EA202190561A1 - Препараты ag10 - Google Patents

Препараты ag10

Info

Publication number
EA202190561A1
EA202190561A1 EA202190561A EA202190561A EA202190561A1 EA 202190561 A1 EA202190561 A1 EA 202190561A1 EA 202190561 A EA202190561 A EA 202190561A EA 202190561 A EA202190561 A EA 202190561A EA 202190561 A1 EA202190561 A1 EA 202190561A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutically acceptable
acceptable salt
tablet formulations
preparations
provides
Prior art date
Application number
EA202190561A
Other languages
English (en)
Inventor
Джеспер Джернелиус
Марк Майкл Меннинг
Original Assignee
Эйдос Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эйдос Терапьютикс, Инк. filed Critical Эйдос Терапьютикс, Инк.
Publication of EA202190561A1 publication Critical patent/EA202190561A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

В изобретении предлагаются таблетированные препараты с высокой нагрузкой AG10 или его фармацевтически приемлемой соли. В некоторых аспектах изобретения предлагаются таблетированные препараты AG10 или его фармацевтически приемлемой соли, содержащие по меньшей мере 40 мас.% или больше AG10 или его фармацевтически приемлемой соли и по меньшей мере один фармацевтический эксципиент, выбираемый из одного или более наполнителей, одного или более связующих агентов, одного или более дезинтегрирующих агентов и одного или более агентов, улучшающих скольжение.
EA202190561A 2018-08-17 2019-08-16 Препараты ag10 EA202190561A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862765154P 2018-08-17 2018-08-17
PCT/US2019/046789 WO2020037189A1 (en) 2018-08-17 2019-08-16 Formulations of ag10

Publications (1)

Publication Number Publication Date
EA202190561A1 true EA202190561A1 (ru) 2021-05-26

Family

ID=69524257

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202190561A EA202190561A1 (ru) 2018-08-17 2019-08-16 Препараты ag10

Country Status (15)

Country Link
US (1) US11260047B2 (ru)
EP (1) EP3836920A4 (ru)
JP (1) JP7469293B2 (ru)
KR (1) KR20210046708A (ru)
CN (1) CN112804998A (ru)
AU (1) AU2019321583A1 (ru)
BR (1) BR112020026493A2 (ru)
CA (1) CA3104695A1 (ru)
CL (1) CL2021000289A1 (ru)
EA (1) EA202190561A1 (ru)
IL (1) IL280906A (ru)
MA (1) MA53238A (ru)
MX (1) MX2021001761A (ru)
SG (1) SG11202101393PA (ru)
WO (1) WO2020037189A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018151815A1 (en) 2017-02-17 2018-08-23 Eidos Therapeutics, Inc. Processes for preparing ag-10, its intermediates, and salts thereof
WO2023052652A1 (en) 2021-10-01 2023-04-06 Sandoz Ag Crystalline form of acoramidis hydrochloride

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Also Published As

Publication number Publication date
BR112020026493A2 (pt) 2021-03-23
EP3836920A4 (en) 2022-04-13
MX2021001761A (es) 2021-04-19
WO2020037189A1 (en) 2020-02-20
AU2019321583A1 (en) 2021-01-21
CA3104695A1 (en) 2020-02-20
JP7469293B2 (ja) 2024-04-16
US11260047B2 (en) 2022-03-01
JP2021534189A (ja) 2021-12-09
KR20210046708A (ko) 2021-04-28
CN112804998A (zh) 2021-05-14
US20200054607A1 (en) 2020-02-20
EP3836920A1 (en) 2021-06-23
SG11202101393PA (en) 2021-03-30
CL2021000289A1 (es) 2021-08-27
US20220313661A1 (en) 2022-10-06
MA53238A (fr) 2022-04-13
TW202021583A (zh) 2020-06-16
IL280906A (en) 2021-04-29

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