JP2022530656A5 - - Google Patents
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- Publication number
- JP2022530656A5 JP2022530656A5 JP2021564543A JP2021564543A JP2022530656A5 JP 2022530656 A5 JP2022530656 A5 JP 2022530656A5 JP 2021564543 A JP2021564543 A JP 2021564543A JP 2021564543 A JP2021564543 A JP 2021564543A JP 2022530656 A5 JP2022530656 A5 JP 2022530656A5
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962840184P | 2019-04-29 | 2019-04-29 | |
| US62/840,184 | 2019-04-29 | ||
| US201962913314P | 2019-10-10 | 2019-10-10 | |
| US62/913,314 | 2019-10-10 | ||
| US201962924095P | 2019-10-21 | 2019-10-21 | |
| US62/924,095 | 2019-10-21 | ||
| PCT/US2020/030281 WO2020223236A1 (en) | 2019-04-29 | 2020-04-28 | Novel aav capsids and compositions containing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022530656A JP2022530656A (ja) | 2022-06-30 |
| JP2022530656A5 true JP2022530656A5 (https=) | 2023-04-18 |
| JPWO2020223236A5 JPWO2020223236A5 (https=) | 2023-04-18 |
Family
ID=73028724
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564269A Active JP7690401B2 (ja) | 2019-04-29 | 2020-04-28 | 新規ａａｖカプシドおよびそれを含む組成物 |
| JP2021564543A Pending JP2022530656A (ja) | 2019-04-29 | 2020-04-28 | 新規ａａｖカプシドおよびそれを含む組成物 |
| JP2021564542A Active JP7644026B2 (ja) | 2019-04-29 | 2020-04-28 | 新規ａａｖカプシドおよびそれを含む組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564269A Active JP7690401B2 (ja) | 2019-04-29 | 2020-04-28 | 新規ａａｖカプシドおよびそれを含む組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564542A Active JP7644026B2 (ja) | 2019-04-29 | 2020-04-28 | 新規ａａｖカプシドおよびそれを含む組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US12516352B2 (https=) |
| EP (3) | EP3976077A4 (https=) |
| JP (3) | JP7690401B2 (https=) |
| KR (3) | KR20220004695A (https=) |
| CN (3) | CN113853207A (https=) |
| AU (3) | AU2020264976A1 (https=) |
| BR (3) | BR112021020054A2 (https=) |
| CA (3) | CA3134379A1 (https=) |
| CL (3) | CL2021002768A1 (https=) |
| CO (3) | CO2021015928A2 (https=) |
| IL (3) | IL287492A (https=) |
| MX (3) | MX2021013267A (https=) |
| PE (3) | PE20220014A1 (https=) |
| PH (3) | PH12021552607A1 (https=) |
| SG (3) | SG11202111102SA (https=) |
| WO (3) | WO2020223231A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4085144A4 (en) | 2019-12-19 | 2024-03-27 | The Trustees of The University of Pennsylvania | COMPOSITIONS FOR THE TREATMENT OF FRIEDREICH AAXIA |
| US20230220069A1 (en) | 2020-06-17 | 2023-07-13 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of gene therapy patients |
| BR112023003310A2 (pt) | 2020-08-24 | 2023-05-02 | Univ Pennsylvania | Vetores virais que codificam fusões de agonistas do receptor de glp-1 e usos dos mesmos no tratamento de doenças metabólicas |
| WO2022094078A1 (en) | 2020-10-28 | 2022-05-05 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of rett syndrome |
| CA3201533A1 (en) | 2020-11-11 | 2022-05-19 | European Molecular Biology Laboratory | Modified viral particles for gene therapy |
| KR20230128001A (ko) * | 2020-12-01 | 2023-09-01 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 엔젤만 증후군의 치료를 위한 조성물 및 이의 용도 |
| TW202237850A (zh) | 2020-12-01 | 2022-10-01 | 賓州大學委員會 | 具有組織特異性靶向基序的新穎構成物及含有其之組成物 |
| AR125406A1 (es) | 2021-04-23 | 2023-07-12 | Univ Pennsylvania | Nuevas composiciones con motivos selectivos para el cerebro y composiciones que las contienen |
| US20250144243A1 (en) | 2022-01-25 | 2025-05-08 | The Trustees Of The University Of Pennsylvania | Aav capsids for improved heart transduction and detargeting of liver |
| WO2023168293A2 (en) * | 2022-03-01 | 2023-09-07 | The Trustees Of The University Of Pennsylvania | Viral vector genome encoding an insulin fusion protein |
| CA3245158A1 (en) * | 2022-03-03 | 2023-09-07 | The Trustees Of The University Of Pennsylvania | Viral vectors encoding parathyroid hormone fusions and uses thereof in treating hypoparathyroidism |
| JP2025512969A (ja) | 2022-04-06 | 2025-04-22 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | Ｈｅｒ２陽性転移性乳がん及び他のがんを治療するための組成物及び方法 |
| US20250250326A1 (en) | 2022-04-06 | 2025-08-07 | The Trustees Of The University Of Pennsylvania | Passive immunization with anti-aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors |
| WO2024015966A2 (en) * | 2022-07-15 | 2024-01-18 | The Trustees Of The University Of Pennsylvania | Recombinant aav having aav clade d and clade e capsids and compositions containing same |
| WO2024130070A2 (en) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Recombinant aav capsids with cardiac- and skeletal muscle- specific targeting motifs and uses thereof |
| KR20250135916A (ko) | 2022-12-17 | 2025-09-15 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 심장 및 골격근 특이적 표적화 모티프를 갖는 재조합 aav 돌연변이체 벡터 및 이를 포함하는 조성물 |
| EP4724085A1 (en) | 2023-06-12 | 2026-04-15 | The Trustees of The University of Pennsylvania | Aav gene therapy for mucopolysaccharidosis iiib |
| AR133098A1 (es) | 2023-06-29 | 2025-08-27 | Univ Pennsylvania | Aav mutante con motivos dirigidos al sistema nervioso central y composiciones que lo contienen |
| IL326390A (en) | 2023-08-10 | 2026-04-01 | Univ Pennsylvania | Compositions and methods for treating spinal muscular atrophy |
| WO2025102034A1 (en) | 2023-11-10 | 2025-05-15 | The Trustees Of The University Of Pennsylvania | Gene therapy for barth syndrome |
| WO2025106661A1 (en) | 2023-11-14 | 2025-05-22 | The Trustees Of The University Of Pennsylvania | Compositions with cardiac and skeletal musclespecific targeting motifs and uses thereof |
| GB202319008D0 (en) * | 2023-12-13 | 2024-01-24 | Ucl Business Ltd | AAV-mediated gene therapy of diseases caused by impaired function of GLDC |
| WO2025129157A1 (en) | 2023-12-15 | 2025-06-19 | The Trustees Of The University Of Pennsylvania | Gene therapy for treatment of canavan disease |
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| US6200560B1 (en) | 1998-10-20 | 2001-03-13 | Avigen, Inc. | Adeno-associated virus vectors for expression of factor VIII by target cells |
| NZ532635A (en) * | 2001-11-13 | 2007-05-31 | Univ Pennsylvania | A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method |
| DK2359869T3 (en) | 2001-12-17 | 2019-04-15 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof |
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| WO2006110689A2 (en) | 2005-04-07 | 2006-10-19 | The Trustees Of The University Of Pennsylvania | Method of increasing the function of an aav vector |
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| US8632764B2 (en) | 2008-04-30 | 2014-01-21 | University Of North Carolina At Chapel Hill | Directed evolution and in vivo panning of virus vectors |
| WO2010138263A2 (en) * | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Novel aav 's and uses thereof |
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| US20130023033A1 (en) | 2010-03-29 | 2013-01-24 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
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| US9719106B2 (en) | 2013-04-29 | 2017-08-01 | The Trustees Of The University Of Pennsylvania | Tissue preferential codon modified expression cassettes, vectors containing same, and uses thereof |
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| WO2020132455A1 (en) | 2018-12-21 | 2020-06-25 | The Trustees Of The University Of Pennsylvania | Compositions for drg-specific reduction of transgene expression |
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2020
- 2020-04-28 PE PE2021001788A patent/PE20220014A1/es unknown
- 2020-04-28 WO PCT/US2020/030266 patent/WO2020223231A1/en not_active Ceased
- 2020-04-28 CN CN202080032666.9A patent/CN113853207A/zh active Pending
- 2020-04-28 CN CN202080033196.8A patent/CN113853209B/zh active Active
- 2020-04-28 KR KR1020217038207A patent/KR20220004695A/ko active Pending
- 2020-04-28 WO PCT/US2020/030281 patent/WO2020223236A1/en not_active Ceased
- 2020-04-28 EP EP20798442.8A patent/EP3976077A4/en active Pending
- 2020-04-28 CA CA3134379A patent/CA3134379A1/en active Pending
- 2020-04-28 BR BR112021020054A patent/BR112021020054A2/pt unknown
- 2020-04-28 AU AU2020264976A patent/AU2020264976A1/en active Pending
- 2020-04-28 SG SG11202111102SA patent/SG11202111102SA/en unknown
- 2020-04-28 AU AU2020266523A patent/AU2020266523A1/en active Pending
- 2020-04-28 AU AU2020264975A patent/AU2020264975A1/en active Pending
- 2020-04-28 SG SG11202111373YA patent/SG11202111373YA/en unknown
- 2020-04-28 PE PE2021001789A patent/PE20212334A1/es unknown
- 2020-04-28 EP EP20798752.0A patent/EP3976078A4/en active Pending
- 2020-04-28 PH PH1/2021/552607A patent/PH12021552607A1/en unknown
- 2020-04-28 JP JP2021564269A patent/JP7690401B2/ja active Active
- 2020-04-28 PH PH1/2021/552540A patent/PH12021552540A1/en unknown
- 2020-04-28 JP JP2021564543A patent/JP2022530656A/ja active Pending
- 2020-04-28 MX MX2021013267A patent/MX2021013267A/es unknown
- 2020-04-28 BR BR112021020545A patent/BR112021020545A2/pt unknown
- 2020-04-28 US US17/605,874 patent/US12516352B2/en active Active
- 2020-04-28 US US17/605,868 patent/US12516351B2/en active Active
- 2020-04-28 CA CA3134468A patent/CA3134468A1/en active Pending
- 2020-04-28 MX MX2021013268A patent/MX2021013268A/es unknown
- 2020-04-28 CN CN202080032773.1A patent/CN113853208A/zh active Pending
- 2020-04-28 KR KR1020217037661A patent/KR20220004681A/ko active Pending
- 2020-04-28 PE PE2021001795A patent/PE20212267A1/es unknown
- 2020-04-28 US US17/605,881 patent/US20220249705A1/en not_active Abandoned
- 2020-04-28 EP EP20798753.8A patent/EP3962507A4/en not_active Withdrawn
- 2020-04-28 PH PH1/2021/552608A patent/PH12021552608A1/en unknown
- 2020-04-28 SG SG11202111375RA patent/SG11202111375RA/en unknown
- 2020-04-28 WO PCT/US2020/030273 patent/WO2020223232A1/en not_active Ceased
- 2020-04-28 MX MX2021013266A patent/MX2021013266A/es unknown
- 2020-04-28 JP JP2021564542A patent/JP7644026B2/ja active Active
- 2020-04-28 BR BR112021021502A patent/BR112021021502A2/pt unknown
- 2020-04-28 CA CA3134507A patent/CA3134507A1/en active Pending
- 2020-04-28 KR KR1020217037659A patent/KR20220004680A/ko not_active Withdrawn
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2021
- 2021-10-21 IL IL287492A patent/IL287492A/en unknown
- 2021-10-21 CL CL2021002768A patent/CL2021002768A1/es unknown
- 2021-10-21 IL IL287491A patent/IL287491A/en unknown
- 2021-10-21 IL IL287498A patent/IL287498A/en unknown
- 2021-10-26 CL CL2021002811A patent/CL2021002811A1/es unknown
- 2021-10-27 CL CL2021002824A patent/CL2021002824A1/es unknown
- 2021-11-25 CO CONC2021/0015928A patent/CO2021015928A2/es unknown
- 2021-11-25 CO CONC2021/0015916A patent/CO2021015916A2/es unknown
- 2021-11-25 CO CONC2021/0015924A patent/CO2021015924A2/es unknown