2002-09-09 2004-03-18 Borsos Ferenc Oxygen-enriched water, treated within a magnetic field and heavy water
ATE415486T1 (de) * 2002-09-13 2008-12-15 Univ California Verfahren zur messung der geschwindigkeiten des cholesterinrückwärtstransports in vivo als index für anti-artherogenese
WO2004042360A2 (en) 2002-11-04 2004-05-21 The Regents Of The Univeristy Of California Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body
JP2004315487A (ja) * 2003-04-17 2004-11-11 Internatl Scient:Kk 重水素減少水（スーパーライトウォーター）を原料とするスポーツドリンクの飲用による筋肉増強、及び製造方法。
RO120171B1 (ro) * 2003-05-23 2005-10-28 Ioan Nedelcu Produse cosmetice şi pentru igienă, procedeu de obţinere şi procedeu de aplicare a acestora
US7262020B2 (en) * 2003-07-03 2007-08-28 The Regents Of The University Of California Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol
RO120505B1 (ro) * 2003-08-13 2006-02-28 Institutul Oncologic Profesor Dr. Al. Trestioreanu Metodă pentru stabilirea in vivo la animale de experienţă, a concentraţiei eficiente de apă sărăcită în deuteriu pentru tratamentul cancerului
US20050202406A1 (en) * 2003-11-25 2005-09-15 The Regents Of The University Of California Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
WO2005070438A1 (en) * 2004-01-23 2005-08-04 Igor Anatolievich Pomytkin Pharmaceutical composition comprising water depleted of heavy isotopes 0-17 and 0-18
TW200538738A (en) 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
US20050226825A1 (en) * 2004-04-13 2005-10-13 Giampapa Vincent C Topical composition for preventing and treating skin damage caused by UV light exposure
WO2005117566A1 (ja) * 2004-06-03 2005-12-15 Kunihiro Seki 低重水素濃度食品の生産装置
RO121676B1 (ro) * 2004-08-18 2008-02-28 Institutul Oncologic "Prof.Dr. Al. Trestioreanu" Metodă de creştere a toleranţei organismului la tratamentul cu citostatice
RS20070330A (sr) * 2005-02-08 2009-03-25 Woodford Asociates Ltd., Alkoholno piće obogaćeno sa 1h216o
AU2005327332B2 (en) 2005-02-08 2010-07-22 Woodford Associates Limited Non-alcoholic beverage enriched with 1H216O
KR100928384B1 (ko) * 2005-03-05 2009-11-23 세르게이 파브로비치 솔로비에프 1h216o가 강화된 화장품 조성물
EP1855699B1 (en) * 2005-03-11 2012-08-15 Sergey Pavlovich Soloviev Light pharmaceutical water and therapeutic compositions and methods thereof
EA012187B1 (ru) * 2005-03-11 2009-08-28 Вада Консалтинг Лимитед Способы для интрадермальной, трансдермальной или трансмукозальной доставки биологически активных веществ
EA012822B1 (ru) * 2005-03-11 2009-12-30 Вада Консалтинг Лимитед Композиции для дезинфекции поверхностей неодушевленных предметов
RU2275920C1 (ru) * 2005-04-01 2006-05-10 Игорь Анатольевич Помыткин Способ лечения новообразований
RU2287324C1 (ru) * 2005-04-29 2006-11-20 Тамази Владимирович Баззаев Мазь для лечения ожоговых ран
US20060251576A1 (en) * 2005-05-03 2006-11-09 The Regents Of The University Of California Methods for measuring cholesterol metabolism and transport
TW200711660A (en) * 2005-06-10 2007-04-01 Univ California Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
WO2007069933A1 (en) * 2005-12-12 2007-06-21 Vada Consulting Limited Method for decreasing postprandial glucose excursion
US20080292719A1 (en) * 2005-12-12 2008-11-27 Igor Anatolievich Pomytkin Method of Treating Metabolic Syndrome
WO2007069932A1 (en) * 2005-12-12 2007-06-21 Vada Consulting Limited Method for suppressing appetite and food intake
HUP0900231A2 (hu) * 2009-04-16 2010-11-29 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Allergiás betegségek kezelésére, gyógyítására alkalmas készítmények és eljárás azok elõállítására
DE202009018629U1 (de) 2009-04-21 2012-06-11 Renate Rohlf Gesundheitsförderndes flüssiges Nahrungsmittel
US8658236B2 (en) * 2009-08-21 2014-02-25 Deuteria Beverages, Llc Alcoholic compositions having a lowered risk of acetaldehydemia
WO2012166459A1 (en) * 2011-05-27 2012-12-06 Bristol-Myers Squibb Company Tripeptides incorporating deuterium as inhibitors of hepatitis c virus
HUP1100290A2 (en) 2011-06-01 2012-12-28 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Combination compositions for the treatment of proliferative diseases
WO2013036885A1 (en) 2011-09-08 2013-03-14 The Regents Of The University Of California Metabolic flux measurement, imaging and microscopy
US20140353486A1 (en) 2011-12-07 2014-12-04 Glaxosmithkline Llc Methods for determining total body skeletal muscle mass
HUP1200552A2 (en) 2012-09-21 2014-04-28 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Pharmaceutical compositions for the treatment of high blood pressure
WO2014088441A1 (en) * 2012-12-03 2014-06-12 Igor Anatolievich Pomytkin Food for the dietary management of burnout
US9134319B2 (en) 2013-03-15 2015-09-15 The Regents Of The University Of California Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
CN103462830A (zh) * 2013-09-03 2013-12-25 大连世纪新源技术开发有限公司 超轻水多肽化妆品及其制备方法
US20150374745A1 (en) * 2014-06-30 2015-12-31 Mitochondrial Substrate Invention Limited Nutrients solutions for enhancement of cognitive function
RU2601046C1 (ru) * 2015-07-29 2016-10-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кубанский государственный университет" (ФГБОУ ВПО "КубГУ") Способ снижения содержания дейтерия в пищевых сельскохозяйственных культурах
WO2018053578A1 (en) * 2016-09-21 2018-03-29 Ambrosios Kambouris Isotopic compositions
AU2018400230B2 (en) * 2018-01-02 2024-06-13 Botanical Water Technologies Ip Ltd Isotopic compositions II
WO2019174659A1 (de) 2018-03-15 2019-09-19 Karl Bau Gmbh Verfahren und anordnung zur herstellung von deuterium reduziertem wasser
CN112811559A (zh) * 2020-12-30 2021-05-18 江苏奥特泉超轻水饮料有限公司 一种低氘氢水及其制备方法及应用
CN120078803A (zh) * 2025-03-05 2025-06-03 江苏睿景生物技术有限公司 低氘水对肿瘤细胞生长抑制的作用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3807960A (en) * 1969-08-04 1974-04-30 V Thayer Apparatus for enrichment of deuterium between water and hydrogen sulfide by countercurrent mass transfer
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
JPS56141822A (en) * 1980-04-07 1981-11-05 Hitachi Ltd Method for separating and recovering hydrogen isomer
US4411798A (en) * 1980-05-27 1983-10-25 Standard Oil Company Process for separating D2 O from H2 O using surfactant systems
FR2552324B1 (fr) * 1983-09-23 1985-11-22 Ionescu Pantelimon Dumitru Eau anticancereuse, procede pour sa realisation, outillage pour sa conservation, et methode pour le traitement du cancer
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
DE3717883A1 (de) * 1987-05-27 1988-12-15 Schiwa Gmbh Verfahren und anordnung zur herstellung von physiologischen loesungen
AU1966188A (en) * 1987-08-07 1989-03-09 Mallinckrodt, Inc. Diagnostic or radiotherapeutic composition comprising a hydrogen containing compound
IL85312A (en) * 1988-02-03 1991-08-16 Israel State Injectable pharmaceutical compositions having improved stability
US4931154A (en) * 1989-07-17 1990-06-05 Southwestern Analytical Chemicals, Inc. Production of metal borohydrides and organic onium borohydrides
US5223269A (en) * 1989-08-31 1993-06-29 Andrejs Liepins Methods and composition for the treatment of hypertension

Also Published As

Publication number Publication date
SE9401406L (sv) 1994-06-07
ATA902992A (de) 1996-12-15
ES2077530B1 (es) 1996-07-01
US5855921A (en) 1999-01-05
AT402692B (de) 1997-07-25
NO307031B1 (no) 2000-01-31
GB2276086B (en) 1995-09-27
IT1255390B (it) 1995-10-31
FI941979A0 (fi) 1994-04-29
KR100253874B1 (ko) 2000-04-15
HU913437D0 (en) 1992-01-28
NL9220026A (nl) 1994-09-01
BE1006186A3 (fr) 1994-06-07
GB9408654D0 (en) 1994-07-20
CN1045162C (zh) 1999-09-22
ES2077530A1 (es) 1995-11-16
FI941979L (fi) 1994-06-29
ITMI922233A0 (it) 1992-09-28
FI114010B (fi) 2004-07-30
HU208084B (en) 1993-08-30
CN1071836A (zh) 1993-05-12
GB2276086A (en) 1994-09-21
DE4232465B4 (de) 2008-11-06
LU88175A1 (fr) 1993-03-15
FR2683148A1 (fr) 1993-05-07
ITMI922233A1 (it) 1994-03-28
CZ102094A3 (en) 1994-12-15
NO941590L (OSRAM) 1994-06-23
SE513624C2 (sv) 2000-10-09
SE9401406D0 (sv) 1994-04-25
NO941590D0 (OSRAM) 1994-04-29
CZ282379B6 (cs) 1997-07-16
NL194664B (nl) 2002-07-01
KR930007461A (ko) 1993-05-20
JPH08501275A (ja) 1996-02-13
DE4232465A1 (de) 1993-05-06
FR2683148B1 (fr) 1994-09-09
NL194664C (nl) 2002-11-04
DK170832B1 (da) 1996-02-05
CA2122612C (en) 2003-02-04
WO1993008794A1 (en) 1993-05-13
CH685282A5 (de) 1995-05-31
CA2122612A1 (en) 1993-05-13

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