|
USRE28819E
(en)
|
1972-12-08 |
1976-05-18 |
Syntex (U.S.A.) Inc. |
Dialkylated glycol compositions and medicament preparations containing same
|
|
US4255329A
(en)
|
1973-10-02 |
1981-03-10 |
Syva Company |
Double receptor fluorescent immunoassay
|
|
US4117149A
(en)
|
1975-09-12 |
1978-09-26 |
Pfizer Inc. |
4-oxo-4h-benzopyrans as animal growth promotants
|
|
US4261928A
(en)
|
1977-08-05 |
1981-04-14 |
Sterling Drug Inc. |
2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
|
|
US4171365A
(en)
|
1977-08-05 |
1979-10-16 |
Sterling Drug Inc. |
Antiviral aryloxyalkylpyrazoles
|
|
US4234725A
(en)
|
1979-10-24 |
1980-11-18 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
|
|
US4232161A
(en)
|
1979-10-24 |
1980-11-04 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
|
|
US4328245A
(en)
|
1981-02-13 |
1982-05-04 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4410545A
(en)
|
1981-02-13 |
1983-10-18 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4358603A
(en)
|
1981-04-16 |
1982-11-09 |
Syntex (U.S.A.) Inc. |
Acetal stabilized prostaglandin compositions
|
|
US4668640A
(en)
|
1981-12-11 |
1987-05-26 |
Abbott Laboratories |
Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
|
|
US4409239A
(en)
|
1982-01-21 |
1983-10-11 |
Syntex (U.S.A.) Inc. |
Propylene glycol diester solutions of PGE-type compounds
|
|
GB2120242A
(en)
|
1982-04-30 |
1983-11-30 |
Erba Farmitalia |
Ergoline derivatives
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4764521A
(en)
|
1983-07-18 |
1988-08-16 |
Eli Lilly And Company |
Leukotriene antagonists and a method of use there as
|
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
|
US5315015A
(en)
|
1992-11-10 |
1994-05-24 |
Hoffmann-La Roche Inc. |
Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
|
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
|
WO1994022857A1
(fr)
|
1993-04-07 |
1994-10-13 |
Taiho Pharmaceutical Co., Ltd. |
Derive de thiazolidine et composition pharmaceutique contenant ce derive
|
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
|
NZ334914A
(en)
|
1996-10-01 |
2000-09-29 |
Stanford Res Inst Int |
Taste-masked microcapsule compositions and methods of manufacture using a phase seperation-coacervation technique
|
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
|
KR100719273B1
(ko)
|
1997-10-28 |
2007-05-18 |
반도 카가쿠 가부시키가이샤 |
피부 패치 시트 및 그것을 위한 베이스 시트의 제조 방법
|
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
|
NZ519984A
(en)
|
2000-01-07 |
2004-03-26 |
Transform Pharmaceuticals Inc |
High-throughput formation, identification, and analysis of diverse solid-forms
|
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
|
WO2003043998A1
(en)
|
2001-11-15 |
2003-05-30 |
Incyte San Diego Incorporated |
N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases
|
|
AU2003249678B2
(en)
|
2002-05-31 |
2009-03-19 |
Protamed, Inc. |
Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes, and Parkinson's disease
|
|
WO2004096808A1
(en)
|
2003-04-28 |
2004-11-11 |
De Novo Pharmaceuticals Limited |
Triazine compounds and their use
|
|
EP1750862B1
(en)
|
2004-06-04 |
2011-01-05 |
Teva Pharmaceutical Industries Ltd. |
Pharmaceutical composition containing irbesartan
|
|
WO2006009826A1
(en)
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
JP2007284350A
(ja)
|
2004-07-27 |
2007-11-01 |
Takeda Chem Ind Ltd |
糖尿病治療剤
|
|
WO2006088694A1
(en)
|
2005-02-14 |
2006-08-24 |
Wyeth |
SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS
|
|
WO2007012022A2
(en)
|
2005-07-18 |
2007-01-25 |
Horizon Therapeutics, Inc. |
Unit dose form with ibuprofen-famotidine admixture
|
|
EP2102165A2
(en)
|
2006-11-24 |
2009-09-23 |
AC Immune S.A. |
N-(methyl)-1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimer's
|
|
EA200900821A1
(ru)
|
2006-12-22 |
2010-02-26 |
Новартис Аг |
Производные 1-аминометил-l-фенилциклогексана как ингибиторы дпп-iv (дипептидилпептидазы-iv)
|
|
DK2155717T3
(da)
|
2007-05-11 |
2012-11-19 |
Lilly Co Eli |
2-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenyl-pyraziner og -pyridiner og 3-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-2-phenyl-pyridiner som 5-ht7-receptorantagonister
|
|
KR20100017372A
(ko)
|
2007-05-25 |
2010-02-16 |
애보트 게엠베하 운트 콤파니 카게 |
향대사성 글루타메이트 수용체 2（ｍｇｌｕ2 수용체）의 포지티브 조절자로서의 헤테로사이클릭 화합물
|
|
EA019084B1
(ru)
|
2007-06-06 |
2014-01-30 |
Торрент Фармасьютикалс Лтд. |
Новые тиреоидные соединения для лечения заболеваний, связанных с нарушением обмена веществ
|
|
MX2009013213A
(es)
|
2007-06-08 |
2010-03-30 |
Abbott Lab |
Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa.
|
|
AU2008345225A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
PT2260020E
(pt)
|
2008-03-26 |
2014-10-28 |
Novartis Ag |
Inibidores das desacetilases b baseados no hidroxamato
|
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
|
US8048887B2
(en)
|
2008-09-11 |
2011-11-01 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
US7994171B2
(en)
|
2008-09-11 |
2011-08-09 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
MX344354B
(es)
|
2008-10-20 |
2016-12-14 |
Alnylam Pharmaceuticals Inc |
Composiciones y metodos para inhibir la expresion de transtiretina.
|
|
AR074199A1
(es)
|
2008-11-20 |
2010-12-29 |
Glaxosmithkline Llc |
Compuesto de 6-(4-pirimidinil)-1h-indazol, composiciones farmaceuticas que lo comprenden y su uso para preparar un medicamento util para el tratamiento o disminucion de la gravedad del cancer.
|
|
CN104945382B
(zh)
|
2009-10-14 |
2020-02-07 |
默沙东公司 |
提高p53活性的取代的哌啶和其用途
|
|
AR079022A1
(es)
|
2009-11-02 |
2011-12-21 |
Sanofi Aventis |
Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
|
|
RS62767B1
(sr)
|
2010-04-07 |
2022-01-31 |
Vertex Pharma |
Farmaceutski sastavi 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il) ciklopropankarboksamido)-3-metilpiriodin-2-il)benzojeve kiseline i njihova primena
|
|
WO2011140333A1
(en)
|
2010-05-07 |
2011-11-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Identification of stabilizers of multimeric proteins
|
|
EP2651957B1
(en)
|
2010-12-16 |
2015-02-18 |
Allergan, Inc. |
Phosphorous derivatives as chemokine receptor modulators
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
WO2016025129A1
(en)
|
2014-08-14 |
2016-02-18 |
Alhamadsheh Mamoun M |
Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
|
|
ES2945345T3
(es)
|
2015-06-30 |
2023-06-30 |
Gilead Sciences Inc |
Formulaciones farmacéuticas
|
|
UA121775C2
(uk)
|
2015-07-31 |
2020-07-27 |
Пфайзер Інк. |
1,1,1-трифтор-3-гідроксипропан-2-ілкарбаматні похідні та 1,1,1-трифтор-4-гідроксибутан-2-ілкарбаматні похідні як інгібітори magl
|
|
TW202332423A
(zh)
*
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
MX2021015220A
(es)
|
2017-02-17 |
2022-12-01 |
Eidos Therapeutics Inc |
Procesos para preparar ácido 3-(3-(3,5-dimetil-1h-pirazol-4-il)pro poxi)-4- 5-fluorobenzoico (ag-10), sus compuestos intermedios, y sales del mismo.
|
|
CA3094711A1
(en)
|
2018-03-23 |
2019-09-26 |
Eidos Therapeutics, Inc. |
Methods of treating ttr amyloidosis using ag10
|
|
WO2020037189A1
(en)
|
2018-08-17 |
2020-02-20 |
Eidos Therapeutics, Inc. |
Formulations of ag10
|