JP2025513066A5 - - Google Patents
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- Publication number
- JP2025513066A5 JP2025513066A5 JP2024560442A JP2024560442A JP2025513066A5 JP 2025513066 A5 JP2025513066 A5 JP 2025513066A5 JP 2024560442 A JP2024560442 A JP 2024560442A JP 2024560442 A JP2024560442 A JP 2024560442A JP 2025513066 A5 JP2025513066 A5 JP 2025513066A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22167926.9 | 2022-04-12 | ||
| EP22167926 | 2022-04-12 | ||
| EP22200272.7 | 2022-10-07 | ||
| EP22200272 | 2022-10-07 | ||
| EP23162681 | 2023-03-17 | ||
| EP23162681.3 | 2023-03-17 | ||
| PCT/EP2023/059507 WO2023198745A1 (en) | 2022-04-12 | 2023-04-12 | Nucleic acid regulation of apoe |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025513066A JP2025513066A (ja) | 2025-04-22 |
| JP2025513066A5 true JP2025513066A5 (https=) | 2026-04-20 |
| JPWO2023198745A5 JPWO2023198745A5 (https=) | 2026-04-20 |
Family
ID=85873819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024560442A Pending JP2025513066A (ja) | 2022-04-12 | 2023-04-12 | Apoeの核酸制御 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250223590A1 (https=) |
| EP (1) | EP4508213A1 (https=) |
| JP (1) | JP2025513066A (https=) |
| CN (1) | CN119032174A (https=) |
| WO (1) | WO2023198745A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025090631A1 (en) * | 2023-10-23 | 2025-05-01 | The Children's Hospital Of Philadelphia | Aav vectors for delivery of apoe2 |
| WO2025213111A2 (en) * | 2024-04-05 | 2025-10-09 | Cornell University | Aav expression of mirna to suppress human apoe mrna |
| WO2025219443A1 (en) * | 2024-04-19 | 2025-10-23 | Uniqure Biopharma B.V. | Nucleic acid for a1at regulation |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6103526A (en) | 1998-10-08 | 2000-08-15 | Protein Sciences Corporation | Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using |
| EP2311967B1 (en) | 2005-10-20 | 2017-09-20 | UniQure IP B.V. | Improved AAV vectors produced in insect cells |
| KR101589259B1 (ko) | 2006-06-21 | 2016-02-01 | 유니큐어 아이피 비.브이. | 곤충세포 내 aav의 생산에 유용한 aav-rep78의 번역을 위한 변형된 개시 코돈을 갖는 벡터 |
| SI3093345T1 (sl) | 2007-07-26 | 2019-08-30 | Uniqure Ip B.V. | Bakulovirusni vektorji, ki vsebujejo ponavljajoča kodirna zaporedja z različnimi kodonskimi preferencami |
| EP3257937B1 (en) | 2008-02-19 | 2022-08-03 | uniQure IP B.V. | Optimisation of expression of parvoviral rep and cap proteins in insect cells |
| WO2011122950A1 (en) | 2010-04-01 | 2011-10-06 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Monomeric duplex aav vectors |
| PT2744895E (pt) | 2011-09-08 | 2016-02-08 | Uniqure Ip Bv | Remoção de vírus contaminantes de preparações de aav |
| WO2015137802A1 (en) | 2014-03-10 | 2015-09-17 | Uniqure Ip B.V. | Further improved aav vectors produced in insect cells |
| AU2015370903B2 (en) * | 2014-12-24 | 2021-06-17 | Uniqure Ip B.V. | RNAi induced huntingtin gene suppression |
| JP7666922B2 (ja) | 2017-07-20 | 2025-04-22 | ユニキュアー アイピー ビー.ブイ. | 昆虫細胞における向上したaavカプシド産生 |
| EP4045653A1 (en) * | 2019-10-16 | 2022-08-24 | Cornell University | Gene therapy for alzheimer's disease |
| EP4065600A1 (en) * | 2019-11-25 | 2022-10-05 | Cornell University | Apoe gene therapy |
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2023
- 2023-04-12 EP EP23715186.5A patent/EP4508213A1/en active Pending
- 2023-04-12 WO PCT/EP2023/059507 patent/WO2023198745A1/en not_active Ceased
- 2023-04-12 US US18/851,078 patent/US20250223590A1/en active Pending
- 2023-04-12 JP JP2024560442A patent/JP2025513066A/ja active Pending
- 2023-04-12 CN CN202380033802.XA patent/CN119032174A/zh active Pending