JP2023030130A5 - - Google Patents
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- JP2023030130A5 JP2023030130A5 JP2022206897A JP2022206897A JP2023030130A5 JP 2023030130 A5 JP2023030130 A5 JP 2023030130A5 JP 2022206897 A JP2022206897 A JP 2022206897A JP 2022206897 A JP2022206897 A JP 2022206897A JP 2023030130 A5 JP2023030130 A5 JP 2023030130A5
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- JP
- Japan
- Prior art keywords
- vitamin
- composition
- administered
- producing
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims 10
- 235000013305 food Nutrition 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 229930003761 Vitamin B9 Natural products 0.000 claims 5
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 5
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims 5
- 235000019158 vitamin B6 Nutrition 0.000 claims 5
- 239000011726 vitamin B6 Substances 0.000 claims 5
- 235000019159 vitamin B9 Nutrition 0.000 claims 5
- 239000011727 vitamin B9 Substances 0.000 claims 5
- 229940011671 vitamin b6 Drugs 0.000 claims 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 3
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims 3
- 229930003451 Vitamin B1 Natural products 0.000 claims 3
- 229930003471 Vitamin B2 Natural products 0.000 claims 3
- 229930003537 Vitamin B3 Natural products 0.000 claims 3
- 229930003571 Vitamin B5 Natural products 0.000 claims 3
- 229930003756 Vitamin B7 Natural products 0.000 claims 3
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims 3
- 229960002079 calcium pantothenate Drugs 0.000 claims 3
- 229960003512 nicotinic acid Drugs 0.000 claims 3
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 3
- 229960002477 riboflavin Drugs 0.000 claims 3
- 229960003495 thiamine Drugs 0.000 claims 3
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims 3
- 235000010374 vitamin B1 Nutrition 0.000 claims 3
- 239000011691 vitamin B1 Substances 0.000 claims 3
- 235000019164 vitamin B2 Nutrition 0.000 claims 3
- 239000011716 vitamin B2 Substances 0.000 claims 3
- 235000019160 vitamin B3 Nutrition 0.000 claims 3
- 239000011708 vitamin B3 Substances 0.000 claims 3
- 239000011675 vitamin B5 Substances 0.000 claims 3
- 235000009492 vitamin B5 Nutrition 0.000 claims 3
- 235000011912 vitamin B7 Nutrition 0.000 claims 3
- 239000011735 vitamin B7 Substances 0.000 claims 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 2
- 229930003779 Vitamin B12 Natural products 0.000 claims 2
- 229930003268 Vitamin C Natural products 0.000 claims 2
- 229930003316 Vitamin D Natural products 0.000 claims 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 2
- 229930003427 Vitamin E Natural products 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims 2
- 229960001231 choline Drugs 0.000 claims 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 2
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 2
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 2
- 229940088594 vitamin Drugs 0.000 claims 2
- 229930003231 vitamin Natural products 0.000 claims 2
- 235000013343 vitamin Nutrition 0.000 claims 2
- 239000011782 vitamin Substances 0.000 claims 2
- 235000019163 vitamin B12 Nutrition 0.000 claims 2
- 239000011715 vitamin B12 Substances 0.000 claims 2
- 235000019154 vitamin C Nutrition 0.000 claims 2
- 239000011718 vitamin C Substances 0.000 claims 2
- 235000019166 vitamin D Nutrition 0.000 claims 2
- 239000011710 vitamin D Substances 0.000 claims 2
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 2
- 235000019165 vitamin E Nutrition 0.000 claims 2
- 239000011709 vitamin E Substances 0.000 claims 2
- 229940046009 vitamin E Drugs 0.000 claims 2
- 229940046008 vitamin d Drugs 0.000 claims 2
- 206010012289 Dementia Diseases 0.000 claims 1
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 claims 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 229960002173 citrulline Drugs 0.000 claims 1
- 235000013477 citrulline Nutrition 0.000 claims 1
- 230000001149 cognitive effect Effects 0.000 claims 1
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- 235000019197 fats Nutrition 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000006014 omega-3 oil Substances 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Images
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762484119P | 2017-04-11 | 2017-04-11 | |
| US201762484156P | 2017-04-11 | 2017-04-11 | |
| US62/484,119 | 2017-04-11 | ||
| US62/484,156 | 2017-04-11 | ||
| EP17193916.8 | 2017-09-29 | ||
| EPPCT/EP2017/074731 | 2017-09-29 | ||
| PCT/EP2017/074731 WO2018060396A1 (en) | 2016-09-29 | 2017-09-29 | Omega 3 fatty acids and choline as neuroprotectant in patients with no dementia |
| EP17193916.8A EP3388061A1 (en) | 2017-04-11 | 2017-09-29 | Omega 3 fatty acids, no releasing compound, vitamin b12 and choline as neuroprotectant in patients with no dementia |
| US201762580574P | 2017-11-02 | 2017-11-02 | |
| US62/580,574 | 2017-11-02 | ||
| PCT/EP2017/082148 WO2018188771A1 (en) | 2017-04-11 | 2017-12-11 | Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals |
| EPPCT/EP2017/082148 | 2017-12-11 | ||
| JP2019550713A JP2020516586A (ja) | 2017-04-11 | 2018-04-05 | 認知症ではない個体において、認知的加齢を軽減する組成物及び方法 |
| PCT/EP2018/058710 WO2018189022A1 (en) | 2017-04-11 | 2018-04-05 | Compositions and methods that attenuate cognitive aging in individuals who do not have dementia |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550713A Division JP2020516586A (ja) | 2017-04-11 | 2018-04-05 | 認知症ではない個体において、認知的加齢を軽減する組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023030130A JP2023030130A (ja) | 2023-03-07 |
| JP2023030130A5 true JP2023030130A5 (enExample) | 2024-04-04 |
| JP7524294B2 JP7524294B2 (ja) | 2024-07-29 |
Family
ID=67682482
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550821A Active JP7270546B2 (ja) | 2017-04-11 | 2017-12-11 | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
| JP2019550713A Pending JP2020516586A (ja) | 2017-04-11 | 2018-04-05 | 認知症ではない個体において、認知的加齢を軽減する組成物及び方法 |
| JP2019551444A Active JP7270547B2 (ja) | 2017-04-11 | 2018-04-05 | 個体における認知的加齢を特定及び軽減するためのオメガ－３脂肪酸、ホモシステイン及びビタミンｄのレベル。 |
| JP2022129344A Active JP7434458B2 (ja) | 2017-04-11 | 2022-08-15 | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
| JP2022129345A Active JP7434459B2 (ja) | 2017-04-11 | 2022-08-15 | 個体における認知的加齢を特定及び軽減するためのオメガ－３脂肪酸、ホモシステイン及びビタミンｄのレベル |
| JP2022206897A Active JP7524294B2 (ja) | 2017-04-11 | 2022-12-23 | 認知症ではない個体において認知的加齢を軽減する組成物の製造方法 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550821A Active JP7270546B2 (ja) | 2017-04-11 | 2017-12-11 | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
| JP2019550713A Pending JP2020516586A (ja) | 2017-04-11 | 2018-04-05 | 認知症ではない個体において、認知的加齢を軽減する組成物及び方法 |
| JP2019551444A Active JP7270547B2 (ja) | 2017-04-11 | 2018-04-05 | 個体における認知的加齢を特定及び軽減するためのオメガ－３脂肪酸、ホモシステイン及びビタミンｄのレベル。 |
| JP2022129344A Active JP7434458B2 (ja) | 2017-04-11 | 2022-08-15 | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
| JP2022129345A Active JP7434459B2 (ja) | 2017-04-11 | 2022-08-15 | 個体における認知的加齢を特定及び軽減するためのオメガ－３脂肪酸、ホモシステイン及びビタミンｄのレベル |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US20210128587A1 (enExample) |
| EP (3) | EP3609490A1 (enExample) |
| JP (6) | JP7270546B2 (enExample) |
| CN (3) | CN110381935A (enExample) |
| AU (5) | AU2017408873A1 (enExample) |
| BR (3) | BR112019017949A2 (enExample) |
| CA (3) | CA3054846A1 (enExample) |
| MX (2) | MX2019010484A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7270546B2 (ja) * | 2017-04-11 | 2023-05-10 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
| CN113252806B (zh) * | 2021-03-25 | 2023-08-29 | 嘉兴学院 | S-腺苷同型半胱氨酸在制备用于诊断或治疗川崎病的产品中的用途 |
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| US6153653A (en) * | 1997-11-26 | 2000-11-28 | Protarga, Inc. | Choline compositions and uses thereof |
| US20070004670A1 (en) * | 1998-07-31 | 2007-01-04 | Richard Wurtman | Compositions containing citicoline, and methods of use thereof |
| GB0016460D0 (en) * | 2000-07-04 | 2000-08-23 | Axis Shield Asa | Assay |
| US6964969B2 (en) * | 2001-04-19 | 2005-11-15 | Mccleary Edward Larry | Composition and method for treating impaired or deteriorating neurological function |
| US8017657B1 (en) * | 2001-09-07 | 2011-09-13 | Advanced Medical Instruments | Composition for the treatment and prevention of endothelial dysfunction |
| WO2004075905A1 (ja) * | 2003-02-26 | 2004-09-10 | Kyowa Hakko Kogyo Co., Ltd. | 筋肉増強剤および筋肉減衰の予防または治療剤 |
| US20070078114A1 (en) * | 2005-09-02 | 2007-04-05 | Myriad Genetics, Incorporated | Combination therapy for alzheimer's disease and other diseases |
| US20080003330A1 (en) * | 2006-06-30 | 2008-01-03 | Ricardo Rueda | Infant formulas for early brain development |
| NZ582329A (en) | 2007-06-26 | 2012-09-28 | Nutricia Nv | Improving memory in subjects with mini-mental state examination of 24-26 |
| WO2009002148A1 (en) * | 2007-06-27 | 2008-12-31 | N.V. Nutricia | Food composition for prodromal dementia patients |
| AU2008307494B2 (en) * | 2007-10-04 | 2013-09-05 | Société des Produits Nestlé S.A. | Compositions and methods for enhancing cognitive function |
| CN101909632A (zh) * | 2008-01-04 | 2010-12-08 | 雀巢产品技术援助有限公司 | 包含不饱和脂肪酸和一氧化氮释放化合物的组合物及其用于增强认知和相关功能的用途 |
| NZ735173A (en) | 2008-12-09 | 2022-10-28 | Stephanie Fryar Williams | Biomarkers for the diagnosis and/or prediction of susceptibility to mental and neurodegenerative disorders |
| US8933255B2 (en) * | 2008-12-31 | 2015-01-13 | Nitromega Corp. | Nutraceuticals containing nitro fatty acids |
| CN101897706A (zh) * | 2009-05-27 | 2010-12-01 | 北京奥萨医药研究中心有限公司 | 含有叶酸和b族维生素的组合物及其用途 |
| US20120148685A1 (en) * | 2009-06-10 | 2012-06-14 | Engergy4Life AG | Methods and compositions for treating insulin resistance, diabetes mellitus type 2, metabolic syndrome and related disorders |
| US8563609B2 (en) * | 2010-05-13 | 2013-10-22 | Nitromega Corp. | Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline |
| AU2011315537A1 (en) | 2010-10-12 | 2013-05-02 | Vifor Sa | Novel omega-3 and omega-6 fatty acid compositions and uses thereof |
| ES2727043T3 (es) * | 2011-03-18 | 2019-10-11 | Nestle Sa | Composiciones y métodos útiles para mejorar enfermedades relacionadas con la edad |
| EP2773339A1 (en) * | 2011-10-31 | 2014-09-10 | N.V. Nutricia | Composition for improving neuropsychological test battery score |
| EP2882304A1 (en) * | 2012-08-07 | 2015-06-17 | Buck Institute For Research On Aging | Multi-component formulation for improving neurological function |
| FR3002044A1 (fr) * | 2013-02-08 | 2014-08-15 | Centre Nat Rech Scient | Marqueur dyrk1a pour la maladie d'alzheimer |
| US20140271844A1 (en) * | 2013-03-15 | 2014-09-18 | Nitromega Corp. | Compositions containing nitro fatty acids |
| AU2014235034A1 (en) | 2013-03-15 | 2015-10-01 | Buck Institute For Research On Aging | Improved cognitive supplements |
| EP2899543A1 (en) | 2014-01-28 | 2015-07-29 | Predemtec GmbH | Biomarker and methods for early diagnosis of Alzheimer's disease |
| GB201405033D0 (en) * | 2014-03-20 | 2014-05-07 | Isis Innovation | Combination therapy |
| ES2860427T3 (es) * | 2015-06-22 | 2021-10-05 | Nestle Sa | Composiciones y métodos para mejorar la neurogénesis en animales |
| WO2017004436A2 (en) * | 2015-07-01 | 2017-01-05 | The Regents Of The University Of California | A therapeutic system comprising pharmaceuticals in combination with metabolic enhancement for neurodegeneration |
| US20180268940A1 (en) * | 2015-09-25 | 2018-09-20 | Buck Institute For Research On Aging | Compositions and methods for specific biological cognitive functions in neurodegenerative diseases |
| JP2019518744A (ja) * | 2016-05-27 | 2019-07-04 | ネステク ソシエテ アノニム | 運動障害を治療又は予防するための栄養組成物 |
| EP3518919A1 (en) * | 2016-09-29 | 2019-08-07 | Société des Produits Nestlé S.A. | Omega 3 fatty acids and choline as neuroprotectant in patients with no dementia |
| JP7270546B2 (ja) | 2017-04-11 | 2023-05-10 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル |
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2017
- 2017-12-11 JP JP2019550821A patent/JP7270546B2/ja active Active
- 2017-12-11 BR BR112019017949A patent/BR112019017949A2/pt not_active Application Discontinuation
- 2017-12-11 CN CN201780087975.4A patent/CN110381935A/zh active Pending
- 2017-12-11 MX MX2019010484A patent/MX2019010484A/es unknown
- 2017-12-11 EP EP17816680.7A patent/EP3609490A1/en not_active Withdrawn
- 2017-12-11 AU AU2017408873A patent/AU2017408873A1/en not_active Abandoned
- 2017-12-11 US US16/603,749 patent/US20210128587A1/en not_active Abandoned
- 2017-12-11 CA CA3054846A patent/CA3054846A1/en active Pending
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2018
- 2018-04-05 EP EP18714287.2A patent/EP3609491B1/en active Active
- 2018-04-05 AU AU2018251094A patent/AU2018251094B2/en active Active
- 2018-04-05 AU AU2018251092A patent/AU2018251092B2/en active Active
- 2018-04-05 US US16/604,055 patent/US20200054665A1/en not_active Abandoned
- 2018-04-05 BR BR112019018729-4A patent/BR112019018729A2/pt not_active Application Discontinuation
- 2018-04-05 CN CN201880022932.2A patent/CN110475553A/zh active Pending
- 2018-04-05 CN CN201880018724.5A patent/CN110430873A/zh active Pending
- 2018-04-05 CA CA3054869A patent/CA3054869A1/en active Pending
- 2018-04-05 BR BR112019020008A patent/BR112019020008A2/pt unknown
- 2018-04-05 EP EP18714289.8A patent/EP3609487A1/en active Pending
- 2018-04-05 MX MX2019010828A patent/MX2019010828A/es unknown
- 2018-04-05 JP JP2019550713A patent/JP2020516586A/ja active Pending
- 2018-04-05 US US16/603,688 patent/US20210263048A1/en active Pending
- 2018-04-05 CA CA3054864A patent/CA3054864A1/en active Pending
- 2018-04-05 JP JP2019551444A patent/JP7270547B2/ja active Active
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2022
- 2022-08-15 JP JP2022129344A patent/JP7434458B2/ja active Active
- 2022-08-15 JP JP2022129345A patent/JP7434459B2/ja active Active
- 2022-10-06 US US17/960,966 patent/US20230028607A1/en not_active Abandoned
- 2022-12-23 JP JP2022206897A patent/JP7524294B2/ja active Active
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2023
- 2023-05-15 US US18/197,402 patent/US20230310488A1/en active Pending
- 2023-10-10 US US18/378,404 patent/US20240041915A1/en active Pending
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2024
- 2024-02-12 AU AU2024200882A patent/AU2024200882B9/en active Active
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2025
- 2025-08-19 AU AU2025220690A patent/AU2025220690A1/en active Pending
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