MX2019010484A - Niveles de acidos grasos omega-3 y vitamina d para identificar y atenuar el envejecimiento congnitivo en individuos. - Google Patents
Niveles de acidos grasos omega-3 y vitamina d para identificar y atenuar el envejecimiento congnitivo en individuos.Info
- Publication number
- MX2019010484A MX2019010484A MX2019010484A MX2019010484A MX2019010484A MX 2019010484 A MX2019010484 A MX 2019010484A MX 2019010484 A MX2019010484 A MX 2019010484A MX 2019010484 A MX2019010484 A MX 2019010484A MX 2019010484 A MX2019010484 A MX 2019010484A
- Authority
- MX
- Mexico
- Prior art keywords
- omega
- vitamin
- levels
- individuals
- identify
- Prior art date
Links
- 235000020660 omega-3 fatty acid Nutrition 0.000 title abstract 4
- 229940012843 omega-3 fatty acid Drugs 0.000 title abstract 4
- 229940046008 vitamin d Drugs 0.000 title abstract 4
- 230000032683 aging Effects 0.000 title 1
- 230000001149 cognitive effect Effects 0.000 title 1
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 title 1
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 abstract 3
- 229930003316 Vitamin D Natural products 0.000 abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 3
- 239000002207 metabolite Substances 0.000 abstract 3
- 239000006014 omega-3 oil Substances 0.000 abstract 3
- 235000019166 vitamin D Nutrition 0.000 abstract 3
- 239000011710 vitamin D Substances 0.000 abstract 3
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 3
- 230000006999 cognitive decline Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Feed For Specific Animals (AREA)
Abstract
Un método para identificar la predisposición al declive cognitivo en un sujeto, el método comprende determinar independientemente los niveles de: (a) ácidos grasos omega-3, y vitamina D o un metabolito de esta; (b) ácidos grasos omega-3, y homocisteína; (c) vitamina D o un metabolito de esta, y homocisteína; o (d) ácidos grasos omega-3, vitamina D o un metabolito de esta, y homocisteína, en una o más muestras obtenidas del sujeto.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762484119P | 2017-04-11 | 2017-04-11 | |
US201762484156P | 2017-04-11 | 2017-04-11 | |
EP17193916.8A EP3388061A1 (en) | 2017-04-11 | 2017-09-29 | Omega 3 fatty acids, no releasing compound, vitamin b12 and choline as neuroprotectant in patients with no dementia |
US201762580574P | 2017-11-02 | 2017-11-02 | |
PCT/EP2017/082148 WO2018188771A1 (en) | 2017-04-11 | 2017-12-11 | Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019010484A true MX2019010484A (es) | 2019-10-17 |
Family
ID=67682482
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019010484A MX2019010484A (es) | 2017-04-11 | 2017-12-11 | Niveles de acidos grasos omega-3 y vitamina d para identificar y atenuar el envejecimiento congnitivo en individuos. |
MX2019010828A MX2019010828A (es) | 2017-04-11 | 2018-04-05 | Metodos para identificar la predisposicion al declive cognitivo y agentes para reducir o prevenir el declive cognitivo o para mejorar la capacidad cognitiva. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019010828A MX2019010828A (es) | 2017-04-11 | 2018-04-05 | Metodos para identificar la predisposicion al declive cognitivo y agentes para reducir o prevenir el declive cognitivo o para mejorar la capacidad cognitiva. |
Country Status (8)
Country | Link |
---|---|
US (6) | US20210128587A1 (es) |
EP (3) | EP3609490A1 (es) |
JP (6) | JP7270546B2 (es) |
CN (3) | CN110381935A (es) |
AU (4) | AU2017408873A1 (es) |
BR (3) | BR112019017949A2 (es) |
CA (3) | CA3054846A1 (es) |
MX (2) | MX2019010484A (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210128587A1 (en) * | 2017-04-11 | 2021-05-06 | Societe Des Produits Nestle S.A. | Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals |
CN113252806B (zh) * | 2021-03-25 | 2023-08-29 | 嘉兴学院 | S-腺苷同型半胱氨酸在制备用于诊断或治疗川崎病的产品中的用途 |
Family Cites Families (30)
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US20070004670A1 (en) * | 1998-07-31 | 2007-01-04 | Richard Wurtman | Compositions containing citicoline, and methods of use thereof |
GB0016460D0 (en) * | 2000-07-04 | 2000-08-23 | Axis Shield Asa | Assay |
US6964969B2 (en) * | 2001-04-19 | 2005-11-15 | Mccleary Edward Larry | Composition and method for treating impaired or deteriorating neurological function |
US8017657B1 (en) * | 2001-09-07 | 2011-09-13 | Advanced Medical Instruments | Composition for the treatment and prevention of endothelial dysfunction |
JPWO2004075905A1 (ja) * | 2003-02-26 | 2006-06-01 | 協和醗酵工業株式会社 | 筋肉増強剤および筋肉減衰の予防または治療剤 |
US20070078114A1 (en) * | 2005-09-02 | 2007-04-05 | Myriad Genetics, Incorporated | Combination therapy for alzheimer's disease and other diseases |
WO2009002148A1 (en) * | 2007-06-27 | 2008-12-31 | N.V. Nutricia | Food composition for prodromal dementia patients |
MX2010000224A (es) | 2007-06-26 | 2010-05-03 | Nutricia Nv | Mejoramiento de la memoria en individuos con mini-examen de estado mental de 24-26. |
CA2701179C (en) * | 2007-10-04 | 2021-03-16 | Nestec S.A. | Compositions and methods for enhancing cognitive function |
US20100233304A1 (en) * | 2008-01-04 | 2010-09-16 | Yuanlong Pan | Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing cognitive and related functions |
NZ735173A (en) | 2008-12-09 | 2022-10-28 | Stephanie Fryar Williams | Biomarkers for the diagnosis and/or prediction of susceptibility to mental and neurodegenerative disorders |
EP2384114A4 (en) * | 2008-12-31 | 2013-10-23 | Nitromega Corp | NUTRACEUTICALS CONTAINING NITROPTANT ACIDS |
CN101897706A (zh) * | 2009-05-27 | 2010-12-01 | 北京奥萨医药研究中心有限公司 | 含有叶酸和b族维生素的组合物及其用途 |
EP2440201A1 (en) * | 2009-06-10 | 2012-04-18 | Energy4life Ag | Methods and compositions for treating insulin resistance, diabetes mellitus type 2, metabolic syndrome and related disorders |
US8563609B2 (en) * | 2010-05-13 | 2013-10-22 | Nitromega Corp. | Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline |
WO2012049222A2 (en) | 2010-10-12 | 2012-04-19 | Vifor Sa | Novel omega-3 and omega-6 fatty acid compositions and uses thereof |
JP2014515011A (ja) * | 2011-03-18 | 2014-06-26 | ネステク ソシエテ アノニム | 加齢に伴う疾病を改善するのに有用な組成物及び方法 |
RU2014121888A (ru) * | 2011-10-31 | 2015-12-10 | Н.В. Нютрисиа | Композиция для улучшения оценки батареи нейропсихологических тестов |
BR112015002309A2 (pt) * | 2012-08-07 | 2017-07-04 | Buck Inst Res Aging | formulação de múltiplos componentes para aprimorar a função neurológica |
FR3002044A1 (fr) * | 2013-02-08 | 2014-08-15 | Centre Nat Rech Scient | Marqueur dyrk1a pour la maladie d'alzheimer |
JP2016514673A (ja) | 2013-03-15 | 2016-05-23 | バック・インスティテュート・フォー・リサーチ・オン・エイジング | 改善された認知機能サプリメント |
US20140271844A1 (en) * | 2013-03-15 | 2014-09-18 | Nitromega Corp. | Compositions containing nitro fatty acids |
EP2899543A1 (en) | 2014-01-28 | 2015-07-29 | Predemtec GmbH | Biomarker and methods for early diagnosis of Alzheimer's disease |
GB201405033D0 (en) * | 2014-03-20 | 2014-05-07 | Isis Innovation | Combination therapy |
EP3310349B1 (en) * | 2015-06-22 | 2021-01-13 | Société des Produits Nestlé S.A. | Compositions and methods for enhancing neurogenesis in animals |
WO2017004436A2 (en) * | 2015-07-01 | 2017-01-05 | The Regents Of The University Of California | A therapeutic system comprising pharmaceuticals in combination with metabolic enhancement for neurodegeneration |
US20180268940A1 (en) * | 2015-09-25 | 2018-09-20 | Buck Institute For Research On Aging | Compositions and methods for specific biological cognitive functions in neurodegenerative diseases |
AU2017270131B2 (en) * | 2016-05-27 | 2023-03-09 | Société des Produits Nestlé S.A. | Nutritional composition for treating or preventing impaired mobility |
US10821130B2 (en) * | 2016-09-29 | 2020-11-03 | Societe Des Produits Nestle S.A. | Omega 3 fatty acids, no releasing compound and vitamin B12 as neuroprotectant in patients with no dementia |
US20210128587A1 (en) | 2017-04-11 | 2021-05-06 | Societe Des Produits Nestle S.A. | Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals |
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2017
- 2017-12-11 US US16/603,749 patent/US20210128587A1/en not_active Abandoned
- 2017-12-11 CA CA3054846A patent/CA3054846A1/en active Pending
- 2017-12-11 EP EP17816680.7A patent/EP3609490A1/en not_active Withdrawn
- 2017-12-11 JP JP2019550821A patent/JP7270546B2/ja active Active
- 2017-12-11 BR BR112019017949A patent/BR112019017949A2/pt active Search and Examination
- 2017-12-11 AU AU2017408873A patent/AU2017408873A1/en not_active Abandoned
- 2017-12-11 CN CN201780087975.4A patent/CN110381935A/zh active Pending
- 2017-12-11 MX MX2019010484A patent/MX2019010484A/es unknown
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2018
- 2018-04-05 CA CA3054869A patent/CA3054869A1/en active Pending
- 2018-04-05 CN CN201880022932.2A patent/CN110475553A/zh active Pending
- 2018-04-05 BR BR112019018729A patent/BR112019018729A2/pt active Search and Examination
- 2018-04-05 JP JP2019550713A patent/JP2020516586A/ja active Pending
- 2018-04-05 EP EP18714287.2A patent/EP3609491A2/en active Pending
- 2018-04-05 AU AU2018251092A patent/AU2018251092B2/en active Active
- 2018-04-05 JP JP2019551444A patent/JP7270547B2/ja active Active
- 2018-04-05 MX MX2019010828A patent/MX2019010828A/es unknown
- 2018-04-05 EP EP18714289.8A patent/EP3609487A1/en active Pending
- 2018-04-05 US US16/603,688 patent/US20210263048A1/en active Pending
- 2018-04-05 BR BR112019020008A patent/BR112019020008A2/pt unknown
- 2018-04-05 CA CA3054864A patent/CA3054864A1/en active Pending
- 2018-04-05 US US16/604,055 patent/US20200054665A1/en not_active Abandoned
- 2018-04-05 CN CN201880018724.5A patent/CN110430873A/zh active Pending
- 2018-04-05 AU AU2018251094A patent/AU2018251094B2/en active Active
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2022
- 2022-08-15 JP JP2022129345A patent/JP7434459B2/ja active Active
- 2022-08-15 JP JP2022129344A patent/JP7434458B2/ja active Active
- 2022-10-06 US US17/960,966 patent/US20230028607A1/en active Pending
- 2022-12-23 JP JP2022206897A patent/JP2023030130A/ja active Pending
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2023
- 2023-05-15 US US18/197,402 patent/US20230310488A1/en active Pending
- 2023-10-10 US US18/378,404 patent/US20240041915A1/en active Pending
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2024
- 2024-02-12 AU AU2024200882A patent/AU2024200882A1/en active Pending
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