JP2022107023A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2022107023A5 JP2022107023A5 JP2022080860A JP2022080860A JP2022107023A5 JP 2022107023 A5 JP2022107023 A5 JP 2022107023A5 JP 2022080860 A JP2022080860 A JP 2022080860A JP 2022080860 A JP2022080860 A JP 2022080860A JP 2022107023 A5 JP2022107023 A5 JP 2022107023A5
- Authority
- JP
- Japan
- Prior art keywords
- lobe
- liver
- containing portion
- regenerative cells
- perfused decellularized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 9
- 230000001172 regenerating effect Effects 0.000 claims 9
- 210000004185 liver Anatomy 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 5
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 5
- 210000002744 extracellular matrix Anatomy 0.000 claims 5
- 210000005161 hepatic lobe Anatomy 0.000 claims 3
- 210000000130 stem cell Anatomy 0.000 claims 2
- 230000004069 differentiation Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000003494 hepatocyte Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 210000003240 portal vein Anatomy 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023204715A JP2024015176A (ja) | 2009-03-31 | 2023-12-04 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2025046714A JP2025089394A (ja) | 2009-03-31 | 2025-03-21 | 臓器および組織を脱細胞化および再細胞化する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21161309P | 2009-03-31 | 2009-03-31 | |
| US61/211,613 | 2009-03-31 | ||
| JP2019095766A JP2019134723A (ja) | 2009-03-31 | 2019-05-22 | 臓器および組織を脱細胞化および再細胞化する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019095766A Division JP2019134723A (ja) | 2009-03-31 | 2019-05-22 | 臓器および組織を脱細胞化および再細胞化する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204715A Division JP2024015176A (ja) | 2009-03-31 | 2023-12-04 | 臓器および組織を脱細胞化および再細胞化する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022107023A JP2022107023A (ja) | 2022-07-20 |
| JP2022107023A5 true JP2022107023A5 (enExample) | 2022-12-12 |
Family
ID=42983078
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012503673A Pending JP2012522511A (ja) | 2009-03-31 | 2010-03-31 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2015164446A Pending JP2016039903A (ja) | 2009-03-31 | 2015-08-24 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2017147965A Pending JP2017195900A (ja) | 2009-03-31 | 2017-07-31 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2019095766A Pending JP2019134723A (ja) | 2009-03-31 | 2019-05-22 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2022080860A Pending JP2022107023A (ja) | 2009-03-31 | 2022-05-17 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2023204715A Pending JP2024015176A (ja) | 2009-03-31 | 2023-12-04 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2025046714A Pending JP2025089394A (ja) | 2009-03-31 | 2025-03-21 | 臓器および組織を脱細胞化および再細胞化する方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012503673A Pending JP2012522511A (ja) | 2009-03-31 | 2010-03-31 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2015164446A Pending JP2016039903A (ja) | 2009-03-31 | 2015-08-24 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2017147965A Pending JP2017195900A (ja) | 2009-03-31 | 2017-07-31 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2019095766A Pending JP2019134723A (ja) | 2009-03-31 | 2019-05-22 | 臓器および組織を脱細胞化および再細胞化する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023204715A Pending JP2024015176A (ja) | 2009-03-31 | 2023-12-04 | 臓器および組織を脱細胞化および再細胞化する方法 |
| JP2025046714A Pending JP2025089394A (ja) | 2009-03-31 | 2025-03-21 | 臓器および組織を脱細胞化および再細胞化する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20120183944A1 (enExample) |
| EP (1) | EP2413946A2 (enExample) |
| JP (7) | JP2012522511A (enExample) |
| KR (1) | KR20120023626A (enExample) |
| CN (1) | CN102448476A (enExample) |
| AU (1) | AU2010236855C1 (enExample) |
| CA (1) | CA2757457C (enExample) |
| IL (1) | IL215463A0 (enExample) |
| MX (1) | MX2011010197A (enExample) |
| RU (1) | RU2011143730A (enExample) |
| SG (2) | SG174969A1 (enExample) |
| WO (1) | WO2010120539A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2384721T3 (es) | 2005-08-26 | 2012-07-11 | Regents Of The University Of Minnesota | Descelularización y recelularización de órganos y tejidos |
| EP2588592B1 (en) * | 2010-06-30 | 2017-09-06 | Miromatrix Medical Inc. | Use of perfusion decellularized organs for matched recellularization |
| SG188369A1 (en) | 2010-09-01 | 2013-04-30 | Univ Minnesota | Methods of recellularizing a tissue or organ for improved transplantability |
| WO2012166668A1 (en) * | 2011-05-27 | 2012-12-06 | Christian Kazanecki | Bioartificial proximal tubule systems and methods of use |
| CN103173920B (zh) * | 2011-12-26 | 2014-08-27 | 广野精机有限公司 | 纬纱输送控线装置 |
| EP2809152B1 (en) | 2012-02-01 | 2019-11-20 | Nayacure Therapeutics Ltd | Method for inducing immune tolerance to organ transplants |
| EP2838986A4 (en) * | 2012-04-18 | 2015-12-23 | Gen Hospital Corp | BIOARTIFICIAL FILTRATION ORGAN |
| EP2841010B1 (en) | 2012-04-24 | 2023-08-23 | Harvard Apparatus Regenerative Technology, Inc. | Supports for engineered tissue scaffolds |
| US9290738B2 (en) | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
| US10111740B2 (en) | 2012-08-21 | 2018-10-30 | Regents Of The University Of Minnesota | Decellularized biologically-engineered tubular grafts |
| HK1217663A1 (zh) | 2013-01-09 | 2017-01-20 | Harvard Apparatus Regenerative Technology, Inc. | 合成支架 |
| ES2831756T3 (es) * | 2013-03-15 | 2021-06-09 | Miromatrix Medical Inc | Uso de hígado descelularizado por perfusión para la recelularización de células de islotes |
| US9888680B2 (en) | 2013-04-04 | 2018-02-13 | The Trustees Of Columbia University In The City Of New York | Functional recovery of human lungs for transplantation |
| RU2539918C1 (ru) * | 2013-11-29 | 2015-01-27 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Способ получения тканеспецифического матрикса для тканевой инженерии паренхиматозного органа |
| CN103751843B (zh) * | 2013-12-05 | 2015-09-16 | 南方医科大学珠江医院 | 制备全肝脏生物支架的试剂盒及全肝脏生物支架制备方法 |
| KR101637548B1 (ko) | 2013-12-24 | 2016-07-20 | 연세대학교 산학협력단 | 세포 배양 및 세포 분화를 위한 탈세포화 기관 매트릭스 동결건조 분쇄물 및 이의 제조 방법 |
| CA2942714C (en) * | 2014-03-14 | 2023-09-05 | The General Hospital Corporation | Lung bioreactor |
| CN103966092A (zh) * | 2014-04-10 | 2014-08-06 | 欧东波 | 器官脱细胞循环灌流再生培养瓶 |
| AU2015265954A1 (en) * | 2014-05-27 | 2017-01-12 | Novahep Ab | Bioengineered allogeneic valve |
| WO2016036764A2 (en) * | 2014-09-02 | 2016-03-10 | United Therapeutics Corporation | Automated bioreactor system, system for automatically implementing protocol for decellularizing organ, and waste decontamination system |
| WO2016048243A1 (en) * | 2014-09-23 | 2016-03-31 | Nanyang Technological University | A bioreactor module, a bioreactor system and methods for thick tissue seeding and cultivation in an hirearchical organization and physiological mimiking conditions |
| JP2016185115A (ja) * | 2015-03-27 | 2016-10-27 | シスメックス株式会社 | 臓器灌流方法および臓器灌流装置 |
| CN106148270B (zh) * | 2015-04-13 | 2019-09-06 | 中国科学院大连化学物理研究所 | 一种用于生物人工肝支持系统的三维微肝组织单元的构建方法 |
| CN104771788B (zh) * | 2015-05-05 | 2017-08-25 | 北京帝康医药投资管理有限公司 | 一种基于大网膜脱细胞基质的组织工程皮肤及其构建方法 |
| CN106693055A (zh) * | 2015-07-26 | 2017-05-24 | 复旦大学附属华山医院 | 一种小脑脱细胞再生生物支架及其制备方法和用途 |
| ES2749160T3 (es) | 2015-09-11 | 2020-03-19 | Massachusetts Gen Hospital | Regeneración de un lecho vascular pulmonar funcional |
| WO2017136786A1 (en) * | 2016-02-05 | 2017-08-10 | The Trustees Of Columbia University In The City Of New York | Rigionally specific tissua-derived extracellular metrix |
| WO2017176919A1 (en) | 2016-04-05 | 2017-10-12 | Regents Of The University Of Minnesota | Engineered tissues having structural components embedded therein, and methods of making and using |
| ITUA20164238A1 (it) * | 2016-06-09 | 2017-12-09 | G F S P A | Metodo e apparato per la decellularizzazione di organi |
| CN107621462B (zh) * | 2016-07-13 | 2020-03-31 | 王志伟 | 一种组织透明化液sut及其制备和应用 |
| CN106267345B (zh) * | 2016-08-04 | 2019-03-26 | 中国人民解放军第三军医大学第一附属医院 | 一种具有生物活性的再生期器官去细胞生物支架的制备方法及其产品和应用 |
| EP3509651B1 (en) | 2016-09-06 | 2022-12-28 | Miromatrix Medical Inc. | Use of resected liver serum for whole liver engineering |
| CN107412865A (zh) * | 2016-10-27 | 2017-12-01 | 浙江保尔曼生物科技有限公司 | 高强度的具有抗凝血功能的去细胞化肾脏生物支架及制备方法 |
| CN107096070B (zh) * | 2017-03-09 | 2020-08-21 | 中国医学科学院阜外医院 | 一种脱细胞肺支架及其制备方法 |
| WO2019168913A1 (en) * | 2018-02-28 | 2019-09-06 | Pop Test Oncology Llc | Medical devices and uses thereof |
| CN108465126A (zh) * | 2018-05-25 | 2018-08-31 | 中国人民解放军总医院 | 模拟生理过程的膀胱脱细胞基质的制备装置 |
| WO2019241499A1 (en) | 2018-06-13 | 2019-12-19 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| WO2020158794A1 (ja) * | 2019-01-30 | 2020-08-06 | 国立大学法人 長崎大学 | 疾患モデル |
| WO2020191374A1 (en) * | 2019-03-21 | 2020-09-24 | Miromatrix Medical Inc. | Improved decellularization of isolated organs |
| EP3975936A4 (en) | 2019-05-28 | 2022-08-03 | Regents of the University of Minnesota | ENGINEERING VALVE AND METHOD OF MANUFACTURE |
| EP4017549A1 (en) * | 2019-08-19 | 2022-06-29 | Miromatrix Medical Inc. | Sealing of decellularized and recellularized engineered organ grafts |
| AU2021336557A1 (en) * | 2020-09-04 | 2023-05-18 | Annoviant, Llc | Systems and methods for processing tissue |
| US11998662B1 (en) | 2021-06-09 | 2024-06-04 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
| US12383657B1 (en) | 2021-06-09 | 2025-08-12 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
| CN114949357B (zh) * | 2022-05-20 | 2023-08-01 | 上海市第十人民医院 | 一种阴茎脱细胞支架及其制备方法和应用 |
| CN120548201A (zh) | 2022-11-18 | 2025-08-26 | 万益特健康有限责任公司 | 用于器官支持的体外血液处理 |
| CN117100912A (zh) * | 2023-06-08 | 2023-11-24 | 北京科昕恒业生物科技有限公司 | 一种肺脏脱细胞基质及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1176400A (ja) * | 1997-09-09 | 1999-03-23 | Masahito Nagaki | 人工臓器 |
| JP4222658B2 (ja) * | 1998-06-23 | 2009-02-12 | テルモ株式会社 | 細胞支持基材、培養装置および液体処理装置 |
| US6479064B1 (en) * | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
| US20050249816A1 (en) * | 1999-12-29 | 2005-11-10 | Wake Forest University Health Services | Tissue engineered liver constructs |
| WO2002088331A1 (en) * | 2001-05-01 | 2002-11-07 | Universite Du Quebec A Montreal | Tridimensional biocompatible support structure for bioartificial organs and uses thereof |
| US20030187515A1 (en) * | 2002-03-26 | 2003-10-02 | Hariri Robert J. | Collagen biofabric and methods of preparing and using the collagen biofabric |
| US20050130300A1 (en) * | 2002-04-04 | 2005-06-16 | Daiichi Pure Chemicals Co., Ltd. | Method of culturing liver cells over long time |
| WO2006126219A1 (en) * | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| WO2007002228A1 (en) * | 2005-06-23 | 2007-01-04 | Massachusetts Institute Of Technology | Methods for ex vivo propagation of adult hepatic stem cells |
| ES2384721T3 (es) * | 2005-08-26 | 2012-07-11 | Regents Of The University Of Minnesota | Descelularización y recelularización de órganos y tejidos |
| JP4599315B2 (ja) * | 2006-02-23 | 2010-12-15 | クラレメディカル株式会社 | バイオ人工臓器 |
-
2010
- 2010-03-31 SG SG2011070810A patent/SG174969A1/en unknown
- 2010-03-31 CA CA2757457A patent/CA2757457C/en active Active
- 2010-03-31 CN CN2010800248990A patent/CN102448476A/zh active Pending
- 2010-03-31 MX MX2011010197A patent/MX2011010197A/es active IP Right Grant
- 2010-03-31 RU RU2011143730/15A patent/RU2011143730A/ru unknown
- 2010-03-31 WO PCT/US2010/029463 patent/WO2010120539A2/en not_active Ceased
- 2010-03-31 AU AU2010236855A patent/AU2010236855C1/en active Active
- 2010-03-31 SG SG10201401131WA patent/SG10201401131WA/en unknown
- 2010-03-31 JP JP2012503673A patent/JP2012522511A/ja active Pending
- 2010-03-31 KR KR1020117025607A patent/KR20120023626A/ko not_active Withdrawn
- 2010-03-31 US US13/262,286 patent/US20120183944A1/en not_active Abandoned
- 2010-03-31 EP EP10723848A patent/EP2413946A2/en not_active Withdrawn
-
2011
- 2011-10-02 IL IL215463A patent/IL215463A0/en unknown
-
2015
- 2015-08-24 JP JP2015164446A patent/JP2016039903A/ja active Pending
-
2017
- 2017-07-31 JP JP2017147965A patent/JP2017195900A/ja active Pending
-
2019
- 2019-05-22 JP JP2019095766A patent/JP2019134723A/ja active Pending
-
2021
- 2021-08-04 US US17/394,243 patent/US20220062349A1/en active Pending
-
2022
- 2022-05-17 JP JP2022080860A patent/JP2022107023A/ja active Pending
-
2023
- 2023-12-04 JP JP2023204715A patent/JP2024015176A/ja active Pending
-
2025
- 2025-03-21 JP JP2025046714A patent/JP2025089394A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022107023A5 (enExample) | ||
| JP2024015176A5 (enExample) | ||
| Zhang et al. | Stem cell therapy and tissue engineering strategies using cell aggregates and decellularized scaffolds for the rescue of liver failure | |
| JP2025089394A5 (enExample) | ||
| Tsolaki et al. | Stem cell-based regenerative opportunities for the liver: State of the art and beyond | |
| RU2011143730A (ru) | Децеллюляризации и рецеллюляризация органов и тканей | |
| Qiang et al. | Intravenous transplantation of mesenchymal stem cells attenuates oleic acid induced acute lung injury in rats | |
| TW200920328A (en) | Therapeutic hybrid implantable devices | |
| JP2012522511A5 (enExample) | ||
| Liang et al. | Migration of resident cardiac stem cells in myocardial infarction | |
| Swim et al. | Amnion-based scaffold with enhanced strength and biocompatibility for in vivo vascular repair | |
| Colby et al. | Developmental anatomy of direct shoot organogenesis from leaf petioles of Vitis vinifera (Vitaceae) | |
| WO2023184818A1 (zh) | 米托蒽醌在制备预防或治疗急性移植物抗宿主病药物中的应用 | |
| CN120053693A (zh) | 植物-细菌杂化外囊泡复合水凝胶微针及其制备与应用 | |
| CN113215102A (zh) | 一种类器官的培养基及培养方法 | |
| Hsieh et al. | HGF/heparin-immobilized decellularized liver matrices as novel hepatic patches for hepatocyte regeneration in an acute liver injury model | |
| CN108201538A (zh) | 褪黑素在促进心肌干细胞移植治疗心肌梗死中的应用 | |
| CN104304239B (zh) | 一种提高金线莲类原球茎保存效果的方法 | |
| CN1271923C (zh) | 一种薰衣草组织培养方法 | |
| JP2008126087A (ja) | 心筋細胞移植実施プロセス | |
| CN106701665A (zh) | 人胎盘亚全能干细胞诱导分化为心肌细胞的方法及其应用 | |
| CN104818247A (zh) | 一种间充质干细胞的培养方法及用途 | |
| CN114190362B (zh) | 一种胎盘保存液及胎盘的保存方法 | |
| JP2009509979A5 (enExample) | ||
| Ludwig | Islet immunoisolation by macroencapsulation |