DE3877678T2 - Verfahren zur herstellung eines wasserunlöslichen polymerpulvers, das in einer flüssigen phase redispergiert werden kann und verfahren zur herstellung einer dispersion des polymerpulvers. - Google Patents

Verfahren zur herstellung eines wasserunlöslichen polymerpulvers, das in einer flüssigen phase redispergiert werden kann und verfahren zur herstellung einer dispersion des polymerpulvers.

Info

Publication number
DE3877678T2
DE3877678T2 DE88903232T DE3877678T DE3877678T2 DE 3877678 T2 DE3877678 T2 DE 3877678T2 DE 88903232 T DE88903232 T DE 88903232T DE 3877678 T DE3877678 T DE 3877678T DE 3877678 T2 DE3877678 T2 DE 3877678T2
Authority
DE
Germany
Prior art keywords
producing
polymer powder
water
liquid phase
redisperged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88903232T
Other languages
English (en)
Other versions
DE3877678D1 (de
Inventor
Christian Bindschaedler
Robert Gurny
Eric Doelker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE3877678D1 publication Critical patent/DE3877678D1/de
Application granted granted Critical
Publication of DE3877678T2 publication Critical patent/DE3877678T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/07—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from polymer solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
DE88903232T 1987-04-16 1988-04-01 Verfahren zur herstellung eines wasserunlöslichen polymerpulvers, das in einer flüssigen phase redispergiert werden kann und verfahren zur herstellung einer dispersion des polymerpulvers. Expired - Fee Related DE3877678T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH149787 1987-04-16
CA000580702A CA1340020C (en) 1987-04-16 1988-10-20 Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof

Publications (2)

Publication Number Publication Date
DE3877678D1 DE3877678D1 (de) 1993-03-04
DE3877678T2 true DE3877678T2 (de) 1993-10-07

Family

ID=25672190

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88903232T Expired - Fee Related DE3877678T2 (de) 1987-04-16 1988-04-01 Verfahren zur herstellung eines wasserunlöslichen polymerpulvers, das in einer flüssigen phase redispergiert werden kann und verfahren zur herstellung einer dispersion des polymerpulvers.

Country Status (15)

Country Link
US (1) US4968350A (de)
EP (2) EP0309527B1 (de)
JP (1) JP2564386B2 (de)
AT (1) ATE84806T1 (de)
AU (1) AU610594B2 (de)
BR (1) BR8806902A (de)
CA (1) CA1340020C (de)
DE (1) DE3877678T2 (de)
DK (1) DK173005B1 (de)
ES (1) ES2035949T3 (de)
FI (1) FI96219C (de)
GR (1) GR3006969T3 (de)
IE (1) IE62111B1 (de)
NO (1) NO174208C (de)
WO (1) WO1988008011A1 (de)

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US5326572A (en) * 1989-03-23 1994-07-05 Fmc Corporation Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions
US5258436A (en) * 1989-12-19 1993-11-02 Fmc Corporation Film-forming composition; method of producing same and use for coating pharmaceuticals and foods and the like
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) * 1993-05-13 1994-11-24 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
JP2812164B2 (ja) * 1993-11-30 1998-10-22 三菱化学株式会社 カルボン酸基含有重合体粉末の製造方法
JP3492787B2 (ja) * 1994-04-15 2004-02-03 信越化学工業株式会社 固形製剤のコーティング用水性エマルジョンの濃縮方法
US20040018236A1 (en) * 1995-05-08 2004-01-29 Robert Gurny Nanoparticles for oral administration of pharmaceutical agents of low solubility
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
PT752245E (pt) * 1995-07-05 2002-09-30 Europ Economic Community Nanoparticulas biocompativeis e biodegradaveis destinadas a absorcao e administracao de farmacos proteinaceos
FR2740461B1 (fr) * 1995-10-25 1997-12-19 Rhone Poulenc Chimie Composition pulverulente redispersable dans l'eau de polymeres filmogenes prepares a partir de monomeres a insaturation ethylenique
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6413489B1 (en) * 1997-04-15 2002-07-02 Massachusetts Institute Of Technology Synthesis of nanometer-sized particles by reverse micelle mediated techniques
US6153231A (en) * 1997-06-25 2000-11-28 Wm. Wrigley Jr. Company Environmentally friendly chewing gum bases
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
DE19737481A1 (de) * 1997-08-28 1999-03-04 Hoechst Ag Sphärische lineare Polysaccharide enthaltende Mikropartikel
US5985313A (en) * 1997-10-22 1999-11-16 New York Blood Center, Inc. Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
FR2774383B1 (fr) * 1998-02-02 2001-06-01 Rhodia Chimie Sa Composition pulverulente redispersable dans l'eau a base de polymere filmogene et d'au moins un polypeptide
DE19839214C1 (de) * 1998-08-28 2000-05-25 Aventis Res & Tech Gmbh & Co Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
DE19839212C2 (de) * 1998-08-28 2002-05-23 Celanese Ventures Gmbh Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen
EP1267946A4 (de) 2000-02-28 2008-07-02 Genesegues Inc Nanokapsel-einkapselungs-system und verfahren
EP1277465A1 (de) * 2000-04-24 2003-01-22 Tanabe Seiyaku Co., Ltd. Prozess zur herstellung von mikrosphären
US6316592B1 (en) * 2000-05-04 2001-11-13 General Electric Company Method for isolating polymer resin from solution slurries
SE0003125D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Modified polymers
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
US7455858B2 (en) 2002-05-16 2008-11-25 Qlt Inc. Compositions and methods for delivery of photosensitive drugs
DE102005025057B4 (de) 2005-05-30 2008-01-10 Gkss-Forschungszentrum Geesthacht Gmbh Verfahren zum Herstellen von Nanopartikeln unter Verwendung poröser Membranen
US7674608B2 (en) 2007-02-23 2010-03-09 The University Of Toledo Saccharifying cellulose
EP2137318A4 (de) 2007-03-14 2012-01-04 Univ Toledo Vorbehandlung von biomasse
US7999355B2 (en) * 2008-07-11 2011-08-16 Air Products And Chemicals, Inc. Aminosilanes for shallow trench isolation films
CN103140540B (zh) * 2010-09-28 2014-07-23 东丽株式会社 聚合物微粒的制造方法
CA2959660A1 (en) 2014-09-03 2016-03-10 Genesegues, Inc. Therapeutic nanoparticles and related compositions, methods, and systems
KR102643181B1 (ko) 2016-02-29 2024-03-06 미첼만, 인크. 생분해성 중합체의 가수분해에 안정한 수계 분산물
WO2021006269A1 (ja) * 2019-07-10 2021-01-14 大日精化工業株式会社 樹脂ビーズの製造方法、樹脂ビーズ、及び樹脂ビーズを用いた製品
JP6872068B1 (ja) 2020-09-01 2021-05-19 大日精化工業株式会社 樹脂ビーズ、樹脂ビーズの製造方法、及び樹脂ビーズを用いた製品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2809192A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Method of making cellulose esters in the form of small, dense, spherical particles
US2809120A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Cellulose ester compositions
FR1264953A (fr) * 1960-08-11 1961-06-23 Basf Ag Procédé pour la production de matières plastiques sous forme de perles
US3485651A (en) * 1967-12-18 1969-12-23 Hercules Inc Water-soluble cellulose ether or starch compositions
US4462839A (en) * 1983-06-16 1984-07-31 Fmc Corporation Enteric coating for pharmaceutical dosage forms
DE3344242A1 (de) * 1983-12-07 1985-06-20 Wacker-Chemie GmbH, 8000 München Verfahren zur herstellung eines redispergierbaren dispersionspulvers und seine anwendung
CA1235119A (en) * 1984-01-24 1988-04-12 Kazuhiro Yamazaki Porous spherical cellulose acetate particles

Also Published As

Publication number Publication date
JPH01502991A (ja) 1989-10-12
EP0309527A1 (de) 1989-04-05
CA1340020C (en) 1998-09-01
IE881026L (en) 1988-10-16
BR8806902A (pt) 1989-10-31
IE62111B1 (en) 1994-12-14
DK173005B1 (da) 1999-11-01
ES2035949T3 (es) 1993-05-01
DE3877678D1 (de) 1993-03-04
ATE84806T1 (de) 1993-02-15
NO885570D0 (no) 1988-12-15
DK698688D0 (da) 1988-12-15
WO1988008011A1 (en) 1988-10-20
FI96219C (fi) 1996-05-27
AU1680688A (en) 1988-11-04
JP2564386B2 (ja) 1996-12-18
FI885767A0 (fi) 1988-12-13
EP0363549A1 (de) 1990-04-18
EP0309527B1 (de) 1993-01-20
AU610594B2 (en) 1991-05-23
NO174208C (no) 1994-03-30
FI885767A (fi) 1988-12-13
NO885570L (no) 1989-02-14
FI96219B (fi) 1996-02-15
NO174208B (no) 1993-12-20
EP0363549B1 (de) 1992-12-09
US4968350A (en) 1990-11-06
DK698688A (da) 1988-12-15
GR3006969T3 (de) 1993-06-30

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee