JP2564386B2 - 水不溶性ポリマーの粉末の調整方法 - Google Patents

水不溶性ポリマーの粉末の調整方法

Info

Publication number
JP2564386B2
JP2564386B2 JP63503317A JP50331788A JP2564386B2 JP 2564386 B2 JP2564386 B2 JP 2564386B2 JP 63503317 A JP63503317 A JP 63503317A JP 50331788 A JP50331788 A JP 50331788A JP 2564386 B2 JP2564386 B2 JP 2564386B2
Authority
JP
Japan
Prior art keywords
water
polymer
solution
solute
organic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63503317A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01502991A (ja
Inventor
クリスチャン ビンチャエドラー
ロベール グルニィ
エリック ドルカー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH01502991A publication Critical patent/JPH01502991A/ja
Application granted granted Critical
Publication of JP2564386B2 publication Critical patent/JP2564386B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/07—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from polymer solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
JP63503317A 1987-04-16 1988-04-01 水不溶性ポリマーの粉末の調整方法 Expired - Lifetime JP2564386B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1497/87-6 1987-04-16
CH149787 1987-04-16
CA000580702A CA1340020C (en) 1987-04-16 1988-10-20 Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof

Publications (2)

Publication Number Publication Date
JPH01502991A JPH01502991A (ja) 1989-10-12
JP2564386B2 true JP2564386B2 (ja) 1996-12-18

Family

ID=25672190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63503317A Expired - Lifetime JP2564386B2 (ja) 1987-04-16 1988-04-01 水不溶性ポリマーの粉末の調整方法

Country Status (15)

Country Link
US (1) US4968350A (enExample)
EP (2) EP0309527B1 (enExample)
JP (1) JP2564386B2 (enExample)
AT (1) ATE84806T1 (enExample)
AU (1) AU610594B2 (enExample)
BR (1) BR8806902A (enExample)
CA (1) CA1340020C (enExample)
DE (1) DE3877678T2 (enExample)
DK (1) DK173005B1 (enExample)
ES (1) ES2035949T3 (enExample)
FI (1) FI96219C (enExample)
GR (1) GR3006969T3 (enExample)
IE (1) IE62111B1 (enExample)
NO (1) NO174208C (enExample)
WO (1) WO1988008011A1 (enExample)

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US5326572A (en) * 1989-03-23 1994-07-05 Fmc Corporation Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions
US5258436A (en) * 1989-12-19 1993-11-02 Fmc Corporation Film-forming composition; method of producing same and use for coating pharmaceuticals and foods and the like
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DE69435137D1 (de) * 1993-05-13 2008-10-16 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
JP2812164B2 (ja) * 1993-11-30 1998-10-22 三菱化学株式会社 カルボン酸基含有重合体粉末の製造方法
JP3492787B2 (ja) * 1994-04-15 2004-02-03 信越化学工業株式会社 固形製剤のコーティング用水性エマルジョンの濃縮方法
US20040018236A1 (en) * 1995-05-08 2004-01-29 Robert Gurny Nanoparticles for oral administration of pharmaceutical agents of low solubility
CA2223595C (en) 1995-06-07 2008-08-05 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
DK0752245T3 (da) * 1995-07-05 2002-09-09 Europ Economic Community Biokompatible og bionedbrydelige nanopartikler udviklet til absorption og afgivelse af proteinholdige lægemidler
FR2740461B1 (fr) * 1995-10-25 1997-12-19 Rhone Poulenc Chimie Composition pulverulente redispersable dans l'eau de polymeres filmogenes prepares a partir de monomeres a insaturation ethylenique
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6413489B1 (en) 1997-04-15 2002-07-02 Massachusetts Institute Of Technology Synthesis of nanometer-sized particles by reverse micelle mediated techniques
US6153231A (en) * 1997-06-25 2000-11-28 Wm. Wrigley Jr. Company Environmentally friendly chewing gum bases
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
DE19737481A1 (de) 1997-08-28 1999-03-04 Hoechst Ag Sphärische lineare Polysaccharide enthaltende Mikropartikel
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
US5985313A (en) * 1997-10-22 1999-11-16 New York Blood Center, Inc. Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
FR2774383B1 (fr) * 1998-02-02 2001-06-01 Rhodia Chimie Sa Composition pulverulente redispersable dans l'eau a base de polymere filmogene et d'au moins un polypeptide
DE19839212C2 (de) * 1998-08-28 2002-05-23 Celanese Ventures Gmbh Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen
DE19839214C1 (de) * 1998-08-28 2000-05-25 Aventis Res & Tech Gmbh & Co Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
CA2400172C (en) 2000-02-28 2010-04-20 Genesegues, Inc. Nanocapsule encapsulation system and method
WO2001080835A1 (fr) * 2000-04-24 2001-11-01 Tanabe Seiyaku Co., Ltd. Procede de production de microspheres
US6316592B1 (en) 2000-05-04 2001-11-13 General Electric Company Method for isolating polymer resin from solution slurries
SE0003125D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Modified polymers
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
US7455858B2 (en) 2002-05-16 2008-11-25 Qlt Inc. Compositions and methods for delivery of photosensitive drugs
DE102005025057B4 (de) 2005-05-30 2008-01-10 Gkss-Forschungszentrum Geesthacht Gmbh Verfahren zum Herstellen von Nanopartikeln unter Verwendung poröser Membranen
US7674608B2 (en) 2007-02-23 2010-03-09 The University Of Toledo Saccharifying cellulose
JP5563313B2 (ja) 2007-03-14 2014-07-30 ザ・ユニバーシティ・オブ・トレド バイオマス前処理
US7999355B2 (en) * 2008-07-11 2011-08-16 Air Products And Chemicals, Inc. Aminosilanes for shallow trench isolation films
EP2623542B1 (en) * 2010-09-28 2017-05-24 Toray Industries, Inc. Polymer microparticles and process for production thereof
EP3188716B1 (en) 2014-09-03 2022-10-26 GeneSegues, Inc. Therapeutic nanoparticles and related compositions, methods and systems
ES2906324T3 (es) 2016-02-29 2022-04-18 Michelman Inc Dispersión hidrolíticamente estable de base acuosa de un polímero biodegradable
CA3087881A1 (en) 2017-01-17 2018-07-26 Michael David FORREST Therapeutic inhibitors of the reverse mode of atp synthase
US12337000B2 (en) 2017-07-13 2025-06-24 Michael David FORREST Therapeutic modulators of the reverse mode of ATP synthase
BR112022000453A2 (pt) * 2019-07-10 2022-03-03 Dainichiseika Color Chem Método para fabricação de grânulos de resina, grânulos de resina e produto que emprega grânulos de resina
JP6779400B1 (ja) 2020-03-04 2020-11-04 大日精化工業株式会社 樹脂ビーズ、樹脂ビーズの製造方法、及び樹脂ビーズを用いた製品
JP6872068B1 (ja) 2020-09-01 2021-05-19 大日精化工業株式会社 樹脂ビーズ、樹脂ビーズの製造方法、及び樹脂ビーズを用いた製品
JP6921293B1 (ja) 2020-12-23 2021-08-18 大日精化工業株式会社 樹脂ビーズ、樹脂ビーズの製造方法、及び樹脂ビーズを用いた製品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2809120A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Cellulose ester compositions
US2809192A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Method of making cellulose esters in the form of small, dense, spherical particles
FR1264953A (fr) * 1960-08-11 1961-06-23 Basf Ag Procédé pour la production de matières plastiques sous forme de perles
US3485651A (en) * 1967-12-18 1969-12-23 Hercules Inc Water-soluble cellulose ether or starch compositions
US4462839A (en) * 1983-06-16 1984-07-31 Fmc Corporation Enteric coating for pharmaceutical dosage forms
DE3344242A1 (de) * 1983-12-07 1985-06-20 Wacker-Chemie GmbH, 8000 München Verfahren zur herstellung eines redispergierbaren dispersionspulvers und seine anwendung
CA1235119A (en) * 1984-01-24 1988-04-12 Kazuhiro Yamazaki Porous spherical cellulose acetate particles

Also Published As

Publication number Publication date
BR8806902A (pt) 1989-10-31
FI885767L (fi) 1988-12-13
ES2035949T3 (es) 1993-05-01
JPH01502991A (ja) 1989-10-12
AU1680688A (en) 1988-11-04
NO174208B (no) 1993-12-20
IE881026L (en) 1988-10-16
US4968350A (en) 1990-11-06
WO1988008011A1 (en) 1988-10-20
FI96219C (fi) 1996-05-27
DK698688A (da) 1988-12-15
DE3877678T2 (de) 1993-10-07
DK698688D0 (da) 1988-12-15
FI885767A0 (fi) 1988-12-13
EP0363549B1 (en) 1992-12-09
GR3006969T3 (enExample) 1993-06-30
AU610594B2 (en) 1991-05-23
IE62111B1 (en) 1994-12-14
EP0309527A1 (en) 1989-04-05
EP0363549A1 (en) 1990-04-18
NO885570D0 (no) 1988-12-15
NO174208C (no) 1994-03-30
DE3877678D1 (de) 1993-03-04
FI96219B (fi) 1996-02-15
ATE84806T1 (de) 1993-02-15
CA1340020C (en) 1998-09-01
NO885570L (no) 1989-02-14
EP0309527B1 (en) 1993-01-20
DK173005B1 (da) 1999-11-01

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