JP2023500793A5 - - Google Patents
Info
- Publication number
- JP2023500793A5 JP2023500793A5 JP2022522814A JP2022522814A JP2023500793A5 JP 2023500793 A5 JP2023500793 A5 JP 2023500793A5 JP 2022522814 A JP2022522814 A JP 2022522814A JP 2022522814 A JP2022522814 A JP 2022522814A JP 2023500793 A5 JP2023500793 A5 JP 2023500793A5
- Authority
- JP
- Japan
- Prior art keywords
- capsid protein
- sequence
- vector according
- raav vector
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025233417A JP2026041903A (ja) | 2019-10-16 | 2025-12-05 | アルツハイマー病に対する遺伝子治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962915988P | 2019-10-16 | 2019-10-16 | |
| US62/915,988 | 2019-10-16 | ||
| PCT/US2020/056051 WO2021076941A1 (en) | 2019-10-16 | 2020-10-16 | Gene therapy for alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025233417A Division JP2026041903A (ja) | 2019-10-16 | 2025-12-05 | アルツハイマー病に対する遺伝子治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023500793A JP2023500793A (ja) | 2023-01-11 |
| JP2023500793A5 true JP2023500793A5 (https=) | 2023-10-24 |
Family
ID=73288693
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022522814A Pending JP2023500793A (ja) | 2019-10-16 | 2020-10-16 | アルツハイマー病に対する遺伝子治療方法 |
| JP2025233417A Pending JP2026041903A (ja) | 2019-10-16 | 2025-12-05 | アルツハイマー病に対する遺伝子治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025233417A Pending JP2026041903A (ja) | 2019-10-16 | 2025-12-05 | アルツハイマー病に対する遺伝子治療方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230405148A1 (https=) |
| EP (1) | EP4045653A1 (https=) |
| JP (2) | JP2023500793A (https=) |
| KR (1) | KR20220082050A (https=) |
| CN (1) | CN114761569A (https=) |
| AU (2) | AU2020367437B2 (https=) |
| BR (1) | BR112022007010A2 (https=) |
| CA (1) | CA3157864A1 (https=) |
| CO (1) | CO2022006367A2 (https=) |
| IL (1) | IL292148A (https=) |
| MX (1) | MX2022004524A (https=) |
| WO (1) | WO2021076941A1 (https=) |
| ZA (1) | ZA202205344B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7616995B2 (ja) * | 2018-11-28 | 2025-01-17 | プリベイル セラピューティクス，インコーポレーテッド | 神経変性疾患のための遺伝子治療 |
| EP4065600A1 (en) | 2019-11-25 | 2022-10-05 | Cornell University | Apoe gene therapy |
| JP2025513066A (ja) * | 2022-04-12 | 2025-04-22 | ユニキュアー バイオファーマ ビー．ブイ． | Ａｐｏｅの核酸制御 |
| EP4551711A1 (en) * | 2022-07-08 | 2025-05-14 | Cornell University | Methods and pharmaceutical compositions for the treatment and the prevention of alzheimers disease |
| WO2025213111A2 (en) * | 2024-04-05 | 2025-10-09 | Cornell University | Aav expression of mirna to suppress human apoe mrna |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| AU4198793A (en) | 1992-07-24 | 1994-01-27 | Takeda Chemical Industries Ltd. | Microparticle preparation and production thereof |
| FR2695563B1 (fr) | 1992-09-11 | 1994-12-02 | Pasteur Institut | Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires. |
| ES2113094T3 (es) | 1993-03-09 | 1998-04-16 | Epic Therapeutics Inc | Las microparticulas macromoleculares y metodos de obtencion. |
| US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US5603960A (en) | 1993-05-25 | 1997-02-18 | O'hagan; Derek T. | Preparation of microparticles and method of immunization |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US6913767B1 (en) | 1993-10-25 | 2005-07-05 | Genentech, Inc. | Compositions for microencapsulation of antigens for use as vaccines |
| US5443505A (en) | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
| US6342390B1 (en) | 1994-11-23 | 2002-01-29 | The United States Of America As Represented By The Secretary Of Health And Human Services | Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy |
| EP0930874A2 (en) | 1996-10-09 | 1999-07-28 | Takeda Chemical Industries, Ltd. | A method for producing a microparticle |
| US6210707B1 (en) | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
| US6884435B1 (en) | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| US6406719B1 (en) | 1998-05-13 | 2002-06-18 | Microbiological Research Authority | Encapsulation of bioactive agents |
| GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
| US6264987B1 (en) | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| WO2005116204A1 (ja) * | 2004-05-11 | 2005-12-08 | Rnai Co., Ltd. | Ｒｎａ干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法 |
| US20070081972A1 (en) | 2005-09-30 | 2007-04-12 | The University Of Iowa Research Foundation | Polymer-based delivery system for immunotherapy of cancer |
| US20070248599A1 (en) * | 2006-02-21 | 2007-10-25 | Jordan Tang | Treatment of alzheimer's disease with inhibitors of apoe binding to apoe receptor |
| EP2114153B1 (en) * | 2007-02-06 | 2016-11-23 | Tai June Yoo | Treatment and prevention of neurodegenerative diseases using gene therapy |
| WO2012054425A2 (en) | 2010-10-18 | 2012-04-26 | University Of Iowa Research Foundation | Biodegradable particulate formulations |
| US9345776B2 (en) | 2011-02-24 | 2016-05-24 | The University Of Iowa Research Foundation | Biodegradable polymers with sulfenamide bonds for drug delivery applications |
| CN104540952A (zh) * | 2012-05-18 | 2015-04-22 | 衣阿华大学研究基金会 | 用于治疗淀粉状蛋白沉积的方法和组合物 |
| WO2013181618A2 (en) * | 2012-05-31 | 2013-12-05 | The Trustees Of Columbia University In The City Of New York | Methods to treat alzheimer's disease using apoe inhibitors |
| IL245703B (en) * | 2013-11-20 | 2022-07-01 | Univ Iowa Res Found | Methods and compositions for treating amyloid deposits |
| JP7610923B2 (ja) * | 2016-09-02 | 2025-01-09 | スパーク セラピューティクス インコーポレイテッド | Ｃｎｓ障害を治療するための方法及びベクター |
| US11071791B2 (en) * | 2018-01-26 | 2021-07-27 | Wisconsin Alumni Research Foundation | Vector for gene silencing and replacement and methods of use thereof |
| JP7616995B2 (ja) * | 2018-11-28 | 2025-01-17 | プリベイル セラピューティクス，インコーポレーテッド | 神経変性疾患のための遺伝子治療 |
-
2020
- 2020-10-16 JP JP2022522814A patent/JP2023500793A/ja active Pending
- 2020-10-16 WO PCT/US2020/056051 patent/WO2021076941A1/en not_active Ceased
- 2020-10-16 KR KR1020227016247A patent/KR20220082050A/ko active Pending
- 2020-10-16 AU AU2020367437A patent/AU2020367437B2/en active Active
- 2020-10-16 EP EP20804387.7A patent/EP4045653A1/en active Pending
- 2020-10-16 BR BR112022007010A patent/BR112022007010A2/pt unknown
- 2020-10-16 MX MX2022004524A patent/MX2022004524A/es unknown
- 2020-10-16 CN CN202080073402.8A patent/CN114761569A/zh active Pending
- 2020-10-16 CA CA3157864A patent/CA3157864A1/en active Pending
- 2020-10-16 US US17/769,255 patent/US20230405148A1/en active Pending
-
2022
- 2022-04-11 IL IL292148A patent/IL292148A/en unknown
- 2022-05-13 ZA ZA2022/05344A patent/ZA202205344B/en unknown
- 2022-05-16 CO CONC2022/0006367A patent/CO2022006367A2/es unknown
-
2025
- 2025-02-06 AU AU2025200812A patent/AU2025200812A1/en active Pending
- 2025-12-05 JP JP2025233417A patent/JP2026041903A/ja active Pending
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