EA202192129A1 - Концентрированные жидкие фармацевтические составы фуросемида и способы их введения - Google Patents
Концентрированные жидкие фармацевтические составы фуросемида и способы их введенияInfo
- Publication number
- EA202192129A1 EA202192129A1 EA202192129A EA202192129A EA202192129A1 EA 202192129 A1 EA202192129 A1 EA 202192129A1 EA 202192129 A EA202192129 A EA 202192129A EA 202192129 A EA202192129 A EA 202192129A EA 202192129 A1 EA202192129 A1 EA 202192129A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- furosemide
- methods
- pharmaceutical compositions
- liquid pharmaceutical
- administration
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
В настоящем изобретении частично раскрыты жидкие фармацевтические составы, содержащие фуросемид или его фармацевтически приемлемую соль, один или более фармацевтически приемлемых наполнителей и фармацевтически приемлемый буфер. Также раскрыты способы лечения застоя, отека, перегрузки жидкостью или гипертензии у нуждающегося в нем пациента.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962799215P | 2019-01-31 | 2019-01-31 | |
PCT/US2020/015799 WO2020160210A1 (en) | 2019-01-31 | 2020-01-30 | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202192129A1 true EA202192129A1 (ru) | 2021-10-19 |
Family
ID=69740677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202192129A EA202192129A1 (ru) | 2019-01-31 | 2020-01-30 | Концентрированные жидкие фармацевтические составы фуросемида и способы их введения |
Country Status (14)
Country | Link |
---|---|
US (4) | US11497755B2 (ru) |
EP (1) | EP3917495A1 (ru) |
JP (1) | JP7465881B2 (ru) |
KR (1) | KR20210150360A (ru) |
CN (1) | CN113747881B (ru) |
AU (1) | AU2020214314A1 (ru) |
BR (1) | BR112021014637A2 (ru) |
CA (1) | CA3128033A1 (ru) |
EA (1) | EA202192129A1 (ru) |
IL (1) | IL285073A (ru) |
MA (1) | MA54865A (ru) |
MX (1) | MX2021009084A (ru) |
SG (1) | SG11202108280RA (ru) |
WO (1) | WO2020160210A1 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3128033A1 (en) | 2019-01-31 | 2020-08-06 | Scpharmaceuticals Inc. | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663348A (en) | 1985-07-02 | 1987-05-05 | Warner-Lambert Co. | Furosemide salts and pharmaceutical preparations thereof |
US4698361A (en) | 1986-05-28 | 1987-10-06 | Schiena Michele G Di | Tris-chydroxymethyl) aminomethane salt of 4-chloro-N-furfuryl-5-sulfamoyl anthranilic acid and diuretic compositions containing the same |
DE3623620A1 (de) | 1986-07-12 | 1988-01-21 | Boehringer Mannheim Gmbh | Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung |
ES2076263T3 (es) * | 1989-08-21 | 1995-11-01 | American Cyanamid Co | Formulacion farmaceutica inyectable estable, para acido folico y sales de leucovorina y procedimiento. |
EP0586590B1 (en) | 1991-05-30 | 1999-07-07 | Abbott Laboratories | Reagents containing a nonspecific binding blocker in ion-capture binding assays |
US5633240A (en) | 1994-09-01 | 1997-05-27 | Academic Pharmaceuticals | Parenteral solutions containing metolazone |
IT1283608B1 (it) | 1996-04-17 | 1998-04-22 | Ricerche Di Schiena Snc Di Dr | Composizione farmaceutica per la terapia orale diuretica ed antiipertensiva. |
CN1068778C (zh) | 1998-05-15 | 2001-07-25 | 赵超英 | 救治用的药物组合物及其制备方法 |
DE602005009966D1 (de) | 2005-12-28 | 2008-11-06 | Sensile Pat Ag | Mikropumpe |
EA018258B1 (ru) | 2006-07-12 | 2013-06-28 | Юниверсити Оф Теннесси Рисерч Фаундейшн | Замещенный ациланилид и содержащие его композиции и способы лечения |
EP2022518A1 (en) | 2007-08-07 | 2009-02-11 | Sensile Pat AG | Modular drug delivery device for administering discrete doses of a medicament |
US7923447B2 (en) | 2008-03-17 | 2011-04-12 | Academic Pharmaceuticals Incorporated | Parenteral solutions containing metolazone |
GB2459983B (en) | 2008-05-16 | 2010-04-28 | Corthera Inc | Methods of treating dyspnea associated with acute heart failure |
MX340669B (es) | 2008-09-09 | 2016-07-20 | Cima Labs Inc | Formas farmaceuticas para compuestos debilmente ionizables. |
MX2012002762A (es) | 2009-09-04 | 2012-06-12 | Minipumps Llc | Parche cutaneo adhesivo con bomba para suministro subcutaneo de farmacos. |
AU2012325801B2 (en) | 2011-10-19 | 2016-05-12 | Mercator Medsystems, Inc. | Localized modulation of tissues and cells to enhance therapeutic effects including renal denervation |
CN103371967A (zh) * | 2012-04-17 | 2013-10-30 | 上海禾丰制药有限公司 | 呋塞米注射液及其制剂工艺 |
JP2015516441A (ja) * | 2012-05-18 | 2015-06-11 | ルオダ ファーマ ピーティーワイ リミテッド | 液体配合剤 |
AU2014248164B2 (en) | 2013-04-05 | 2019-05-23 | Scpharmaceuticals, Inc. | Pharmaceutical formulations for subcutaneous administration of furosemide |
WO2016067876A1 (ja) | 2014-10-29 | 2016-05-06 | 日産自動車株式会社 | 燃料電池用電極触媒、燃料電池用電極触媒層、その製造方法ならびに当該触媒層を用いる膜電極接合体および燃料電池 |
EP3893843A1 (en) | 2018-12-10 | 2021-10-20 | SQ Innovation AG | Pharmaceutical compositions of furosemide and uses thereof |
CN113271923A (zh) | 2019-01-04 | 2021-08-17 | Sq创新股份公司 | 呋塞米的药物组合物及其用途 |
WO2020141226A1 (en) | 2019-01-04 | 2020-07-09 | Sq Innovation Ag | Pharmaceutical compositions of torsemide and uses thereof |
CA3128033A1 (en) | 2019-01-31 | 2020-08-06 | Scpharmaceuticals Inc. | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
-
2020
- 2020-01-30 CA CA3128033A patent/CA3128033A1/en active Pending
- 2020-01-30 KR KR1020217027628A patent/KR20210150360A/ko unknown
- 2020-01-30 MA MA054865A patent/MA54865A/fr unknown
- 2020-01-30 MX MX2021009084A patent/MX2021009084A/es unknown
- 2020-01-30 AU AU2020214314A patent/AU2020214314A1/en active Pending
- 2020-01-30 WO PCT/US2020/015799 patent/WO2020160210A1/en unknown
- 2020-01-30 CN CN202080019588.9A patent/CN113747881B/zh active Active
- 2020-01-30 SG SG11202108280RA patent/SG11202108280RA/en unknown
- 2020-01-30 EP EP20708883.2A patent/EP3917495A1/en active Pending
- 2020-01-30 EA EA202192129A patent/EA202192129A1/ru unknown
- 2020-01-30 BR BR112021014637-7A patent/BR112021014637A2/pt unknown
- 2020-01-30 JP JP2021542438A patent/JP7465881B2/ja active Active
-
2021
- 2021-07-22 IL IL285073A patent/IL285073A/en unknown
-
2022
- 2022-02-18 US US17/675,043 patent/US11497755B2/en active Active
- 2022-08-02 US US17/879,041 patent/US11571434B2/en active Active
- 2022-08-05 US US17/817,731 patent/US11559535B2/en active Active
-
2023
- 2023-01-05 US US18/150,590 patent/US20230277558A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US11497755B2 (en) | 2022-11-15 |
US11559535B2 (en) | 2023-01-24 |
CN113747881A (zh) | 2021-12-03 |
SG11202108280RA (en) | 2021-08-30 |
AU2020214314A1 (en) | 2021-08-19 |
EP3917495A1 (en) | 2021-12-08 |
BR112021014637A2 (pt) | 2021-09-21 |
IL285073A (en) | 2021-09-30 |
US20220168323A1 (en) | 2022-06-02 |
US20220378806A1 (en) | 2022-12-01 |
US20230277558A1 (en) | 2023-09-07 |
US20220096500A1 (en) | 2022-03-31 |
CA3128033A1 (en) | 2020-08-06 |
US20220378805A1 (en) | 2022-12-01 |
JP7465881B2 (ja) | 2024-04-11 |
JP2022518900A (ja) | 2022-03-17 |
KR20210150360A (ko) | 2021-12-10 |
MX2021009084A (es) | 2021-10-26 |
US11571434B2 (en) | 2023-02-07 |
CN113747881B (zh) | 2024-05-14 |
MA54865A (fr) | 2022-05-04 |
WO2020160210A1 (en) | 2020-08-06 |
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