JP2022552892A5 - - Google Patents

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Publication number
JP2022552892A5
JP2022552892A5 JP2022523659A JP2022523659A JP2022552892A5 JP 2022552892 A5 JP2022552892 A5 JP 2022552892A5 JP 2022523659 A JP2022523659 A JP 2022523659A JP 2022523659 A JP2022523659 A JP 2022523659A JP 2022552892 A5 JP2022552892 A5 JP 2022552892A5
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JP
Japan
Application number
JP2022523659A
Other languages
Japanese (ja)
Other versions
JPWO2021080991A5 (https=
JP2022552892A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/056511 external-priority patent/WO2021080991A1/en
Publication of JP2022552892A publication Critical patent/JP2022552892A/ja
Publication of JPWO2021080991A5 publication Critical patent/JPWO2021080991A5/ja
Publication of JP2022552892A5 publication Critical patent/JP2022552892A5/ja
Pending legal-status Critical Current

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JP2022523659A 2019-10-21 2020-10-20 改善された産生収率および肝臓向性を有するaav3b変異体 Pending JP2022552892A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962924112P 2019-10-21 2019-10-21
US62/924,112 2019-10-21
US202063025753P 2020-05-15 2020-05-15
US63/025,753 2020-05-15
PCT/US2020/056511 WO2021080991A1 (en) 2019-10-21 2020-10-20 Aav3b variants with improved production yield and liver tropism

Publications (3)

Publication Number Publication Date
JP2022552892A JP2022552892A (ja) 2022-12-20
JPWO2021080991A5 JPWO2021080991A5 (https=) 2023-10-18
JP2022552892A5 true JP2022552892A5 (https=) 2023-10-18

Family

ID=75620806

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022523659A Pending JP2022552892A (ja) 2019-10-21 2020-10-20 改善された産生収率および肝臓向性を有するaav3b変異体

Country Status (7)

Country Link
US (1) US20230002788A1 (https=)
EP (1) EP4048681A4 (https=)
JP (1) JP2022552892A (https=)
AU (1) AU2020369508A1 (https=)
CA (1) CA3155016A1 (https=)
TW (1) TW202130653A (https=)
WO (1) WO2021080991A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113444785B (zh) * 2021-06-28 2022-06-21 甘肃农业大学 一种与仔猪C型产气荚膜梭菌感染性腹泻相关的ssc-miR-122-5p及其应用
WO2023049846A1 (en) * 2021-09-24 2023-03-30 The Trustees Of The University Of Pennsylvania Compositions useful for treatment of charcot-marie-tooth disease
US20250250326A1 (en) 2022-04-06 2025-08-07 The Trustees Of The University Of Pennsylvania Passive immunization with anti-aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156303A (en) * 1997-06-11 2000-12-05 University Of Washington Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
US7749492B2 (en) * 2001-01-05 2010-07-06 Nationwide Children's Hospital, Inc. AAV vectors and methods
AU2015335923B2 (en) * 2014-10-21 2021-04-29 University Of Massachusetts Recombinant AAV variants and uses thereof
US10081659B2 (en) * 2015-04-06 2018-09-25 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Adeno-associated vectors for enhanced transduction and reduced immunogenicity
FI3445773T3 (fi) * 2016-05-13 2023-03-30 4D Molecular Therapeutics Inc Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä
WO2018154462A2 (en) * 2017-02-22 2018-08-30 Crispr Therapeutics Ag Materials and methods for treatment of spinocerebellar ataxia type 2 (sca2) and other spinocerebellar ataxia type 2 protein (atxn2) gene related conditions or disorders
WO2018200419A1 (en) * 2017-04-23 2018-11-01 The Trustees Of The University Of Pennsylvania Viral vectors comprising engineered aav capsids and compositions containing the same
IL276859B2 (en) * 2018-02-27 2025-12-01 Univ Pennsylvania Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor
MX2020008932A (es) * 2018-02-27 2020-10-01 Univ Pennsylvania Novedosos vectores de virus adenoasociado (aav), vectores de aav que tienen una desamidacion reducida de la capside y usos de estos.

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