JP2022511453A5 - - Google Patents

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Publication number
JP2022511453A5
JP2022511453A5 JP2021530800A JP2021530800A JP2022511453A5 JP 2022511453 A5 JP2022511453 A5 JP 2022511453A5 JP 2021530800 A JP2021530800 A JP 2021530800A JP 2021530800 A JP2021530800 A JP 2021530800A JP 2022511453 A5 JP2022511453 A5 JP 2022511453A5
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JP
Japan
Application number
JP2021530800A
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Japanese (ja)
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JP7616995B2 (ja
JPWO2020112802A5 (https=
JP2022511453A (ja
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Priority claimed from PCT/US2019/063289 external-priority patent/WO2020112802A1/en
Publication of JP2022511453A publication Critical patent/JP2022511453A/ja
Publication of JP2022511453A5 publication Critical patent/JP2022511453A5/ja
Publication of JPWO2020112802A5 publication Critical patent/JPWO2020112802A5/ja
Priority to JP2024128634A priority Critical patent/JP2024177670A/ja
Application granted granted Critical
Publication of JP7616995B2 publication Critical patent/JP7616995B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021530800A 2018-11-28 2019-11-26 神経変性疾患のための遺伝子治療 Active JP7616995B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024128634A JP2024177670A (ja) 2018-11-28 2024-08-05 神経変性疾患のための遺伝子治療

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862772230P 2018-11-28 2018-11-28
US62/772,230 2018-11-28
PCT/US2019/063289 WO2020112802A1 (en) 2018-11-28 2019-11-26 Gene therapies for neurodegenerative disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024128634A Division JP2024177670A (ja) 2018-11-28 2024-08-05 神経変性疾患のための遺伝子治療

Publications (4)

Publication Number Publication Date
JP2022511453A JP2022511453A (ja) 2022-01-31
JP2022511453A5 true JP2022511453A5 (https=) 2022-11-21
JPWO2020112802A5 JPWO2020112802A5 (https=) 2022-11-21
JP7616995B2 JP7616995B2 (ja) 2025-01-17

Family

ID=70852200

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021530800A Active JP7616995B2 (ja) 2018-11-28 2019-11-26 神経変性疾患のための遺伝子治療
JP2024128634A Withdrawn JP2024177670A (ja) 2018-11-28 2024-08-05 神経変性疾患のための遺伝子治療

Family Applications After (1)

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JP2024128634A Withdrawn JP2024177670A (ja) 2018-11-28 2024-08-05 神経変性疾患のための遺伝子治療

Country Status (11)

Country Link
US (1) US20220010001A1 (https=)
EP (1) EP3887396A4 (https=)
JP (2) JP7616995B2 (https=)
KR (1) KR20210096168A (https=)
CN (1) CN113557243A (https=)
AU (1) AU2019388975A1 (https=)
BR (1) BR112021010234A2 (https=)
CA (1) CA3121211A1 (https=)
IL (1) IL283496B2 (https=)
MX (1) MX2021006253A (https=)
WO (1) WO2020112802A1 (https=)

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Publication number Priority date Publication date Assignee Title
BR112020006671A2 (pt) 2017-10-03 2020-12-01 Prevail Therapeutics, Inc. terapias genéticas para distúrbios lisossômicos
KR102709597B1 (ko) 2017-10-03 2024-09-26 프리베일 테라퓨틱스, 인크. 리소좀 장애를 위한 유전자 요법
EP4045653A1 (en) * 2019-10-16 2022-08-24 Cornell University Gene therapy for alzheimer's disease
EP4232572A4 (en) * 2020-10-22 2024-09-25 Duke University COMPOSITIONS AND PROCEDURES RELATED TO ALZHEIMER’S DISEASE
KR20230112672A (ko) * 2020-11-25 2023-07-27 프리베일 테라퓨틱스, 인크. 신경변성 질환을 위한 유전자 요법
EP4426833A1 (en) * 2021-11-03 2024-09-11 F. Hoffmann-La Roche AG Oligonucleotides for modulating apolipoprotein e4 expression
EP4615981A1 (en) 2022-11-11 2025-09-17 Eli Lilly and Company Synthetic nucleic acids including astrocyte-directed promoter constructs and methods of using the same
CN119220609B (zh) * 2024-09-27 2025-09-12 科辉智药(深圳)新药研究中心有限公司 一种共表达TRIM11和ApoE2的核酸序列构建体及其应用

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Publication number Priority date Publication date Assignee Title
JP3265577B2 (ja) * 1992-10-13 2002-03-11 デューク・ユニバーシティ アポリポ蛋白eの4型イソ型の測定法
AU2001253233B2 (en) * 2000-04-06 2006-12-07 Kos Pharmaceuticals, Inc. Compounds and methods for lowering cholesterol levels without inducing hypertriglyceridemia
US20050019927A1 (en) * 2003-07-13 2005-01-27 Markus Hildinger DECREASING GENE EXPRESSION IN A MAMMALIAN SUBJECT IN VIVO VIA AAV-MEDIATED RNAi EXPRESSION CASSETTE TRANSFER
US8435539B2 (en) * 2004-02-13 2013-05-07 Immunomedics, Inc. Delivery system for cytotoxic drugs by bispecific antibody pretargeting
CA2643048A1 (en) * 2006-02-21 2007-08-30 Oklahoma Medical Research Foundation Treatment of alzheimer's disease with inhibitors of apoe binding to apoe receptor
JP6469000B2 (ja) * 2012-05-18 2019-02-13 ユニバーシティー オブ アイオワ リサーチ ファウンデーション アミロイドの沈着を処置するための方法および組成物
WO2013181618A2 (en) * 2012-05-31 2013-12-05 The Trustees Of Columbia University In The City Of New York Methods to treat alzheimer's disease using apoe inhibitors
EP3626309B1 (en) * 2012-08-13 2023-03-08 The Rockefeller University Lxrbeta agonist for the treatment of cancer
MX2016006584A (es) * 2013-11-20 2016-09-06 Univ Iowa Res Found Métodos y composiciones para tratar los depósitos de amiloide.
WO2015153760A2 (en) * 2014-04-01 2015-10-08 Sangamo Biosciences, Inc. Methods and compositions for prevention or treatment of a nervous system disorder
EP3842514A1 (en) * 2014-09-12 2021-06-30 Whitehead Institute for Biomedical Research Cells expressing apolipoprotein e and uses thereof
WO2018045347A1 (en) * 2016-09-02 2018-03-08 Spark Therapeutics, Inc. Methods and vectors for treating cns disorders
KR102719222B1 (ko) * 2017-05-11 2024-10-21 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 신경 세로이드 지질갈색소증에 대한 유전자 요법
EP4045653A1 (en) * 2019-10-16 2022-08-24 Cornell University Gene therapy for alzheimer's disease

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