EA202192129A1 - Концентрированные жидкие фармацевтические составы фуросемида и способы их введения - Google Patents
Концентрированные жидкие фармацевтические составы фуросемида и способы их введенияInfo
- Publication number
- EA202192129A1 EA202192129A1 EA202192129A EA202192129A EA202192129A1 EA 202192129 A1 EA202192129 A1 EA 202192129A1 EA 202192129 A EA202192129 A EA 202192129A EA 202192129 A EA202192129 A EA 202192129A EA 202192129 A1 EA202192129 A1 EA 202192129A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- furosemide
- methods
- pharmaceutical compositions
- liquid pharmaceutical
- administration
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
В настоящем изобретении частично раскрыты жидкие фармацевтические составы, содержащие фуросемид или его фармацевтически приемлемую соль, один или более фармацевтически приемлемых наполнителей и фармацевтически приемлемый буфер. Также раскрыты способы лечения застоя, отека, перегрузки жидкостью или гипертензии у нуждающегося в нем пациента.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962799215P | 2019-01-31 | 2019-01-31 | |
PCT/US2020/015799 WO2020160210A1 (en) | 2019-01-31 | 2020-01-30 | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202192129A1 true EA202192129A1 (ru) | 2021-10-19 |
Family
ID=69740677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202192129A EA202192129A1 (ru) | 2019-01-31 | 2020-01-30 | Концентрированные жидкие фармацевтические составы фуросемида и способы их введения |
Country Status (14)
Country | Link |
---|---|
US (5) | US11998555B2 (ru) |
EP (1) | EP3917495A1 (ru) |
JP (1) | JP7465881B2 (ru) |
KR (1) | KR20210150360A (ru) |
CN (1) | CN113747881B (ru) |
AU (1) | AU2020214314A1 (ru) |
BR (1) | BR112021014637A2 (ru) |
CA (1) | CA3128033A1 (ru) |
EA (1) | EA202192129A1 (ru) |
IL (1) | IL285073A (ru) |
MA (1) | MA54865A (ru) |
MX (1) | MX2021009084A (ru) |
SG (1) | SG11202108280RA (ru) |
WO (1) | WO2020160210A1 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3917495A1 (en) | 2019-01-31 | 2021-12-08 | scPharmaceuticals Inc. | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663348A (en) | 1985-07-02 | 1987-05-05 | Warner-Lambert Co. | Furosemide salts and pharmaceutical preparations thereof |
US4698361A (en) | 1986-05-28 | 1987-10-06 | Schiena Michele G Di | Tris-chydroxymethyl) aminomethane salt of 4-chloro-N-furfuryl-5-sulfamoyl anthranilic acid and diuretic compositions containing the same |
DE3623620A1 (de) | 1986-07-12 | 1988-01-21 | Boehringer Mannheim Gmbh | Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung |
ES2076263T3 (es) * | 1989-08-21 | 1995-11-01 | American Cyanamid Co | Formulacion farmaceutica inyectable estable, para acido folico y sales de leucovorina y procedimiento. |
WO1992021769A1 (en) | 1991-05-30 | 1992-12-10 | Abbott Laboratories | Reagents containing a nonspecific binding blocker in ion-capture binding assays |
US5633240A (en) | 1994-09-01 | 1997-05-27 | Academic Pharmaceuticals | Parenteral solutions containing metolazone |
IT1283608B1 (it) | 1996-04-17 | 1998-04-22 | Ricerche Di Schiena Snc Di Dr | Composizione farmaceutica per la terapia orale diuretica ed antiipertensiva. |
CN1068778C (zh) | 1998-05-15 | 2001-07-25 | 赵超英 | 救治用的药物组合物及其制备方法 |
PL1803934T3 (pl) | 2005-12-28 | 2009-03-31 | Sensile Pat Ag | Mikropompa |
CA2658394C (en) | 2006-07-12 | 2016-08-16 | University Of Tennessee Research Foundation | Substituted acylanilides and methods of use thereof |
EP2022518A1 (en) | 2007-08-07 | 2009-02-11 | Sensile Pat AG | Modular drug delivery device for administering discrete doses of a medicament |
US7923447B2 (en) | 2008-03-17 | 2011-04-12 | Academic Pharmaceuticals Incorporated | Parenteral solutions containing metolazone |
NZ598709A (en) | 2008-05-16 | 2013-09-27 | Corthera Inc | Treating acute decompensated heart failure with relaxin |
CA2735660C (en) | 2008-09-09 | 2017-05-30 | Cima Labs Inc. | Dosage forms for weakly ionizable compounds |
EP2473226A1 (en) | 2009-09-04 | 2012-07-11 | Minipumps LLC | Adhesive skin patch with pump for subcutaneous drug delivery |
BR112014009634A2 (pt) | 2011-10-19 | 2017-05-09 | Mercator Medsystems Inc | preparação e agente terapêutico |
CN103371967A (zh) | 2012-04-17 | 2013-10-30 | 上海禾丰制药有限公司 | 呋塞米注射液及其制剂工艺 |
NZ701609A (en) | 2012-05-18 | 2016-09-30 | Luoda Pharma Pty Ltd | Liquid formulation comprising propylene glycol and an inodilator |
JP6415535B2 (ja) * | 2013-04-05 | 2018-10-31 | エスシーファーマシューティカルズ インコーポレイテッド | フロセミドの皮下投与用の医薬製剤 |
CA2966137C (en) | 2014-10-29 | 2024-01-23 | Nissan Motor Co., Ltd. | Electrode catalyst for fuel cell, electrode catalyst layer for fuel cell, method for producing the same, and membrane electrode assembly and fuel cell using the catalyst layer |
EP3893843A1 (en) | 2018-12-10 | 2021-10-20 | SQ Innovation AG | Pharmaceutical compositions of furosemide and uses thereof |
WO2020141226A1 (en) | 2019-01-04 | 2020-07-09 | Sq Innovation Ag | Pharmaceutical compositions of torsemide and uses thereof |
EP3906019A1 (en) | 2019-01-04 | 2021-11-10 | SQ Innovation AG | Pharmaceutical compositions of furosemide and uses thereof |
EP3917495A1 (en) | 2019-01-31 | 2021-12-08 | scPharmaceuticals Inc. | Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same |
-
2020
- 2020-01-30 EP EP20708883.2A patent/EP3917495A1/en active Pending
- 2020-01-30 WO PCT/US2020/015799 patent/WO2020160210A1/en unknown
- 2020-01-30 KR KR1020217027628A patent/KR20210150360A/ko unknown
- 2020-01-30 SG SG11202108280RA patent/SG11202108280RA/en unknown
- 2020-01-30 US US17/426,765 patent/US11998555B2/en active Active
- 2020-01-30 CA CA3128033A patent/CA3128033A1/en active Pending
- 2020-01-30 CN CN202080019588.9A patent/CN113747881B/zh active Active
- 2020-01-30 MX MX2021009084A patent/MX2021009084A/es unknown
- 2020-01-30 MA MA054865A patent/MA54865A/fr unknown
- 2020-01-30 AU AU2020214314A patent/AU2020214314A1/en active Pending
- 2020-01-30 BR BR112021014637-7A patent/BR112021014637A2/pt unknown
- 2020-01-30 JP JP2021542438A patent/JP7465881B2/ja active Active
- 2020-01-30 EA EA202192129A patent/EA202192129A1/ru unknown
-
2021
- 2021-07-22 IL IL285073A patent/IL285073A/en unknown
-
2022
- 2022-02-18 US US17/675,043 patent/US11497755B2/en active Active
- 2022-08-02 US US17/879,041 patent/US11571434B2/en active Active
- 2022-08-05 US US17/817,731 patent/US11559535B2/en active Active
-
2023
- 2023-01-05 US US18/150,590 patent/US20230277558A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US11559535B2 (en) | 2023-01-24 |
CN113747881B (zh) | 2024-05-14 |
US20220378806A1 (en) | 2022-12-01 |
US11571434B2 (en) | 2023-02-07 |
WO2020160210A1 (en) | 2020-08-06 |
MA54865A (fr) | 2022-05-04 |
US20220378805A1 (en) | 2022-12-01 |
US20230277558A1 (en) | 2023-09-07 |
US20220168323A1 (en) | 2022-06-02 |
JP7465881B2 (ja) | 2024-04-11 |
MX2021009084A (es) | 2021-10-26 |
AU2020214314A1 (en) | 2021-08-19 |
US20220096500A1 (en) | 2022-03-31 |
BR112021014637A2 (pt) | 2021-09-21 |
CA3128033A1 (en) | 2020-08-06 |
KR20210150360A (ko) | 2021-12-10 |
SG11202108280RA (en) | 2021-08-30 |
CN113747881A (zh) | 2021-12-03 |
EP3917495A1 (en) | 2021-12-08 |
US11497755B2 (en) | 2022-11-15 |
JP2022518900A (ja) | 2022-03-17 |
IL285073A (en) | 2021-09-30 |
US11998555B2 (en) | 2024-06-04 |
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