|
USRE28819E
(en)
|
1972-12-08 |
1976-05-18 |
Syntex (U.S.A.) Inc. |
Dialkylated glycol compositions and medicament preparations containing same
|
|
US4255329A
(en)
|
1973-10-02 |
1981-03-10 |
Syva Company |
Double receptor fluorescent immunoassay
|
|
US4117149A
(en)
|
1975-09-12 |
1978-09-26 |
Pfizer Inc. |
4-oxo-4h-benzopyrans as animal growth promotants
|
|
US4171365A
(en)
|
1977-08-05 |
1979-10-16 |
Sterling Drug Inc. |
Antiviral aryloxyalkylpyrazoles
|
|
US4261928A
(en)
|
1977-08-05 |
1981-04-14 |
Sterling Drug Inc. |
2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
|
|
US4232161A
(en)
|
1979-10-24 |
1980-11-04 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
|
|
US4234725A
(en)
|
1979-10-24 |
1980-11-18 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
|
|
US4328245A
(en)
|
1981-02-13 |
1982-05-04 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4410545A
(en)
|
1981-02-13 |
1983-10-18 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4358603A
(en)
|
1981-04-16 |
1982-11-09 |
Syntex (U.S.A.) Inc. |
Acetal stabilized prostaglandin compositions
|
|
US4668640A
(en)
|
1981-12-11 |
1987-05-26 |
Abbott Laboratories |
Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
|
|
US4409239A
(en)
|
1982-01-21 |
1983-10-11 |
Syntex (U.S.A.) Inc. |
Propylene glycol diester solutions of PGE-type compounds
|
|
GB2120242A
(en)
|
1982-04-30 |
1983-11-30 |
Erba Farmitalia |
Ergoline derivatives
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4764521A
(en)
|
1983-07-18 |
1988-08-16 |
Eli Lilly And Company |
Leukotriene antagonists and a method of use there as
|
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
|
US5315015A
(en)
|
1992-11-10 |
1994-05-24 |
Hoffmann-La Roche Inc. |
Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
|
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
|
EP0645387A1
(fr)
|
1993-04-07 |
1995-03-29 |
Taiho Pharmaceutical Co., Ltd. |
Derive de thiazolidine et composition pharmaceutique contenant ce derive
|
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
|
BR9711585A
(pt)
|
1996-10-01 |
2000-01-18 |
Cima Labs Inc |
Composição de microcápsula, com sabor mascarado, de um remédio solúvel em água, formulação farmacêutica para administrar um remédio, e, processo para disfarçar o sabor de um remédio.
|
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
|
WO1999021537A1
(fr)
|
1997-10-28 |
1999-05-06 |
Bando Chemical Industries, Ltd. |
Feuille de timbre cutane et procede de production d'une feuille de base pour timbre
|
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
|
KR20020071931A
(ko)
|
2000-01-07 |
2002-09-13 |
트렌스폼 파마수티컬스 인코퍼레이티드 |
다양한 고체-형태들의 고도의 자료 처리 편성, 확인 및분석
|
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
|
EP1456187A4
(fr)
|
2001-11-15 |
2005-02-09 |
Incyte San Diego Inc |
Heterocycles n-substitues pour le traitement de l'hypercholesterolemie, de la dyslipidemie et autres troubles du metabolisme, du cancer et de pathologies diverses
|
|
ES2473581T3
(es)
|
2002-05-31 |
2014-07-07 |
Proteotech Inc. |
Compuestos, composiciones y métodos para el tratamiento de amiloidosis y sinucleinopat�as tales como la enfermedad de Alzheimer, la diabetes de tipo 2 y la enfermedad de Parkinson
|
|
WO2004096808A1
(fr)
|
2003-04-28 |
2004-11-11 |
De Novo Pharmaceuticals Limited |
Composes de triazine et leur utilisation
|
|
DE602005025755D1
(de)
|
2004-06-04 |
2011-02-17 |
Teva Pharma |
Irbesartan enthaltende pharmazeutische zusammensetzung
|
|
US8026366B2
(en)
|
2004-06-18 |
2011-09-27 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
JP2007284350A
(ja)
|
2004-07-27 |
2007-11-01 |
Takeda Chem Ind Ltd |
糖尿病治療剤
|
|
WO2006088694A1
(fr)
|
2005-02-14 |
2006-08-24 |
Wyeth |
THIÉNYL- ET FURYLACYLGUANIDINE SUBSTITUÉES ET MÉTHODES D'EMPLOI DESDITS COMPOSÉS EN TANT QUE RÉGULATEURS DE LA β-SECRÉTASE
|
|
CN101257800B
(zh)
*
|
2005-07-18 |
2012-07-18 |
好利用医疗公司 |
包含法莫替丁和布洛芬的药物
|
|
JP5292300B2
(ja)
|
2006-11-24 |
2013-09-18 |
エーシー イミューン ソシエテ アノニム |
例えばアルツハイマー病のようなアミロイドまたはアミロイド様タンパク質に関連する疾患の治療のためのｎ−（メチル）−１ｈ−ピラゾール−３−アミン誘導体、ｎ−（メチル）−ピリジン−２−アミン誘導体、およびｎ−（メチル）−トリゾール−２−アミン誘導体
|
|
KR20090096636A
(ko)
|
2006-12-22 |
2009-09-11 |
노파르티스 아게 |
Ｄｄｐ-ｉｖ 억제제로서의 1-아미노메틸-ｌ-페닐-시클로헥산 유도체
|
|
WO2008141020A1
(fr)
|
2007-05-11 |
2008-11-20 |
Eli Lilly And Company |
2-[4-(pyrazol-4-ylalkyl)pipérazin-1-yl]-3-phényl pyrazines et pyridines et 3-[4-(pyrazol-4-ylalkyl)pipérazin-1-yl]-2-phényl pyridines comme antagonistes de récepteur 5-ht7
|
|
CA2686651C
(fr)
|
2007-05-25 |
2015-11-24 |
Abbott Gmbh & Co. Kg |
Composes heterocycliques comme modulateurs positifs du recepteur metabotropique du glutamate 2 (recepteur mglu2)
|
|
DK2061766T3
(da)
|
2007-06-06 |
2010-12-13 |
Torrent Pharmaceuticals Ltd |
Nye forbindelser
|
|
CN101790526A
(zh)
|
2007-06-08 |
2010-07-28 |
雅培制药有限公司 |
用作激酶抑制剂的5-杂芳基取代的吲唑化合物
|
|
WO2009086303A2
(fr)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Procédé permettant de modifier la durée de vie d'organismes eucaryotes
|
|
ES2519474T3
(es)
|
2008-03-26 |
2014-11-07 |
Novartis Ag |
Inhibidores de las desacetilasas B basados en hidroxamato
|
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
|
US8048887B2
(en)
|
2008-09-11 |
2011-11-01 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
US7994171B2
(en)
|
2008-09-11 |
2011-08-09 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
EA029762B1
(ru)
|
2008-10-20 |
2018-05-31 |
Элнилэм Фармасьютикалз, Инк. |
Композиции и способы для ингибирования экспрессии транстиретина
|
|
UY32251A
(es)
|
2008-11-20 |
2010-05-31 |
Glaxosmithkline Llc |
Compuestos quimicos
|
|
BR112012008849A2
(pt)
|
2009-10-14 |
2015-09-22 |
Schering Corp |
composto, composição farmacêutica, e, uso de um composto
|
|
AR079022A1
(es)
|
2009-11-02 |
2011-12-21 |
Sanofi Aventis |
Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
|
|
DK3150198T3
(da)
*
|
2010-04-07 |
2021-11-01 |
Vertex Pharma |
Farmaceutiske sammensætninger af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl)-cyclopropancarboxamido)-3-methylpyriodin-2-yl)benzoesyre og indgivelse deraf
|
|
EP2566333A4
(fr)
|
2010-05-07 |
2014-04-02 |
Univ Leland Stanford Junior |
Identification de stabilisants de protéines multimériques
|
|
WO2012082568A1
(fr)
|
2010-12-16 |
2012-06-21 |
Allergan, Inc. |
Dérivés phosphoreux en tant que modulateurs de récepteur de chimiokine
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
US20160045609A1
(en)
|
2014-08-14 |
2016-02-18 |
Mamoun M. Alhamadsheh |
Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
|
|
WO2017004244A1
(fr)
*
|
2015-06-30 |
2017-01-05 |
Gilead Sciences, Inc. |
Formulations pharmaceutiques comprenant du ténofovir et de l'emtricitabine
|
|
EP3328849B9
(fr)
|
2015-07-31 |
2021-01-06 |
Pfizer Inc. |
Dérivés de carbamate de 1,1,1-trifluoro-3-hydroxypropan-2-yle et dérivés de carbamate de 1,1,1-trifluoro-4-hydroxybutan-2-yle comme inhibiteurs de magl
|
|
TW202332423A
(zh)
*
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
MX2021015220A
(es)
|
2017-02-17 |
2022-12-01 |
Eidos Therapeutics Inc |
Procesos para preparar ácido 3-(3-(3,5-dimetil-1h-pirazol-4-il)pro poxi)-4- 5-fluorobenzoico (ag-10), sus compuestos intermedios, y sales del mismo.
|
|
SG11202009073WA
(en)
|
2018-03-23 |
2020-10-29 |
Eidos Therapeutics Inc |
Methods of treating ttr amyloidosis using ag10
|
|
EP3836920A4
(fr)
|
2018-08-17 |
2022-04-13 |
Eidos Therapeutics, Inc. |
Formules d'ag10
|