JP7469293B2 - Ａｇ１０の製剤 - Google Patents

Ａｇ１０の製剤 Download PDF

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Publication number
JP7469293B2
JP7469293B2 JP2021507989A JP2021507989A JP7469293B2 JP 7469293 B2 JP7469293 B2 JP 7469293B2 JP 2021507989 A JP2021507989 A JP 2021507989A JP 2021507989 A JP2021507989 A JP 2021507989A JP 7469293 B2 JP7469293 B2 JP 7469293B2
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tablet formulation
weight
fillers
tablet
pharma
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JP2021534189A (ja
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ジャーネリウス ジェスパー
マイケル メニング マーク
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エイドス セラピューティクス，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021507989A 2018-08-17 2019-08-16 Ａｇ１０の製剤 Active JP7469293B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024060790A JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862765154P 2018-08-17 2018-08-17
US62/765,154 2018-08-17
PCT/US2019/046789 WO2020037189A1 (en) 2018-08-17 2019-08-16 Formulations of ag10

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JP2024060790A Division JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

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JP2021534189A JP2021534189A (ja) 2021-12-09
JP7469293B2 true JP7469293B2 (ja) 2024-04-16

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JP2024060790A Pending JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

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EP (2) EP3836920B1 (enExample)
JP (2) JP7469293B2 (enExample)
KR (1) KR20210046708A (enExample)
CN (1) CN112804998A (enExample)
AU (2) AU2019321583C1 (enExample)
BR (1) BR112020026493A2 (enExample)
CA (1) CA3104695A1 (enExample)
CL (1) CL2021000289A1 (enExample)
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EA (1) EA202190561A1 (enExample)
FI (1) FI3836920T3 (enExample)
HR (1) HRP20251603T1 (enExample)
IL (1) IL280906B1 (enExample)
LT (1) LT3836920T (enExample)
MA (1) MA53238A (enExample)
MX (1) MX2021001761A (enExample)
PT (1) PT3836920T (enExample)
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SM (1) SMT202500463T1 (enExample)
TW (1) TWI834708B (enExample)
UA (1) UA128256C2 (enExample)
WO (1) WO2020037189A1 (enExample)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
MX2021015220A (es) 2017-02-17 2022-12-01 Eidos Therapeutics Inc Procesos para preparar ácido 3-(3-(3,5-dimetil-1h-pirazol-4-il)pro poxi)-4- 5-fluorobenzoico (ag-10), sus compuestos intermedios, y sales del mismo.
CA3094711A1 (en) 2018-03-23 2019-09-26 Eidos Therapeutics, Inc. Methods of treating ttr amyloidosis using ag10
WO2020037189A1 (en) 2018-08-17 2020-02-20 Eidos Therapeutics, Inc. Formulations of ag10
WO2023052652A1 (en) 2021-10-01 2023-04-06 Sandoz Ag Crystalline form of acoramidis hydrochloride
WO2025235883A1 (en) 2024-05-10 2025-11-13 Eidos Therapeutics, Inc. Acoramidis for use in the treatment of renal dysfunction

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JP2013523833A (ja) 2010-04-07 2013-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド ３−（６−（１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）シクロプロパンカルボキサミド）−３−メチルピリジン−２−イル）安息香酸の医薬組成物およびその投与
JP2016504338A (ja) 2012-12-21 2016-02-12 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ トランスサイレチン安定剤並びにトランスサイレチン・アミロイドーシス及びタンパク質−タンパク質相互作用を抑制するためのそれらの使用
US20180125789A1 (en) 2016-10-12 2018-05-10 Global Blood Therapeutics, Inc. Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
JP2018519297A (ja) 2015-06-30 2018-07-19 ギリアード サイエンシーズ， インコーポレイテッド テノホビルおよびエムトリシタビンを含む薬学的製剤

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JP2009501801A (ja) 2005-07-18 2009-01-22 ホライゾン セラピューティクス， インコーポレイテッド イブプロフェンとファモチジンとを含有する医薬およびその投与
JP2013523833A (ja) 2010-04-07 2013-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド ３−（６−（１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）シクロプロパンカルボキサミド）−３−メチルピリジン−２−イル）安息香酸の医薬組成物およびその投与
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JP2018519297A (ja) 2015-06-30 2018-07-19 ギリアード サイエンシーズ， インコーポレイテッド テノホビルおよびエムトリシタビンを含む薬学的製剤
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EP3836920A1 (en) 2021-06-23
EP3836920B1 (en) 2025-10-01
SG11202101393PA (en) 2021-03-30
WO2020037189A1 (en) 2020-02-20
UA128256C2 (uk) 2024-05-22
BR112020026493A2 (pt) 2021-03-23
KR20210046708A (ko) 2021-04-28
IL280906B1 (en) 2026-01-01
AU2025226697A1 (en) 2025-09-25
US20200054607A1 (en) 2020-02-20
TW202021583A (zh) 2020-06-16
FI3836920T3 (fi) 2025-12-22
EP4647068A2 (en) 2025-11-12
EA202190561A1 (ru) 2021-05-26
AU2019321583A1 (en) 2021-01-21
LT3836920T (lt) 2026-01-26
US12005043B2 (en) 2024-06-11
CA3104695A1 (en) 2020-02-20
IL280906A (en) 2021-04-29
HRP20251603T1 (hr) 2026-01-30
CN112804998A (zh) 2021-05-14
US20250057811A1 (en) 2025-02-20
JP2024083460A (ja) 2024-06-21
DK3836920T3 (da) 2025-12-22
MX2021001761A (es) 2021-04-19
SMT202500463T1 (it) 2026-01-12
US20220313661A1 (en) 2022-10-06
AU2019321583B2 (en) 2025-06-05
PT3836920T (pt) 2025-12-02
MA53238A (fr) 2022-04-13
NZ774039A (en) 2025-03-28
AU2019321583C1 (en) 2025-11-27
EP3836920A4 (en) 2022-04-13
JP2021534189A (ja) 2021-12-09
TWI834708B (zh) 2024-03-11
CL2021000289A1 (es) 2021-08-27
US11260047B2 (en) 2022-03-01

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