CN114761569A - 阿尔茨海默氏病的基因疗法 - Google Patents

阿尔茨海默氏病的基因疗法 Download PDF

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CN114761569A
CN114761569A CN202080073402.8A CN202080073402A CN114761569A CN 114761569 A CN114761569 A CN 114761569A CN 202080073402 A CN202080073402 A CN 202080073402A CN 114761569 A CN114761569 A CN 114761569A
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vector
composition
sequence
sequences
nucleic acid
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R·G·克雷斯托
K·斯泰尔斯
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Cornell University
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • C12N2310/141—MicroRNAs, miRNAs
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CN202080073402.8A 2019-10-16 2020-10-16 阿尔茨海默氏病的基因疗法 Pending CN114761569A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962915988P 2019-10-16 2019-10-16
US62/915,988 2019-10-16
PCT/US2020/056051 WO2021076941A1 (en) 2019-10-16 2020-10-16 Gene therapy for alzheimer's disease

Publications (1)

Publication Number Publication Date
CN114761569A true CN114761569A (zh) 2022-07-15

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US (1) US20230405148A1 (https=)
EP (1) EP4045653A1 (https=)
JP (2) JP2023500793A (https=)
KR (1) KR20220082050A (https=)
CN (1) CN114761569A (https=)
AU (2) AU2020367437B2 (https=)
BR (1) BR112022007010A2 (https=)
CA (1) CA3157864A1 (https=)
CO (1) CO2022006367A2 (https=)
IL (1) IL292148A (https=)
MX (1) MX2022004524A (https=)
WO (1) WO2021076941A1 (https=)
ZA (1) ZA202205344B (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
US12611467B2 (en) 2020-11-25 2026-04-28 Cornell University APOE gene therapy

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JP7616995B2 (ja) * 2018-11-28 2025-01-17 プリベイル セラピューティクス，インコーポレーテッド 神経変性疾患のための遺伝子治療
EP4508213A1 (en) * 2022-04-12 2025-02-19 uniQure biopharma B.V. Nucleic acid regulation of apoe
EP4551711A1 (en) * 2022-07-08 2025-05-14 Cornell University Methods and pharmaceutical compositions for the treatment and the prevention of alzheimers disease
WO2025213111A2 (en) * 2024-04-05 2025-10-09 Cornell University Aav expression of mirna to suppress human apoe mrna

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WO2013181618A2 (en) * 2012-05-31 2013-12-05 The Trustees Of Columbia University In The City Of New York Methods to treat alzheimer's disease using apoe inhibitors
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12611467B2 (en) 2020-11-25 2026-04-28 Cornell University APOE gene therapy

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US20230405148A1 (en) 2023-12-21
CA3157864A1 (en) 2021-04-22
JP2026041903A (ja) 2026-03-10
JP2023500793A (ja) 2023-01-11
WO2021076941A1 (en) 2021-04-22
ZA202205344B (en) 2023-03-29
AU2020367437B2 (en) 2024-11-07
BR112022007010A2 (pt) 2022-07-12
AU2025200812A1 (en) 2025-02-27
MX2022004524A (es) 2022-07-21
EP4045653A1 (en) 2022-08-24
WO2021076941A9 (en) 2021-10-07
KR20220082050A (ko) 2022-06-16
IL292148A (en) 2022-06-01
AU2020367437A1 (en) 2022-06-02
CO2022006367A2 (es) 2022-08-09

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