IL215463A0 - Decellularization and recellularization of organs and tissues - Google Patents

Decellularization and recellularization of organs and tissues

Info

Publication number
IL215463A0
IL215463A0 IL215463A IL21546311A IL215463A0 IL 215463 A0 IL215463 A0 IL 215463A0 IL 215463 A IL215463 A IL 215463A IL 21546311 A IL21546311 A IL 21546311A IL 215463 A0 IL215463 A0 IL 215463A0
Authority
IL
Israel
Prior art keywords
recellularization
decellularization
organs
tissues
Prior art date
Application number
IL215463A
Other languages
English (en)
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of IL215463A0 publication Critical patent/IL215463A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
IL215463A 2009-03-31 2011-10-02 Decellularization and recellularization of organs and tissues IL215463A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21161309P 2009-03-31 2009-03-31
PCT/US2010/029463 WO2010120539A2 (en) 2009-03-31 2010-03-31 Decellularization and recellularization of organs and tissues

Publications (1)

Publication Number Publication Date
IL215463A0 true IL215463A0 (en) 2011-12-29

Family

ID=42983078

Family Applications (1)

Application Number Title Priority Date Filing Date
IL215463A IL215463A0 (en) 2009-03-31 2011-10-02 Decellularization and recellularization of organs and tissues

Country Status (12)

Country Link
US (2) US20120183944A1 (enExample)
EP (1) EP2413946A2 (enExample)
JP (7) JP2012522511A (enExample)
KR (1) KR20120023626A (enExample)
CN (1) CN102448476A (enExample)
AU (1) AU2010236855C1 (enExample)
CA (1) CA2757457C (enExample)
IL (1) IL215463A0 (enExample)
MX (1) MX2011010197A (enExample)
RU (1) RU2011143730A (enExample)
SG (2) SG174969A1 (enExample)
WO (1) WO2010120539A2 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2384721T3 (es) 2005-08-26 2012-07-11 Regents Of The University Of Minnesota Descelularización y recelularización de órganos y tejidos
EP2588592B1 (en) * 2010-06-30 2017-09-06 Miromatrix Medical Inc. Use of perfusion decellularized organs for matched recellularization
SG188369A1 (en) 2010-09-01 2013-04-30 Univ Minnesota Methods of recellularizing a tissue or organ for improved transplantability
WO2012166668A1 (en) * 2011-05-27 2012-12-06 Christian Kazanecki Bioartificial proximal tubule systems and methods of use
CN103173920B (zh) * 2011-12-26 2014-08-27 广野精机有限公司 纬纱输送控线装置
EP2809152B1 (en) 2012-02-01 2019-11-20 Nayacure Therapeutics Ltd Method for inducing immune tolerance to organ transplants
EP2838986A4 (en) * 2012-04-18 2015-12-23 Gen Hospital Corp BIOARTIFICIAL FILTRATION ORGAN
EP2841010B1 (en) 2012-04-24 2023-08-23 Harvard Apparatus Regenerative Technology, Inc. Supports for engineered tissue scaffolds
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
US10111740B2 (en) 2012-08-21 2018-10-30 Regents Of The University Of Minnesota Decellularized biologically-engineered tubular grafts
HK1217663A1 (zh) 2013-01-09 2017-01-20 Harvard Apparatus Regenerative Technology, Inc. 合成支架
ES2831756T3 (es) * 2013-03-15 2021-06-09 Miromatrix Medical Inc Uso de hígado descelularizado por perfusión para la recelularización de células de islotes
US9888680B2 (en) 2013-04-04 2018-02-13 The Trustees Of Columbia University In The City Of New York Functional recovery of human lungs for transplantation
RU2539918C1 (ru) * 2013-11-29 2015-01-27 Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации Способ получения тканеспецифического матрикса для тканевой инженерии паренхиматозного органа
CN103751843B (zh) * 2013-12-05 2015-09-16 南方医科大学珠江医院 制备全肝脏生物支架的试剂盒及全肝脏生物支架制备方法
KR101637548B1 (ko) 2013-12-24 2016-07-20 연세대학교 산학협력단 세포 배양 및 세포 분화를 위한 탈세포화 기관 매트릭스 동결건조 분쇄물 및 이의 제조 방법
CA2942714C (en) * 2014-03-14 2023-09-05 The General Hospital Corporation Lung bioreactor
CN103966092A (zh) * 2014-04-10 2014-08-06 欧东波 器官脱细胞循环灌流再生培养瓶
AU2015265954A1 (en) * 2014-05-27 2017-01-12 Novahep Ab Bioengineered allogeneic valve
WO2016036764A2 (en) * 2014-09-02 2016-03-10 United Therapeutics Corporation Automated bioreactor system, system for automatically implementing protocol for decellularizing organ, and waste decontamination system
WO2016048243A1 (en) * 2014-09-23 2016-03-31 Nanyang Technological University A bioreactor module, a bioreactor system and methods for thick tissue seeding and cultivation in an hirearchical organization and physiological mimiking conditions
JP2016185115A (ja) * 2015-03-27 2016-10-27 シスメックス株式会社 臓器灌流方法および臓器灌流装置
CN106148270B (zh) * 2015-04-13 2019-09-06 中国科学院大连化学物理研究所 一种用于生物人工肝支持系统的三维微肝组织单元的构建方法
CN104771788B (zh) * 2015-05-05 2017-08-25 北京帝康医药投资管理有限公司 一种基于大网膜脱细胞基质的组织工程皮肤及其构建方法
CN106693055A (zh) * 2015-07-26 2017-05-24 复旦大学附属华山医院 一种小脑脱细胞再生生物支架及其制备方法和用途
ES2749160T3 (es) 2015-09-11 2020-03-19 Massachusetts Gen Hospital Regeneración de un lecho vascular pulmonar funcional
WO2017136786A1 (en) * 2016-02-05 2017-08-10 The Trustees Of Columbia University In The City Of New York Rigionally specific tissua-derived extracellular metrix
WO2017176919A1 (en) 2016-04-05 2017-10-12 Regents Of The University Of Minnesota Engineered tissues having structural components embedded therein, and methods of making and using
ITUA20164238A1 (it) * 2016-06-09 2017-12-09 G F S P A Metodo e apparato per la decellularizzazione di organi
CN107621462B (zh) * 2016-07-13 2020-03-31 王志伟 一种组织透明化液sut及其制备和应用
CN106267345B (zh) * 2016-08-04 2019-03-26 中国人民解放军第三军医大学第一附属医院 一种具有生物活性的再生期器官去细胞生物支架的制备方法及其产品和应用
EP3509651B1 (en) 2016-09-06 2022-12-28 Miromatrix Medical Inc. Use of resected liver serum for whole liver engineering
CN107412865A (zh) * 2016-10-27 2017-12-01 浙江保尔曼生物科技有限公司 高强度的具有抗凝血功能的去细胞化肾脏生物支架及制备方法
CN107096070B (zh) * 2017-03-09 2020-08-21 中国医学科学院阜外医院 一种脱细胞肺支架及其制备方法
WO2019168913A1 (en) * 2018-02-28 2019-09-06 Pop Test Oncology Llc Medical devices and uses thereof
CN108465126A (zh) * 2018-05-25 2018-08-31 中国人民解放军总医院 模拟生理过程的膀胱脱细胞基质的制备装置
WO2019241499A1 (en) 2018-06-13 2019-12-19 Miromatrix Medical Inc. Fistula filler and deployment system
WO2020158794A1 (ja) * 2019-01-30 2020-08-06 国立大学法人 長崎大学 疾患モデル
WO2020191374A1 (en) * 2019-03-21 2020-09-24 Miromatrix Medical Inc. Improved decellularization of isolated organs
EP3975936A4 (en) 2019-05-28 2022-08-03 Regents of the University of Minnesota ENGINEERING VALVE AND METHOD OF MANUFACTURE
EP4017549A1 (en) * 2019-08-19 2022-06-29 Miromatrix Medical Inc. Sealing of decellularized and recellularized engineered organ grafts
AU2021336557A1 (en) * 2020-09-04 2023-05-18 Annoviant, Llc Systems and methods for processing tissue
US11998662B1 (en) 2021-06-09 2024-06-04 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
US12383657B1 (en) 2021-06-09 2025-08-12 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods
CN114949357B (zh) * 2022-05-20 2023-08-01 上海市第十人民医院 一种阴茎脱细胞支架及其制备方法和应用
CN120548201A (zh) 2022-11-18 2025-08-26 万益特健康有限责任公司 用于器官支持的体外血液处理
CN117100912A (zh) * 2023-06-08 2023-11-24 北京科昕恒业生物科技有限公司 一种肺脏脱细胞基质及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1176400A (ja) * 1997-09-09 1999-03-23 Masahito Nagaki 人工臓器
JP4222658B2 (ja) * 1998-06-23 2009-02-12 テルモ株式会社 細胞支持基材、培養装置および液体処理装置
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US20050249816A1 (en) * 1999-12-29 2005-11-10 Wake Forest University Health Services Tissue engineered liver constructs
WO2002088331A1 (en) * 2001-05-01 2002-11-07 Universite Du Quebec A Montreal Tridimensional biocompatible support structure for bioartificial organs and uses thereof
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US20050130300A1 (en) * 2002-04-04 2005-06-16 Daiichi Pure Chemicals Co., Ltd. Method of culturing liver cells over long time
WO2006126219A1 (en) * 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
WO2007002228A1 (en) * 2005-06-23 2007-01-04 Massachusetts Institute Of Technology Methods for ex vivo propagation of adult hepatic stem cells
ES2384721T3 (es) * 2005-08-26 2012-07-11 Regents Of The University Of Minnesota Descelularización y recelularización de órganos y tejidos
JP4599315B2 (ja) * 2006-02-23 2010-12-15 クラレメディカル株式会社 バイオ人工臓器

Also Published As

Publication number Publication date
SG10201401131WA (en) 2014-07-30
CN102448476A (zh) 2012-05-09
JP2016039903A (ja) 2016-03-24
EP2413946A2 (en) 2012-02-08
JP2017195900A (ja) 2017-11-02
CA2757457A1 (en) 2010-10-21
WO2010120539A3 (en) 2011-02-03
US20120183944A1 (en) 2012-07-19
RU2011143730A (ru) 2013-05-10
JP2025089394A (ja) 2025-06-12
KR20120023626A (ko) 2012-03-13
JP2024015176A (ja) 2024-02-01
JP2022107023A (ja) 2022-07-20
CA2757457C (en) 2018-05-29
JP2019134723A (ja) 2019-08-15
AU2010236855B2 (en) 2014-09-11
AU2010236855C1 (en) 2015-04-02
WO2010120539A2 (en) 2010-10-21
SG174969A1 (en) 2011-11-28
MX2011010197A (es) 2011-11-18
AU2010236855A1 (en) 2011-10-27
US20220062349A1 (en) 2022-03-03
JP2012522511A (ja) 2012-09-27

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