JP2023534999A5 - - Google Patents
Info
- Publication number
- JP2023534999A5 JP2023534999A5 JP2023504171A JP2023504171A JP2023534999A5 JP 2023534999 A5 JP2023534999 A5 JP 2023534999A5 JP 2023504171 A JP2023504171 A JP 2023504171A JP 2023504171 A JP2023504171 A JP 2023504171A JP 2023534999 A5 JP2023534999 A5 JP 2023534999A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- aav
- mutation
- viral
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063055265P | 2020-07-22 | 2020-07-22 | |
| US63/055,265 | 2020-07-22 | ||
| US202063107394P | 2020-10-29 | 2020-10-29 | |
| US63/107,394 | 2020-10-29 | ||
| US202163183038P | 2021-05-02 | 2021-05-02 | |
| US63/183,038 | 2021-05-02 | ||
| PCT/US2021/042812 WO2022020616A1 (en) | 2020-07-22 | 2021-07-22 | Engineered muscle targeting compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023534999A JP2023534999A (ja) | 2023-08-15 |
| JP2023534999A5 true JP2023534999A5 (https=) | 2024-07-26 |
Family
ID=79728337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504171A Pending JP2023534999A (ja) | 2020-07-22 | 2021-07-22 | 操作された筋肉標的化組成物 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP4185702A4 (https=) |
| JP (1) | JP2023534999A (https=) |
| KR (1) | KR20230053591A (https=) |
| CN (1) | CN116194153A (https=) |
| AU (1) | AU2021314256A1 (https=) |
| BR (1) | BR112023000909A2 (https=) |
| CA (1) | CA3183530A1 (https=) |
| CL (2) | CL2023000204A1 (https=) |
| CO (1) | CO2023000866A2 (https=) |
| IL (1) | IL299431A (https=) |
| MX (1) | MX2023000998A (https=) |
| TW (1) | TW202217003A (https=) |
| WO (1) | WO2022020616A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12552838B2 (en) | 2020-04-20 | 2026-02-17 | Tenaya Therapeutics, Inc. | Adeno-associated virus with engineered capsid |
| US20240115734A1 (en) * | 2021-02-09 | 2024-04-11 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| CA3216419A1 (en) * | 2021-04-23 | 2022-10-27 | Greg NACHTRAB | Tissue-targeted modified aav capsids and methods of use thereof |
| JP2024530023A (ja) * | 2021-08-05 | 2024-08-14 | ザ・ブロード・インスティテュート・インコーポレイテッド | 操作された筋肉標的化組成物 |
| CN118202060A (zh) | 2021-10-05 | 2024-06-14 | 再生生物股份有限公司 | 用于重组aav生产的组合物和方法 |
| WO2023060113A1 (en) | 2021-10-05 | 2023-04-13 | Regenxbio Inc. | Compositions and methods for recombinant aav production |
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| EP4504952A4 (en) * | 2022-04-07 | 2026-04-08 | Kate Therapeutics Inc | COMPOSITIONS AND METHODS FOR MUSCULAR DISORDERS |
| WO2023198828A1 (en) * | 2022-04-13 | 2023-10-19 | Universitat Autònoma De Barcelona | Treatment of neuromuscular diseases via gene therapy that expresses klotho protein |
| ES3057171T3 (en) * | 2022-06-10 | 2026-02-26 | Genethon | Peptide-modified aav capsid with enhanced muscle transduction efficiency |
| EP4634394A2 (en) * | 2022-12-17 | 2025-10-22 | The Trustees of The University of Pennsylvania | Recombinant aav mutant vectors with cardiac and skeletal muscle-specific targeting motifs and compositions containing same |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| EP4680741A2 (en) | 2023-03-15 | 2026-01-21 | RegenxBio Inc. | Exon skipping gene therapy constructs, vectors and uses thereof |
| AU2024332181A1 (en) | 2023-08-31 | 2026-02-12 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2025090858A1 (en) * | 2023-10-27 | 2025-05-01 | Biogen Ma Inc. | Methods for identifying aav capsid variants with desired characteristics |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| US20250276095A1 (en) | 2024-03-04 | 2025-09-04 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of duchenne muscular dystrophy |
| WO2025250909A1 (en) | 2024-05-31 | 2025-12-04 | Sarepta Therapeutics, Inc. | Muscle-tropic recombinant aav |
| CN118667855A (zh) * | 2024-05-31 | 2024-09-20 | 扬州大学 | 一种具有肌肉靶向性促进骨形成的噬菌体的构建方法及其应用 |
| WO2026006341A1 (en) | 2024-06-24 | 2026-01-02 | Regenxbio Inc. | Microdystrophin gene therapy administration for treatment of dystrophinopathies |
| WO2026011009A1 (en) | 2024-07-02 | 2026-01-08 | Kate Therapeutics, Inc. | Compositions and methods for muscle disorders |
| WO2026030242A1 (en) | 2024-07-29 | 2026-02-05 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of facioscapulohumeral muscular dystrophy |
| WO2026030244A1 (en) | 2024-07-30 | 2026-02-05 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of limb girdle muscular dystrophy 2a |
| WO2026041758A1 (en) | 2024-08-22 | 2026-02-26 | Genethon | Modified aav capsid with enhanced transduction efficiency |
| WO2026050402A1 (en) | 2024-08-29 | 2026-03-05 | Kate Therapeutics, Inc. | Liver de-targeted muscle tropic capsids |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064739A1 (en) * | 2024-09-23 | 2026-03-26 | Carbon Biosciences, Inc. | Parvovirus compositions and related methods for gene therapy |
| WO2026069251A1 (en) * | 2024-09-30 | 2026-04-02 | Sarepta Therapeutics, Inc. | Adeno-associated virus capsid antibodies and fragments thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210363193A1 (en) * | 2018-04-27 | 2021-11-25 | Universität Heidelberg | Modified aav capsid polypeptides for treatment of muscular diseases |
| US12397084B2 (en) * | 2018-07-23 | 2025-08-26 | Georgia Tech Research Corporation | Synthetic hydrogel carriers for muscle repair |
| EP4028064A1 (en) * | 2019-09-12 | 2022-07-20 | The Broad Institute, Inc. | Engineered adeno-associated virus capsids |
-
2021
- 2021-07-22 KR KR1020237004484A patent/KR20230053591A/ko active Pending
- 2021-07-22 MX MX2023000998A patent/MX2023000998A/es unknown
- 2021-07-22 AU AU2021314256A patent/AU2021314256A1/en active Pending
- 2021-07-22 EP EP21846426.1A patent/EP4185702A4/en active Pending
- 2021-07-22 IL IL299431A patent/IL299431A/en unknown
- 2021-07-22 JP JP2023504171A patent/JP2023534999A/ja active Pending
- 2021-07-22 CA CA3183530A patent/CA3183530A1/en active Pending
- 2021-07-22 WO PCT/US2021/042812 patent/WO2022020616A1/en not_active Ceased
- 2021-07-22 CN CN202180054063.3A patent/CN116194153A/zh active Pending
- 2021-07-22 TW TW110126971A patent/TW202217003A/zh unknown
- 2021-07-22 BR BR112023000909A patent/BR112023000909A2/pt unknown
-
2023
- 2023-01-20 CL CL2023000204A patent/CL2023000204A1/es unknown
- 2023-01-26 CO CONC2023/0000866A patent/CO2023000866A2/es unknown
-
2024
- 2024-01-30 CL CL2024000275A patent/CL2024000275A1/es unknown
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