JP2023524061A5 - - Google Patents
Info
- Publication number
- JP2023524061A5 JP2023524061A5 JP2022566315A JP2022566315A JP2023524061A5 JP 2023524061 A5 JP2023524061 A5 JP 2023524061A5 JP 2022566315 A JP2022566315 A JP 2022566315A JP 2022566315 A JP2022566315 A JP 2022566315A JP 2023524061 A5 JP2023524061 A5 JP 2023524061A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- mutation
- polypeptide
- vector system
- aav9
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063019221P | 2020-05-01 | 2020-05-01 | |
| US63/019,221 | 2020-05-01 | ||
| US202063061517P | 2020-08-05 | 2020-08-05 | |
| US63/061,517 | 2020-08-05 | ||
| PCT/US2021/030298 WO2021222831A2 (en) | 2020-05-01 | 2021-04-30 | Engineered central nervous system compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023524061A JP2023524061A (ja) | 2023-06-08 |
| JP2023524061A5 true JP2023524061A5 (https=) | 2024-05-13 |
Family
ID=78373993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022566315A Withdrawn JP2023524061A (ja) | 2020-05-01 | 2021-04-30 | 操作された中枢神経系用組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230193316A1 (https=) |
| EP (1) | EP4143305A4 (https=) |
| JP (1) | JP2023524061A (https=) |
| CN (1) | CN115867646A (https=) |
| AU (1) | AU2021264061A1 (https=) |
| CA (1) | CA3176506A1 (https=) |
| WO (1) | WO2021222831A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113166208B (zh) | 2018-10-02 | 2024-11-22 | 沃雅戈治疗公司 | 重新定向aav衣壳的嗜性 |
| TWI900553B (zh) | 2020-05-13 | 2025-10-11 | 美商航海家醫療公司 | Aav蛋白殼之趨性重定向 |
| US20240115734A1 (en) * | 2021-02-09 | 2024-04-11 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| CA3216419A1 (en) * | 2021-04-23 | 2022-10-27 | Greg NACHTRAB | Tissue-targeted modified aav capsids and methods of use thereof |
| WO2022226375A1 (en) * | 2021-04-23 | 2022-10-27 | Locanabio, Inc. | Tissue-targeted modified aav capsids and methods of use thereof |
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| EP4426716A1 (en) | 2021-11-02 | 2024-09-11 | Voyager Therapeutics, Inc. | Aav capsid variants and uses thereof |
| US20260085284A1 (en) * | 2022-08-30 | 2026-03-26 | Shanghai Genemagic Biosciences Co., Ltd. | Method for trans-differentiating non-neuronal cells into neurons and use thereof |
| WO2024086747A1 (en) | 2022-10-19 | 2024-04-25 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2024238807A2 (en) | 2023-05-16 | 2024-11-21 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| TW202516019A (zh) * | 2023-06-29 | 2025-04-16 | 賓州大學委員會 | 具中樞神經系統靶向模體的突變aav及含有其之組成物 |
| AU2024332181A1 (en) | 2023-08-31 | 2026-02-12 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| CN117165677A (zh) * | 2023-11-03 | 2023-12-05 | 首都儿科研究所 | 检测生物标志物在制备神经管畸形疾病的产品的应用 |
| WO2025160155A1 (en) | 2024-01-22 | 2025-07-31 | The Broad Institute, Inc. | Epigenetic targeting of prion diseases |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160039877A1 (en) * | 2013-03-15 | 2016-02-11 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
| EP4344741A3 (en) * | 2014-11-21 | 2024-08-28 | The University of North Carolina at Chapel Hill | Aav vectors targeted to the central nervous system |
| BR112017022845A2 (pt) * | 2015-04-23 | 2018-07-17 | Nantomics, Llc | neoepítopos de câncer |
| KR102423442B1 (ko) * | 2015-12-11 | 2022-07-20 | 캘리포니아 인스티튜트 오브 테크놀로지 | 아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드 |
| US12043848B2 (en) * | 2017-10-16 | 2024-07-23 | Vigeneron Gmbh | AAV vectors |
| CA3100006A1 (en) * | 2018-05-11 | 2019-11-14 | Massachusetts Eye And Ear Infirmary | Altering tissue tropism of adeno-associated viruses |
| WO2020028751A2 (en) * | 2018-08-03 | 2020-02-06 | Voyager Therapeutics, Inc. | Aav variants with enhanced tropism |
| CN113166208B (zh) * | 2018-10-02 | 2024-11-22 | 沃雅戈治疗公司 | 重新定向aav衣壳的嗜性 |
| WO2023039480A2 (en) * | 2021-09-08 | 2023-03-16 | The Broad Institute, Inc. | Engineered central nervous system compositions |
-
2021
- 2021-04-30 WO PCT/US2021/030298 patent/WO2021222831A2/en not_active Ceased
- 2021-04-30 AU AU2021264061A patent/AU2021264061A1/en active Pending
- 2021-04-30 JP JP2022566315A patent/JP2023524061A/ja not_active Withdrawn
- 2021-04-30 CN CN202180042776.8A patent/CN115867646A/zh active Pending
- 2021-04-30 US US17/922,437 patent/US20230193316A1/en active Pending
- 2021-04-30 CA CA3176506A patent/CA3176506A1/en active Pending
- 2021-04-30 EP EP21795362.9A patent/EP4143305A4/en active Pending
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