JP2023537625A5 - - Google Patents
Info
- Publication number
- JP2023537625A5 JP2023537625A5 JP2023511556A JP2023511556A JP2023537625A5 JP 2023537625 A5 JP2023537625 A5 JP 2023537625A5 JP 2023511556 A JP2023511556 A JP 2023511556A JP 2023511556 A JP2023511556 A JP 2023511556A JP 2023537625 A5 JP2023537625 A5 JP 2023537625A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- aav
- acid sequence
- amino acid
- encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063065616P | 2020-08-14 | 2020-08-14 | |
| US63/065,616 | 2020-08-14 | ||
| US202063109734P | 2020-11-04 | 2020-11-04 | |
| US63/109,734 | 2020-11-04 | ||
| PCT/US2021/045945 WO2022036220A1 (en) | 2020-08-14 | 2021-08-13 | Novel aav capsids and compositions containing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023537625A JP2023537625A (ja) | 2023-09-04 |
| JP2023537625A5 true JP2023537625A5 (https=) | 2024-08-13 |
Family
ID=77595666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023511556A Pending JP2023537625A (ja) | 2020-08-14 | 2021-08-13 | 新規ａａｖカプシド及びそれを含む組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230287451A1 (https=) |
| EP (1) | EP4196170A1 (https=) |
| JP (1) | JP2023537625A (https=) |
| KR (1) | KR20230051208A (https=) |
| CN (1) | CN116209769A (https=) |
| AU (1) | AU2021325954A1 (https=) |
| CA (1) | CA3188956A1 (https=) |
| IL (1) | IL300410A (https=) |
| MX (1) | MX2023001863A (https=) |
| TW (1) | TW202221127A (https=) |
| WO (1) | WO2022036220A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3216004A1 (en) | 2021-04-23 | 2022-10-27 | The Trustees Of The University Of Pennsylvania | Novel compositions with brain-specific targeting motifs and compositions containing same |
| CN119173269A (zh) * | 2022-03-03 | 2024-12-20 | 宾夕法尼亚州大学信托人 | 用于递送glp-1受体激动剂融合物的aav载体 |
| US20260021205A1 (en) * | 2022-07-15 | 2026-01-22 | The Trustees Of The University Of Pennsylvania | Recombinant aav having aav clade d and clade e capsids and compositions containing same |
| CN117801116A (zh) * | 2022-09-30 | 2024-04-02 | 上海玮美基因科技有限责任公司 | 一种融合型新型腺相关病毒及其应用 |
| WO2024130070A2 (en) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Recombinant aav capsids with cardiac- and skeletal muscle- specific targeting motifs and uses thereof |
| EP4634394A2 (en) | 2022-12-17 | 2025-10-22 | The Trustees of The University of Pennsylvania | Recombinant aav mutant vectors with cardiac and skeletal muscle-specific targeting motifs and compositions containing same |
| WO2024258961A1 (en) | 2023-06-12 | 2024-12-19 | The Trustees Of The University Of Pennsylvania | Aav gene therapy for mucopolysaccharidosis iiib |
| TW202516019A (zh) | 2023-06-29 | 2025-04-16 | 賓州大學委員會 | 具中樞神經系統靶向模體的突變aav及含有其之組成物 |
| WO2025039622A1 (zh) * | 2023-08-23 | 2025-02-27 | 上海金珂博生物技术有限公司 | 经修饰的腺相关病毒载体及其在治疗中枢神经系统疾病中的用途 |
| WO2025106661A1 (en) | 2023-11-14 | 2025-05-22 | The Trustees Of The University Of Pennsylvania | Compositions with cardiac and skeletal musclespecific targeting motifs and uses thereof |
| CN120677245A (zh) * | 2024-01-25 | 2025-09-19 | 鼐济医药科技(杭州)有限公司 | Aav载体、载体组合物、嵌合载体和治疗或预防sma的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| US6200560B1 (en) | 1998-10-20 | 2001-03-13 | Avigen, Inc. | Adeno-associated virus vectors for expression of factor VIII by target cells |
| US6221349B1 (en) | 1998-10-20 | 2001-04-24 | Avigen, Inc. | Adeno-associated vectors for expression of factor VIII by target cells |
| MX359371B (es) | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| PT1453547T (pt) | 2001-12-17 | 2016-12-28 | Univ Pennsylvania | Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas |
| EP1486567A1 (en) | 2003-06-11 | 2004-12-15 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Improved adeno-associated virus (AAV) vector for gene therapy |
| US8005620B2 (en) | 2003-08-01 | 2011-08-23 | Dna Twopointo Inc. | Systems and methods for biopolymer engineering |
| EP2434420A3 (en) | 2003-08-01 | 2012-07-25 | Dna Twopointo Inc. | Systems and methods for biopolymer engineering |
| EP2287323A1 (en) | 2009-07-31 | 2011-02-23 | Association Institut de Myologie | Widespread gene delivery to the retina using systemic administration of AAV vectors |
| WO2011126808A2 (en) | 2010-03-29 | 2011-10-13 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| FR2977562B1 (fr) | 2011-07-06 | 2016-12-23 | Gaztransport Et Technigaz | Cuve etanche et thermiquement isolante integree dans une structure porteuse |
| WO2013155222A2 (en) | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| WO2015012924A2 (en) | 2013-04-29 | 2015-01-29 | The Trustees Of The University Of Pennsylvania | Tissue preferential codon modified expression cassettes, vectors containing same, and use thereof |
| EP3134431B1 (en) | 2014-04-25 | 2021-04-07 | The Trustees Of The University Of Pennsylvania | Ldlr variants and their use in compositions for reducing cholesterol levels |
| EP3151866B1 (en) * | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
-
2021
- 2021-08-13 EP EP21763485.6A patent/EP4196170A1/en active Pending
- 2021-08-13 MX MX2023001863A patent/MX2023001863A/es unknown
- 2021-08-13 KR KR1020237007585A patent/KR20230051208A/ko active Pending
- 2021-08-13 CA CA3188956A patent/CA3188956A1/en active Pending
- 2021-08-13 JP JP2023511556A patent/JP2023537625A/ja active Pending
- 2021-08-13 WO PCT/US2021/045945 patent/WO2022036220A1/en not_active Ceased
- 2021-08-13 AU AU2021325954A patent/AU2021325954A1/en active Pending
- 2021-08-13 IL IL300410A patent/IL300410A/en unknown
- 2021-08-13 CN CN202180070175.8A patent/CN116209769A/zh active Pending
- 2021-08-13 US US18/040,648 patent/US20230287451A1/en active Pending
- 2021-08-13 TW TW110129927A patent/TW202221127A/zh unknown
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