JP2023529371A5 - - Google Patents
Info
- Publication number
- JP2023529371A5 JP2023529371A5 JP2022574541A JP2022574541A JP2023529371A5 JP 2023529371 A5 JP2023529371 A5 JP 2023529371A5 JP 2022574541 A JP2022574541 A JP 2022574541A JP 2022574541 A JP2022574541 A JP 2022574541A JP 2023529371 A5 JP2023529371 A5 JP 2023529371A5
- Authority
- JP
- Japan
- Prior art keywords
- dnaj
- fusion protein
- synuclein
- group
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063035297P | 2020-06-05 | 2020-06-05 | |
| US63/035,297 | 2020-06-05 | ||
| PCT/US2021/035958 WO2021248038A1 (en) | 2020-06-05 | 2021-06-04 | Compositions and methods for the treatment of synucleinopathies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023529371A JP2023529371A (ja) | 2023-07-10 |
| JP2023529371A5 true JP2023529371A5 (https=) | 2024-06-10 |
Family
ID=76708439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022574541A Pending JP2023529371A (ja) | 2020-06-05 | 2021-06-04 | シヌクレイノパチーの処置のための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230234997A1 (https=) |
| EP (1) | EP4161953A1 (https=) |
| JP (1) | JP2023529371A (https=) |
| CN (1) | CN116096737A (https=) |
| CA (1) | CA3183251A1 (https=) |
| WO (1) | WO2021248038A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024229777A1 (zh) * | 2023-05-11 | 2024-11-14 | 深圳先进技术研究院 | 一种aav载体及其应用 |
| CN116590342B (zh) * | 2023-05-11 | 2026-04-03 | 普递瑞(上海)医药有限公司 | 一种aav载体及其应用 |
| CN117402251B (zh) * | 2023-12-15 | 2024-02-23 | 中国医学科学院基础医学研究所 | 一种抗小g蛋白rbj的抗体及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8918616D0 (en) | 1989-08-15 | 1989-09-27 | Univ Glasgow | Herpes simplex virus type 1 mutant |
| US5804413A (en) | 1992-07-31 | 1998-09-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus strains for gene transfer |
| GB9415319D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | HSV viral vector |
| US5846782A (en) | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US6093570A (en) | 1995-06-07 | 2000-07-25 | The University Of North Carolina At Chapel Hill | Helper virus-free AAV production |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| AU8605598A (en) | 1997-07-31 | 1999-02-22 | University Of Pittsburgh | Targeted hsv vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| WO1999061601A2 (en) | 1998-05-28 | 1999-12-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aav5 vector and uses thereof |
| CN1246532A (zh) * | 1998-08-31 | 2000-03-08 | 复旦大学 | 人热休克关联蛋白编码序列、其编码的多肽及制备方法 |
| ATE318923T1 (de) | 2000-06-01 | 2006-03-15 | Univ North Carolina | Doppelsträngige parvovirus-vektoren |
| WO2002004482A1 (en) * | 2000-07-07 | 2002-01-17 | Panacea Pharmaceuticals, Inc. | Methods for preventing neural tissue damage and for the treatment of alpha-synuclein diseases |
| WO2002053703A2 (en) | 2001-01-05 | 2002-07-11 | Children's Hospital, Inc. | Aav2 vectors and methods |
| MX359371B (es) | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| PT1453547T (pt) | 2001-12-17 | 2016-12-28 | Univ Pennsylvania | Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas |
| EP2345731B1 (en) | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| JP5136766B2 (ja) | 2004-12-15 | 2013-02-06 | ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | キメラベクター |
| US20110201686A1 (en) * | 2006-06-23 | 2011-08-18 | Yousef Al-Abed | Inhibitors of ASS and Synuclein Aggregation |
| WO2010093784A2 (en) | 2009-02-11 | 2010-08-19 | The University Of North Carolina At Chapel Hill | Modified virus vectors and methods of making and using the same |
| EP2524037B1 (en) | 2010-01-12 | 2018-05-16 | The University Of North Carolina At Chapel Hill | Restrictive inverted terminal repeats for viral vectors |
| US9169492B2 (en) | 2010-02-05 | 2015-10-27 | The University Of North Carolina At Chapel Hill | Compositions and methods for enhanced parvovirus transduction |
| WO2014053879A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| US9758807B2 (en) * | 2012-12-05 | 2017-09-12 | SOLA Biosciences, LLC | Protein expression enhancing polypeptides |
| US11390899B2 (en) * | 2016-09-26 | 2022-07-19 | SOLA Biosciences, LLC | Cell-associated secretion-enhancing fusion proteins |
| US12162929B2 (en) * | 2018-02-19 | 2024-12-10 | New York University | Alpha-synuclein single domain antibodies |
| US20230173049A1 (en) * | 2019-12-31 | 2023-06-08 | The Johns Hopkins University | Fusion proteins and methods of use thereof |
-
2021
- 2021-06-04 CA CA3183251A patent/CA3183251A1/en active Pending
- 2021-06-04 US US18/007,978 patent/US20230234997A1/en active Pending
- 2021-06-04 CN CN202180058141.7A patent/CN116096737A/zh active Pending
- 2021-06-04 EP EP21736438.9A patent/EP4161953A1/en active Pending
- 2021-06-04 JP JP2022574541A patent/JP2023529371A/ja active Pending
- 2021-06-04 WO PCT/US2021/035958 patent/WO2021248038A1/en not_active Ceased
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