JP2023524024A5 - - Google Patents
Info
- Publication number
- JP2023524024A5 JP2023524024A5 JP2022566010A JP2022566010A JP2023524024A5 JP 2023524024 A5 JP2023524024 A5 JP 2023524024A5 JP 2022566010 A JP2022566010 A JP 2022566010A JP 2022566010 A JP2022566010 A JP 2022566010A JP 2023524024 A5 JP2023524024 A5 JP 2023524024A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- seq
- acid sequence
- vector
- capsid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063016507P | 2020-04-28 | 2020-04-28 | |
| US63/016,507 | 2020-04-28 | ||
| US202063077144P | 2020-09-11 | 2020-09-11 | |
| US63/077,144 | 2020-09-11 | ||
| PCT/US2021/028658 WO2021221995A1 (en) | 2020-04-28 | 2021-04-22 | Modified nucleic acids encoding aspartoacylase (aspa) and vector for gene therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524024A JP2023524024A (ja) | 2023-06-08 |
| JP2023524024A5 true JP2023524024A5 (https=) | 2024-05-01 |
| JP7821742B2 JP7821742B2 (ja) | 2026-02-27 |
Family
ID=78373856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022566010A Active JP7821742B2 (ja) | 2020-04-28 | 2021-04-22 | アスパルトアシラーゼ（ａｓｐａ）をコードする修飾核酸及び遺伝子治療のためのベクター |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230165977A1 (https=) |
| EP (1) | EP4142759A4 (https=) |
| JP (1) | JP7821742B2 (https=) |
| KR (1) | KR20230003012A (https=) |
| CN (1) | CN115461066B (https=) |
| AU (1) | AU2021263534A1 (https=) |
| BR (1) | BR112022021964A2 (https=) |
| CA (1) | CA3174070A1 (https=) |
| IL (1) | IL297605A (https=) |
| TW (1) | TW202206599A (https=) |
| WO (1) | WO2021221995A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3234809A1 (en) | 2021-10-20 | 2023-04-27 | Steven Goldman | Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss |
| EP4426331A1 (en) | 2021-11-02 | 2024-09-11 | University of Rochester | Tcf7l2 mediated remyelination in the brain |
| CN119213133B (zh) | 2022-05-16 | 2026-01-06 | 上海天泽云泰生物医药有限公司 | 用于治疗i型戊二酸尿症的重组aav载体 |
| EP4658294A2 (en) | 2023-02-02 | 2025-12-10 | University of Rochester | Competitive replacement of glial cells |
| WO2025090427A1 (en) | 2023-10-23 | 2025-05-01 | University Of Rochester | Glial-targeted relief of hyperexcitability in neurodegenerative diseases |
| WO2025129157A1 (en) * | 2023-12-15 | 2025-06-19 | The Trustees Of The University Of Pennsylvania | Gene therapy for treatment of canavan disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL156752A0 (en) | 2001-01-06 | 2004-02-08 | Gen Hospital Corp | Gene for identifying individuals with familial dysautonomia |
| EP2561073B1 (en) | 2010-04-23 | 2016-08-24 | University of Massachusetts | Cns targeting aav vectors and methods of use thereof |
| EP2900686B1 (en) | 2012-09-28 | 2020-06-10 | The University of North Carolina At Chapel Hill | Aav vectors targeted to oligodendrocytes |
| EP3364997B1 (en) * | 2015-10-22 | 2024-01-17 | University of Massachusetts | Aspartoacylase gene therapy in the treatment of canavan disease |
| US11413356B2 (en) | 2016-04-15 | 2022-08-16 | University Of Massachusetts | Methods and compositions for treating metabolic imbalance |
| WO2017191274A2 (en) * | 2016-05-04 | 2017-11-09 | Curevac Ag | Rna encoding a therapeutic protein |
| US10610606B2 (en) * | 2018-02-01 | 2020-04-07 | Homology Medicines, Inc. | Adeno-associated virus compositions for PAH gene transfer and methods of use thereof |
-
2021
- 2021-04-22 EP EP21795587.1A patent/EP4142759A4/en active Pending
- 2021-04-22 CA CA3174070A patent/CA3174070A1/en active Pending
- 2021-04-22 JP JP2022566010A patent/JP7821742B2/ja active Active
- 2021-04-22 BR BR112022021964A patent/BR112022021964A2/pt unknown
- 2021-04-22 AU AU2021263534A patent/AU2021263534A1/en active Pending
- 2021-04-22 US US17/997,312 patent/US20230165977A1/en active Pending
- 2021-04-22 CN CN202180031917.6A patent/CN115461066B/zh active Active
- 2021-04-22 KR KR1020227041079A patent/KR20230003012A/ko active Pending
- 2021-04-22 WO PCT/US2021/028658 patent/WO2021221995A1/en not_active Ceased
- 2021-04-22 IL IL297605A patent/IL297605A/en unknown
- 2021-04-28 TW TW110115439A patent/TW202206599A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023524024A5 (https=) | ||
| CN115298316B (zh) | 用于制备腺相关病毒载体的方法 | |
| JP2024009857A5 (https=) | ||
| RU2021102893A (ru) | Модифицированные гены атаксии фридрейха и векторы для генной терапии | |
| JP6174318B2 (ja) | アデノ随伴ウイルス構築物を含んでなるコンダクティング気道細胞を標的とするための組成物 | |
| JP2022508182A5 (https=) | ||
| JP2021019591A5 (https=) | ||
| JP2021106619A5 (https=) | ||
| ES2277829T3 (es) | Composiciones y metodos para la produccion libre de adyuvante de virus adenoasociados recombinantes. | |
| US6509150B1 (en) | Compositions and methods for recombinant Adeno-Associated Virus production | |
| US20040052764A1 (en) | Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids | |
| KR20190032375A (ko) | 신규 아데노-관련 바이러스 캡시드 단백질 | |
| JP2018531609A5 (https=) | ||
| MX2011010116A (es) | Metodo de codificacion de video, metodo de decodificacion de video, aparato de codificacion de video y aparato de decodificacion de video. | |
| US20240318199A1 (en) | Adeno-associated virus (aav) systems for treatment of progranulin associated neurodegenerative diseases or disorders | |
| US20240067678A1 (en) | Adeno-associated virus capsids and vectors | |
| JP2023537358A5 (https=) | ||
| JP2023513892A (ja) | Ｄｎａ増幅方法 | |
| JP2023541443A5 (https=) | ||
| CN116419974A (zh) | 重组aav的制备方法 | |
| US20220242917A1 (en) | Compositions and methods for producing adeno-associated viral vectors | |
| CA3122319A1 (en) | Expression cassettes for gene therapy vectors | |
| JP2025535062A (ja) | 二重トランスフェクションベクター | |
| CN119569834A (zh) | 靶向心肌细胞的aav衣壳蛋白变体及其用途 | |
| KR102874560B1 (ko) | 아데노연관바이러스 변이체 |