JP2012522511A - 臓器および組織を脱細胞化および再細胞化する方法 - Google Patents

臓器および組織を脱細胞化および再細胞化する方法 Download PDF

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JP2012522511A
JP2012522511A JP2012503673A JP2012503673A JP2012522511A JP 2012522511 A JP2012522511 A JP 2012522511A JP 2012503673 A JP2012503673 A JP 2012503673A JP 2012503673 A JP2012503673 A JP 2012503673A JP 2012522511 A JP2012522511 A JP 2012522511A
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decellularized
cells
organ
liver
heart
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JP2012522511A5 (enExample
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ドリス テイラー
ハラルド オット
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University of Minnesota Twin Cities
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University of Minnesota System
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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JP2012503673A 2009-03-31 2010-03-31 臓器および組織を脱細胞化および再細胞化する方法 Pending JP2012522511A (ja)

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US21161309P 2009-03-31 2009-03-31
US61/211,613 2009-03-31
PCT/US2010/029463 WO2010120539A2 (en) 2009-03-31 2010-03-31 Decellularization and recellularization of organs and tissues

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JP2012522511A5 JP2012522511A5 (enExample) 2013-05-23

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JP2012503673A Pending JP2012522511A (ja) 2009-03-31 2010-03-31 臓器および組織を脱細胞化および再細胞化する方法
JP2015164446A Pending JP2016039903A (ja) 2009-03-31 2015-08-24 臓器および組織を脱細胞化および再細胞化する方法
JP2017147965A Pending JP2017195900A (ja) 2009-03-31 2017-07-31 臓器および組織を脱細胞化および再細胞化する方法
JP2019095766A Pending JP2019134723A (ja) 2009-03-31 2019-05-22 臓器および組織を脱細胞化および再細胞化する方法
JP2022080860A Pending JP2022107023A (ja) 2009-03-31 2022-05-17 臓器および組織を脱細胞化および再細胞化する方法
JP2023204715A Pending JP2024015176A (ja) 2009-03-31 2023-12-04 臓器および組織を脱細胞化および再細胞化する方法
JP2025046714A Pending JP2025089394A (ja) 2009-03-31 2025-03-21 臓器および組織を脱細胞化および再細胞化する方法

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JP2015164446A Pending JP2016039903A (ja) 2009-03-31 2015-08-24 臓器および組織を脱細胞化および再細胞化する方法
JP2017147965A Pending JP2017195900A (ja) 2009-03-31 2017-07-31 臓器および組織を脱細胞化および再細胞化する方法
JP2019095766A Pending JP2019134723A (ja) 2009-03-31 2019-05-22 臓器および組織を脱細胞化および再細胞化する方法
JP2022080860A Pending JP2022107023A (ja) 2009-03-31 2022-05-17 臓器および組織を脱細胞化および再細胞化する方法
JP2023204715A Pending JP2024015176A (ja) 2009-03-31 2023-12-04 臓器および組織を脱細胞化および再細胞化する方法
JP2025046714A Pending JP2025089394A (ja) 2009-03-31 2025-03-21 臓器および組織を脱細胞化および再細胞化する方法

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US (2) US20120183944A1 (enExample)
EP (1) EP2413946A2 (enExample)
JP (7) JP2012522511A (enExample)
KR (1) KR20120023626A (enExample)
CN (1) CN102448476A (enExample)
AU (1) AU2010236855C1 (enExample)
CA (1) CA2757457C (enExample)
IL (1) IL215463A0 (enExample)
MX (1) MX2011010197A (enExample)
RU (1) RU2011143730A (enExample)
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Cited By (5)

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JP2016513465A (ja) * 2013-03-15 2016-05-16 ミロマトリックス メディカル インコーポレイティド 膵島細胞の再細胞化のための灌流型脱細胞化肝臓の使用
JP2016524954A (ja) * 2014-05-27 2016-08-22 ノーバヘップ アーベー 生物工学で作製された同種異系弁
JP2022526727A (ja) * 2019-03-21 2022-05-26 ミロマトリックス メディカル インコーポレイテッド 摘出臓器の改善された脱細胞化
US12076461B2 (en) 2016-09-06 2024-09-03 Miromatrix Medical Inc. Use of resected liver serum for whole liver-engineering
US12263275B2 (en) 2018-06-13 2025-04-01 Miromatrix Medical Inc. Fistula filler and deployment system

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ES2384721T3 (es) 2005-08-26 2012-07-11 Regents Of The University Of Minnesota Descelularización y recelularización de órganos y tejidos
EP2588592B1 (en) * 2010-06-30 2017-09-06 Miromatrix Medical Inc. Use of perfusion decellularized organs for matched recellularization
SG188369A1 (en) 2010-09-01 2013-04-30 Univ Minnesota Methods of recellularizing a tissue or organ for improved transplantability
WO2012166668A1 (en) * 2011-05-27 2012-12-06 Christian Kazanecki Bioartificial proximal tubule systems and methods of use
CN103173920B (zh) * 2011-12-26 2014-08-27 广野精机有限公司 纬纱输送控线装置
EP2809152B1 (en) 2012-02-01 2019-11-20 Nayacure Therapeutics Ltd Method for inducing immune tolerance to organ transplants
EP2838986A4 (en) * 2012-04-18 2015-12-23 Gen Hospital Corp BIOARTIFICIAL FILTRATION ORGAN
EP2841010B1 (en) 2012-04-24 2023-08-23 Harvard Apparatus Regenerative Technology, Inc. Supports for engineered tissue scaffolds
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
US10111740B2 (en) 2012-08-21 2018-10-30 Regents Of The University Of Minnesota Decellularized biologically-engineered tubular grafts
HK1217663A1 (zh) 2013-01-09 2017-01-20 Harvard Apparatus Regenerative Technology, Inc. 合成支架
US9888680B2 (en) 2013-04-04 2018-02-13 The Trustees Of Columbia University In The City Of New York Functional recovery of human lungs for transplantation
RU2539918C1 (ru) * 2013-11-29 2015-01-27 Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации Способ получения тканеспецифического матрикса для тканевой инженерии паренхиматозного органа
CN103751843B (zh) * 2013-12-05 2015-09-16 南方医科大学珠江医院 制备全肝脏生物支架的试剂盒及全肝脏生物支架制备方法
KR101637548B1 (ko) 2013-12-24 2016-07-20 연세대학교 산학협력단 세포 배양 및 세포 분화를 위한 탈세포화 기관 매트릭스 동결건조 분쇄물 및 이의 제조 방법
CA2942714C (en) * 2014-03-14 2023-09-05 The General Hospital Corporation Lung bioreactor
CN103966092A (zh) * 2014-04-10 2014-08-06 欧东波 器官脱细胞循环灌流再生培养瓶
WO2016036764A2 (en) * 2014-09-02 2016-03-10 United Therapeutics Corporation Automated bioreactor system, system for automatically implementing protocol for decellularizing organ, and waste decontamination system
WO2016048243A1 (en) * 2014-09-23 2016-03-31 Nanyang Technological University A bioreactor module, a bioreactor system and methods for thick tissue seeding and cultivation in an hirearchical organization and physiological mimiking conditions
JP2016185115A (ja) * 2015-03-27 2016-10-27 シスメックス株式会社 臓器灌流方法および臓器灌流装置
CN106148270B (zh) * 2015-04-13 2019-09-06 中国科学院大连化学物理研究所 一种用于生物人工肝支持系统的三维微肝组织单元的构建方法
CN104771788B (zh) * 2015-05-05 2017-08-25 北京帝康医药投资管理有限公司 一种基于大网膜脱细胞基质的组织工程皮肤及其构建方法
CN106693055A (zh) * 2015-07-26 2017-05-24 复旦大学附属华山医院 一种小脑脱细胞再生生物支架及其制备方法和用途
ES2749160T3 (es) 2015-09-11 2020-03-19 Massachusetts Gen Hospital Regeneración de un lecho vascular pulmonar funcional
WO2017136786A1 (en) * 2016-02-05 2017-08-10 The Trustees Of Columbia University In The City Of New York Rigionally specific tissua-derived extracellular metrix
WO2017176919A1 (en) 2016-04-05 2017-10-12 Regents Of The University Of Minnesota Engineered tissues having structural components embedded therein, and methods of making and using
ITUA20164238A1 (it) * 2016-06-09 2017-12-09 G F S P A Metodo e apparato per la decellularizzazione di organi
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