JP2023524291A5 - - Google Patents
Info
- Publication number
- JP2023524291A5 JP2023524291A5 JP2022567079A JP2022567079A JP2023524291A5 JP 2023524291 A5 JP2023524291 A5 JP 2023524291A5 JP 2022567079 A JP2022567079 A JP 2022567079A JP 2022567079 A JP2022567079 A JP 2022567079A JP 2023524291 A5 JP2023524291 A5 JP 2023524291A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- item
- vector
- vector according
- capsid protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020062P | 2020-05-05 | 2020-05-05 | |
| US63/020,062 | 2020-05-05 | ||
| PCT/US2021/030937 WO2021226267A2 (en) | 2020-05-05 | 2021-05-05 | Cross-species compatible adeno-associated virus compositions and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524291A JP2023524291A (ja) | 2023-06-09 |
| JP2023524291A5 true JP2023524291A5 (https=) | 2024-05-15 |
| JP7756439B2 JP7756439B2 (ja) | 2025-10-20 |
Family
ID=78468375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567079A Active JP7756439B2 (ja) | 2020-05-05 | 2021-05-05 | 異種間適合性アデノ随伴ウイルス組成物およびその使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US12577586B2 (https=) |
| EP (1) | EP4125977A4 (https=) |
| JP (1) | JP7756439B2 (https=) |
| KR (1) | KR20230029616A (https=) |
| CN (1) | CN116096377B (https=) |
| AR (1) | AR122013A1 (https=) |
| AU (1) | AU2021268946A1 (https=) |
| BR (1) | BR112022022644A2 (https=) |
| CA (1) | CA3177869A1 (https=) |
| IL (1) | IL297577A (https=) |
| MX (1) | MX2022013963A (https=) |
| TW (1) | TWI910162B (https=) |
| WO (1) | WO2021226267A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3177869A1 (en) * | 2020-05-05 | 2021-11-11 | Duke University | Cross-species compatible adeno-associated virus compositions and methods of use thereof |
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| US20260055144A1 (en) * | 2022-08-24 | 2026-02-26 | Regenxbio Inc. | Recombinant adeno-associated viruses and uses thereof |
| WO2024168089A2 (en) * | 2023-02-07 | 2024-08-15 | Duke University | Compositions comprising aavs and methods for treating gastrointestinal diseases |
| EP4661916A1 (en) * | 2023-02-08 | 2025-12-17 | Ginkgo Bioworks, Inc. | Gene therapy for angelman syndrome |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| AU2024242227A1 (en) * | 2023-03-31 | 2025-11-13 | Duke University | Compositions comprising brain-tropic aavs and methods of use thereof |
| AU2024332181A1 (en) | 2023-08-31 | 2026-02-12 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2025250454A1 (en) * | 2024-05-28 | 2025-12-04 | University Of Rochester | Adeno-associated viruses evolved to specifically target human glial progenitor cells in vivo |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| AU780231B2 (en) | 1998-11-10 | 2005-03-10 | University Of North Carolina At Chapel Hill, The | Virus vectors and methods of making and administering the same |
| US7314912B1 (en) | 1999-06-21 | 2008-01-01 | Medigene Aktiengesellschaft | AAv scleroprotein, production and use thereof |
| ATE318923T1 (de) | 2000-06-01 | 2006-03-15 | Univ North Carolina | Doppelsträngige parvovirus-vektoren |
| EP2345731B1 (en) * | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| EP2018421B1 (en) * | 2006-04-28 | 2012-12-19 | The Trustees of the University of Pennsylvania | Scalable production method for aav |
| US8734809B2 (en) | 2009-05-28 | 2014-05-27 | University Of Massachusetts | AAV's and uses thereof |
| WO2012109570A1 (en) | 2011-02-10 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| WO2013170078A1 (en) | 2012-05-09 | 2013-11-14 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| EP3003391B1 (en) | 2013-05-31 | 2021-09-22 | The Regents of The University of California | Adeno-associated virus variants and methods of use thereof |
| WO2015164757A1 (en) | 2014-04-25 | 2015-10-29 | Oregon Health & Science University | Methods of viral neutralizing antibody epitope mapping |
| EP3151866B1 (en) * | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| ES2865487T3 (es) | 2015-09-28 | 2021-10-15 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores virales que evaden los anticuerpos |
| US11905312B2 (en) | 2017-02-15 | 2024-02-20 | The University Of North Carolina At Chapel Hill | Methods and compositions for gene transfer across the vasculature |
| JP2020510424A (ja) * | 2017-02-28 | 2020-04-09 | アドヴェラム バイオテクノロジーズ， インコーポレイテッド | 改変ａａｖカプシドおよびその使用 |
| WO2018170015A1 (en) | 2017-03-14 | 2018-09-20 | The Regents Of The University Of California | Engineering crispr cas9 immune stealth |
| US10550405B2 (en) | 2017-03-15 | 2020-02-04 | The University Of North Carolina At Chapel Hill | Rational polyploid adeno-associated virus vectors and methods of making and using the same |
| NZ756587A (en) * | 2017-03-15 | 2025-12-19 | Univ North Carolina Chapel Hill | Polyploid adeno-associated virus vectors and methods of making and using the same |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| MX2020010465A (es) | 2018-04-03 | 2021-01-08 | Vectores de virus para direccionamiento a tejidos oftalmicos. | |
| EP3774852A1 (en) | 2018-04-03 | 2021-02-17 | Stridebio, Inc. | Antibody-evading virus vectors |
| US20210214749A1 (en) | 2018-05-16 | 2021-07-15 | Voyager Therapeutics, Inc. | Directed evolution |
| CA3114175A1 (en) * | 2018-10-01 | 2020-04-09 | The Trustees Of The University Of Pennsylvania | Beta-galactosidase based aav for treating gm1 gangliosidosis |
| AR118465A1 (es) | 2019-03-21 | 2021-10-06 | Stridebio Inc | Vectores de virus adenoasociados recombinantes |
| CA3177869A1 (en) | 2020-05-05 | 2021-11-11 | Duke University | Cross-species compatible adeno-associated virus compositions and methods of use thereof |
-
2021
- 2021-05-05 CA CA3177869A patent/CA3177869A1/en active Pending
- 2021-05-05 BR BR112022022644A patent/BR112022022644A2/pt unknown
- 2021-05-05 CN CN202180044147.9A patent/CN116096377B/zh active Active
- 2021-05-05 JP JP2022567079A patent/JP7756439B2/ja active Active
- 2021-05-05 KR KR1020227042650A patent/KR20230029616A/ko active Pending
- 2021-05-05 US US17/922,962 patent/US12577586B2/en active Active
- 2021-05-05 TW TW110116293A patent/TWI910162B/zh active
- 2021-05-05 EP EP21800135.2A patent/EP4125977A4/en active Pending
- 2021-05-05 AR ARP210101222A patent/AR122013A1/es not_active Application Discontinuation
- 2021-05-05 AU AU2021268946A patent/AU2021268946A1/en active Pending
- 2021-05-05 WO PCT/US2021/030937 patent/WO2021226267A2/en not_active Ceased
- 2021-05-05 IL IL297577A patent/IL297577A/en unknown
- 2021-05-05 MX MX2022013963A patent/MX2022013963A/es unknown
-
2023
- 2023-09-26 US US18/474,506 patent/US12146151B2/en active Active
- 2023-09-26 US US18/474,533 patent/US12037598B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023524291A5 (https=) | ||
| JP7707261B2 (ja) | 筋疾患の治療のための改変ａａｖカプシドポリペプチド | |
| JP2022530633A5 (https=) | ||
| JP2022526018A5 (https=) | ||
| JP2022530656A5 (https=) | ||
| JP2022530544A5 (https=) | ||
| AU2017235333A1 (en) | CRISPR/CAS-related methods and compositions for treating beta hemoglobinopathies | |
| WO2004020600A2 (en) | Modified aav | |
| RU2751592C2 (ru) | Выделенный модифицированный белок VP1 капсида аденоассоциированного вируса 5 серотипа (AAV5), капсид и вектор на его основе | |
| US12359219B2 (en) | Transgene cassettes designed to express a human MECP2 gene | |
| JP2022530824A5 (https=) | ||
| TW201629225A (zh) | 第九因子基因療法 | |
| JP2022531861A5 (https=) | ||
| JP2022501060A5 (https=) | ||
| US20220380798A1 (en) | AAV Expression Cassette and AAV Vectors Comprising the Same | |
| JP2021531044A5 (https=) | ||
| JP2021500070A5 (https=) | ||
| CN121219423A (zh) | 工程化血脑屏障穿透型aav衣壳 | |
| JP2025513066A5 (https=) | ||
| CN119403823A (zh) | 具有增强的肌肉转导效率的肽修饰的aav衣壳 | |
| CA3271456A1 (en) | AAVS RECOMMENDATIONS WITH IMPROVED TROPISM AND SPECIFICITY | |
| JP2022525848A5 (https=) | ||
| JP2024515902A5 (https=) | ||
| EP4380626A1 (en) | Adeno-associated virus particles and methods of use thereof | |
| WO2021230385A1 (en) | Method for treating muscular dystrophy by targeting utrophin gene |