EA201990885A1 - Композиции, содержащие короткие пептиды, полученные из pedf, и их применение - Google Patents
Композиции, содержащие короткие пептиды, полученные из pedf, и их применениеInfo
- Publication number
- EA201990885A1 EA201990885A1 EA201990885A EA201990885A EA201990885A1 EA 201990885 A1 EA201990885 A1 EA 201990885A1 EA 201990885 A EA201990885 A EA 201990885A EA 201990885 A EA201990885 A EA 201990885A EA 201990885 A1 EA201990885 A1 EA 201990885A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pedf
- application
- compositions containing
- short peptides
- peptides obtained
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108090000102 pigment epithelium-derived factor Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Фармацевтическая композиция для лечения офтальмологического заболевания у субъекта включает пептид и фармацевтически приемлемый наполнитель, где пептид содержит последовательность SEQ ID NO: 1: S-X-X-A-X-Q/H-X-X-X-X-I/V-I-X-R, где каждый X независимо представляет собой любую аминокислоту.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662405522P | 2016-10-07 | 2016-10-07 | |
PCT/US2017/048340 WO2018067244A1 (en) | 2016-10-07 | 2017-08-24 | Compositions comprising pedf-derived short peptides and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201990885A1 true EA201990885A1 (ru) | 2019-08-30 |
EA037698B1 EA037698B1 (ru) | 2021-05-12 |
Family
ID=61831898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201990885A EA037698B1 (ru) | 2016-10-07 | 2017-08-24 | Композиции, содержащие короткие пептиды, полученные из pedf, и их применение |
Country Status (10)
Country | Link |
---|---|
US (1) | US11760784B2 (ru) |
EP (1) | EP3596104A4 (ru) |
JP (2) | JP2019533722A (ru) |
KR (2) | KR20230169375A (ru) |
CN (1) | CN110312732A (ru) |
AU (2) | AU2017340245B2 (ru) |
EA (1) | EA037698B1 (ru) |
IL (1) | IL265796A (ru) |
TW (1) | TW201822785A (ru) |
WO (2) | WO2018067244A1 (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2021521115A (ja) * | 2018-04-08 | 2021-08-26 | ブリム バイオテクノロジー インクBrim Biotechnology, Inc. | 変形性関節症の治療におけるpedf由来短鎖ペプチドの使用 |
TW202010513A (zh) * | 2018-04-08 | 2020-03-16 | 全福生物科技股份有限公司 | Pedf衍生之短肽在肌腱癒合中的應用 |
KR20210005696A (ko) * | 2018-05-04 | 2021-01-14 | 브림 바이오테크놀로지, 인코퍼레이티드 | 마이봄 샘 재생을 촉진하기 위한 pedf-유래 펩타이드 및 그것의 사용 |
CN111632128B (zh) * | 2019-02-14 | 2022-07-05 | 三凡生技研发股份有限公司 | 短链胜肽组合物在预防或治疗干眼症的应用 |
TWI759610B (zh) * | 2019-06-27 | 2022-04-01 | 晶碩光學股份有限公司 | 具有角膜修護功能的眼用產品 |
TWI744683B (zh) * | 2019-08-27 | 2021-11-01 | 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 | 短合成胜肽及其治療視網膜退化性疾病和/或組織損傷的用途 |
EP4021917A4 (en) * | 2019-08-27 | 2023-05-24 | Yeou-Ping Tsao | SHORT SYNTHETIC PEPTIDES AND THEIR USE IN THE TREATMENT OF RETINAL DEGENERATIVE DISEASES AND/OR TISSUE INJURIES |
CN115151243A (zh) * | 2019-10-06 | 2022-10-04 | 全福生物科技股份有限公司 | 包含pedf-衍生短肽(pdsp)的组合物及其用途 |
CN112206312A (zh) * | 2020-11-19 | 2021-01-12 | 北京大学第三医院(北京大学第三临床医学院) | 一种包含pedf的用于治疗干眼的药物组合物 |
CN115364199A (zh) * | 2021-05-19 | 2022-11-22 | 远大医药(中国)有限公司 | 包含pedf衍生的短肽的组合物及其制备方法和用途 |
TW202402320A (zh) * | 2022-06-13 | 2024-01-16 | 全福生物科技股份有限公司 | 用於治療乾眼疾病之包含pedf衍生短肽之組合物 |
TW202400628A (zh) * | 2022-06-24 | 2024-01-01 | 全福生物科技股份有限公司 | 用於治療神經營養性角膜炎疾病之包含pedf衍生短肽之組合物 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6451763B1 (en) * | 1992-06-04 | 2002-09-17 | The United States Of America As Represented By The Department Of Health And Human Services | Retinal pigmented epithelium derived neurotrophic factor and methods of use |
US6797691B1 (en) * | 1997-07-23 | 2004-09-28 | Northwestern University | Methods and compositions for inhibiting angiogenesis |
AU2004285562B2 (en) * | 2003-10-29 | 2011-06-09 | The Johns Hopkins University | Pigment epithelium-derived factor, novel biological activity and methods of use |
US20050260180A1 (en) * | 2004-03-12 | 2005-11-24 | Genvec, Inc. | Materials and methods for treating vascular leakage in the eye |
EP1986676A4 (en) * | 2006-02-15 | 2009-11-04 | Univ Yale Inc | COMPOSITIONS AND METHODS USING PIGMENT EPITHELIUM DERIVED FACTOR (PEDF) PEPTIDE FRAGMENTS |
US20130333068A1 (en) * | 2008-04-29 | 2013-12-12 | Marie Coffin | Genes and uses for plant enhancement |
JP2013507373A (ja) * | 2009-10-08 | 2013-03-04 | ニューロテック ユーエスエー, インコーポレイテッド | 被包された細胞ベースの送達系におけるpedfの使用 |
EP2508196B1 (en) * | 2011-03-23 | 2018-09-26 | Mackay Memorial Hospital | Use of PEDF-derived polypeptides for promoting stem cells proliferation and wound healing |
TWI554521B (zh) * | 2011-10-19 | 2016-10-21 | 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 | 色素上皮衍生因子衍生之多胜肽於治療禿髮和/或毛髮脫色之用途 |
CA2882479C (en) * | 2012-08-09 | 2018-07-24 | Yeou-Ping Tsao | Use of pedf-derived polypeptides for promoting muscle or tendon regeneration or arteriogenesis |
US9815878B2 (en) * | 2012-09-19 | 2017-11-14 | Mackay Memorial Hospital | Use of PEDF-derived polypeptides for preventing and/or ameliorating skin aging |
AU2012390210B2 (en) * | 2012-09-20 | 2017-06-29 | Mackay Memorial Hospital | Use of PEDF-derived polypeptides for treating osteoarthritis |
US9611314B2 (en) * | 2013-09-13 | 2017-04-04 | The Penn State Research Foundation | Functional peptide analogs of PEDF |
-
2017
- 2017-08-24 KR KR1020237039829A patent/KR20230169375A/ko active Application Filing
- 2017-08-24 AU AU2017340245A patent/AU2017340245B2/en active Active
- 2017-08-24 CN CN201780075291.2A patent/CN110312732A/zh active Pending
- 2017-08-24 EA EA201990885A patent/EA037698B1/ru unknown
- 2017-08-24 JP JP2019540514A patent/JP2019533722A/ja active Pending
- 2017-08-24 EP EP17858860.4A patent/EP3596104A4/en active Pending
- 2017-08-24 US US16/340,113 patent/US11760784B2/en active Active
- 2017-08-24 WO PCT/US2017/048340 patent/WO2018067244A1/en unknown
- 2017-08-24 KR KR1020197012272A patent/KR20190066030A/ko not_active Application Discontinuation
- 2017-09-29 TW TW106133749A patent/TW201822785A/zh unknown
- 2017-10-07 WO PCT/US2017/042474 patent/WO2018067217A2/en active Application Filing
-
2019
- 2019-04-03 IL IL265796A patent/IL265796A/en unknown
-
2022
- 2022-06-28 AU AU2022204557A patent/AU2022204557A1/en not_active Abandoned
- 2022-09-29 JP JP2022155973A patent/JP2022185042A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3596104A1 (en) | 2020-01-22 |
EP3596104A4 (en) | 2021-02-17 |
JP2022185042A (ja) | 2022-12-13 |
TW201822785A (zh) | 2018-07-01 |
WO2018067217A2 (en) | 2018-04-12 |
US20190248859A1 (en) | 2019-08-15 |
KR20190066030A (ko) | 2019-06-12 |
JP2019533722A (ja) | 2019-11-21 |
AU2017340245A1 (en) | 2019-05-23 |
US11760784B2 (en) | 2023-09-19 |
WO2018067244A1 (en) | 2018-04-12 |
CN110312732A (zh) | 2019-10-08 |
AU2017340245B2 (en) | 2022-07-21 |
AU2022204557A1 (en) | 2022-07-21 |
KR20230169375A (ko) | 2023-12-15 |
EA037698B1 (ru) | 2021-05-12 |
WO2018067217A3 (en) | 2019-05-02 |
IL265796A (en) | 2019-06-30 |
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